Complete List of Signaling Pathway Reporters

QIAGEN offers a wide selection of cell-based assays for measuring cellular signaling pathways. The Cignal Reporter System measures pathway activation using rigorously engineered transcription factor reporters available in either a DNA-based or lentiviral delivery format. Furthermore, scientists can measure an individual signaling pathway or a group of related-pathways. Find your pathway.

Amino Acid Deprivation

Name	Transcription Factor	Delivery	Detection	Cat. No.
AARE Reporter	ATF4/ATF3/ATF2	DNA-based	Luciferase	CCS-8034L

Androgen

Name	Transcription Factor	Delivery	Detection	Cat. No.
AR Reporter	Androgen Receptor	DNA-based	Luciferase	CCS-1019L
AR Lenti Reporter		Lentiviral	Luciferase	CLS-8019L

Antioxidant Response

Name	Transcription Factor	Delivery	Detection	Cat. No.
ARE Reporter	Nrf2 & Nrf1	DNA-based	Luciferase	CCS-5020L
ARE Lenti Reporter		Lentiviral	Luciferase	CLS-2020L
ARE Lenti Reporter		Lentiviral	GFP	CLS-7020G

ATF6

Name	Transcription Factor	Delivery	Detection	Cat. No.
ATF6 Reporter	ATF6	DNA-based	Luciferase	CCS-9031L

Cancer (10-Pathway Array)

Name	Delivery	Reporter Gene	Format	Cat. No.
Cancer 10-pathway Reporter Kit	DNA-based	Luciferase	Tube	CCA-001L
Cancer 10-pathway Reporter Kit	DNA-based	Luciferase	Plate (3/12)	CCA-101L
Cancer 10-pathway Lenti Reporter Kit	Lentiviral	Luciferase	Tube	CLA-001L

C/EBP

Name	Transcription Factor	Delivery	Detection	Cat. No.
C/EBP Reporter	C/EBP	DNA-based	Luciferase	CCS-001L
C/EBP Lenti Reporter		Lentiviral	Luciferase	CLS-001L

cAMP/PKA

Name	Transcription Factor	Delivery	Detection	Cat. No.
CRE Reporter	CREB	DNA-based	Luciferase	CCS-002L
CRE Reporter		DNA-based	GFP	CCS-002G
CRE Lenti Reporter		Lentiviral	Luciferase	CLS-002L
CRE Lenti Reporter		Lentiviral	GFP	CLS-002G

Cell Cycle

Name	Transcription Factor	Delivery	Detection	Cat. No.
E2F/DP1 Reporter	E2F/DP1	DNA-based	Luciferase	CCS-003L
E2F/DP1 Lenti Reporter		Lentiviral	Luciferase	CLS-003L

Development (10-Pathway Array)

Name	Delivery	Reporter Gene	Format	Cat. No.
Development 10-pathway Reporter Kit	DNA-based	Luciferase	Tube	CCA-003L
Development 10-pathway Reporter Kit	DNA-based	Luciferase	Plate (3/12)	CCA-103L
Development 10-pathway Lenti Reporter Kit	Lentiviral	Luciferase	Tube	CLA-003L

DNA Damage

Name	Transcription Factor	Delivery	Detection	Cat. No.
P53 Reporter	p53	DNA-based	Luciferase	CCS-004L
P53 Lenti Reporter		Lentiviral	Luciferase	CLS-004L

EGR1

Name	Transcription Factor	Delivery	Detection	Cat. No.
EGR1 Reporter	EGR1	DNA-based	Luciferase	CCS-8021L
EGR1 Lenti Reporter		Lentiviral	Luciferase	CLS-5021L

ER Stress

Name	Transcription Factor	Delivery	Detection	Cat. No.
ERSE Reporter	CBF/NF-Y/YY1	DNA-based	Luciferase	CCS-2032L

Estrogen

Name	Transcription Factor	Delivery	Detection	Cat. No.
ER Reporter	Estrogen Receptor	DNA-based	Luciferase	CCS-005L

GATA

Name	Transcription Factor	Delivery	Detection	Cat. No.
GATA Receptor	GATA	DNA-based	Luciferase	CCS-1035L

Glucocorticoid

Name	Transcription Factor	Delivery	Detection	Cat. No.
GR Reporter	Glucocorticoid Receptor	DNA-based	Luciferase	CCS-006L

GPCR Signaling (10 pathway Array) New

Name	Delivery	Reporter Gene	Format	Cat. No.
GPCR Signaling 10-pathway Reporter Kit	DNA-based	Luciferase	Tube	CCA-009L
GPCR Signaling 10-pathway Reporter Kit	DNA-based	Luciferase	Plate (2/12)	CCA-109L

Heat Shock

Name	Transcription Factor	Delivery	Detection	Cat. No.
HSF Reporter	HSF	DNA-based	Luciferase	CCS-4023L

Heavy Metal Stress

Name	Transcription Factor	Delivery	Detection	Cat. No.
MTF1 Reporter	MTF1	DNA-based	Luciferase	CCS-5033L

Hedgehog

Name	Transcription Factor	Delivery	Detection	Cat. No.
GLI Reporter	GLI	DNA-based	Luciferase	CCS-6030L

HNF4  New

Name	Transcription Factor	Delivery	Detection	Cat. No.
HNF4 Reporter	HNF4	DNA-based	Luciferase	CCS-3039L

Hypoxia

Name	Transcription Factor	Delivery	Detection	Cat. No.
HIF Reporter	HIF1a	DNA-based	Luciferase	CCS-007L
HIF Lenti Reporter		Lentiviral	Luciferase	CLS-007L
HIF Lenti Reporter		Lentiviral	GFP	CLS-007G

Interferon Regulatory Factor  New

Name	Transcription Factor	Delivery	Detection	Cat. No.
IRF1 Reporter	IRF1	DNA-based	Luciferase	CCS-7040L

Immune Response (10-Pathway Array)

Name	Delivery	Reporter Gene	Format	Cat. No.
Immune Response 10-pathway Reporter Kit	DNA-based	Luciferase	Tube	CCA-002L
Immune Response 10-pathway Reporter Kit	DNA-based	Luciferase	Plate (3/12)	CCA-102L
Immune Response 10-pathway Lenti Reporter Kit	Lentiviral	Luciferase	Tube	CLA-002L

Interferon Type I

Name	Transcription Factor	Delivery	Detection	Cat. No.
ISRE Reporter	STAT1/ STAT2	DNA-based	Luciferase	CCS-008L
ISRE Lenti Reporter		Lentiviral	Luciferase	CLS-008L

Interferon Gamma

Name	Transcription Factor	Delivery	Detection	Cat. No.
GAS Reporter	STAT1	DNA-based	Luciferase	CCS-009L
GAS Lenti Reporter		Lentiviral	Luciferase	CLS-009L

KLF4

Name	Transcription Factor	Delivery	Detection	Cat. No.
KLF4 Reporter	KLF4	DNA-based	Luciferase	CCS-4036L

Liver X Receptor  New

Name	Transcription Factor	Delivery	Detection	Cat. No.
LXR Reporter	LXR	DNA-based	Luciferase	CCS-0041L

MAPK/ERK

Name	Transcription Factor	Delivery	Detection	Cat. No.
SRE Reporter	ELK1/SRF	DNA-based	Luciferase	CCS-010L
SRE Reporter		DNA-based	GFP	CCS-010G
SRE Lenti Reporter		Lentiviral	Luciferase	CLS-010L
SRE Lenti Reporter		Lentiviral	GFP	CLS-010G

MAPK/JNK

Name	Transcription Factor	Delivery	Detection	Cat. No.
AP1 Reporter	AP1	DNA-based	Luciferase	CCS-011L
AP1 Reporter		DNA-based	GFP	CCS-011G
AP1 Lenti Reporter		Lentiviral	Luciferase	CLS-011L
AP1 Lenti Reporter		Lentiviral	GFP	CLS-011G

MEF2

Name	Transcription Factor	Delivery	Detection	Cat. No.
MEF2 Reporter	MEF2	DNA-based	Luciferase	CCS-7024L
MEF2 Lenti Reporter		Lentiviral	Luciferase	CLS-4024L

Myc

Name	Transcription Factor	Delivery	Detection	Cat. No.
Myc Reporter	Myc/Max	DNA-based	Luciferase	CCS-012L
Myc Lenti Reporter		Lentiviral	Luciferase	CLS-012L

Nanog

Name	Transcription Factor	Delivery	Detection	Cat. No.
Nanog Reporter	Nanog	DNA-based	Luciferase	CCS-7037L

NFkB

Name	Transcription Factor	Delivery	Detection	Cat. No.
NFkB Reporter	NFKB	DNA-based	Luciferase	CCS-013L
NFkB Reporter		DNA-based	GFP	CCS-013G
NFkB Lenti Reporter		Lentiviral	Luciferase	CLS-013L
NFkB Lenti Reporter		Lentiviral	GFP	CLS-013G

Notch

Name	Transcription Factor	Delivery	Detection	Cat. No.
RBP-Jk Reporter	RBP-Jk	DNA-based	Luciferase	CCS-014L
RBP-Jk Lenti Reporter		Lentiviral	Luciferase	CLS-014L
RBP-Jk Lenti Reporter		Lentiviral	GFP	CLS-014G

Oct4

Name	Transcription Factor	Delivery	Detection	Cat. No.
Oct4 Reporter	Oct4	DNA-based	Luciferase	CCS-0025L

Pax6  New

Name	Transcription Factor	Delivery	Detection	Cat. No.
Pax6 Reporter	Pax6	DNA-based	Luciferase	CCS-3042L

PI3K/AKT

Name	Transcription Factor	Delivery	Detection	Cat. No.
FoxO Reporter	FoxO	DNA-based	Luciferase	CCS-1022L
FoxO Lenti Reporter		Lentiviral	Luciferase	CLS-8022L

PKC/Ca++

Name	Transcription Factor	Delivery	Detection	Cat. No.
NFAT Reporter	NFAT	DNA-based	Luciferase	CCS-015L
NFAT Lenti Reporter		Lentiviral	Luciferase	CLS-015L

PPAR

Name	Transcription Factor	Delivery	Detection	Cat. No.
PPAR Reporter	PPAR	DNA-based	Luciferase	CCS-3026L

Progesterone  New

Name	Transcription Factor	Delivery	Detection	Cat. No.
PR Reporter	Progesterone Receptor	DNA-based	Luciferase	CCS-6043L

Retinoic Acid

Name	Transcription Factor	Delivery	Detection	Cat. No.
RARE Reporter	Retinoic Acid Receptor	DNA-based	Luciferase	CCS-016L
RARE Lenti Reporter		Lentiviral	Luciferase	CLS-016L

Retinoid X  New

Name	Transcription Factor	Delivery	Detection	Cat. No.
RXR Reporter	RXR Reporter	DNA-based	Luciferase	CCS-9044L

RTK Signaling (10 pathway Array)  New

Name	Delivery	Reporter Gene	Format	Cat. No.
RTK Signaling 10-pathway Reporter Kit	DNA-based	Luciferase	Tube	CCA-010L
RTK Signaling 10-pathway Reporter Kit	DNA-based	Luciferase	Plate (2/12)	CCA-110L

Signal Transduction  New

Name	Transcription Factor	Delivery	Detection	Cat. No.
Signal Transduction	Signal Transduction	DNA-based	Luciferase	CCA-901L

Sox2

Name	Transcription Factor	Delivery	Detection	Cat. No.
Sox2 Reporter	Sox2	DNA-based	Luciferase	CCS-0038L

SP1

Name	Transcription Factor	Delivery	Detection	Cat. No.
SP1 Reporter	SP1	DNA-based	Luciferase	CCS-6027L
SP1 Lenti Reporter		Lentiviral	Luciferase	CLS-3027L

STAT3

Name	Transcription Factor	Delivery	Detection	Cat. No.
STAT3 Reporter	STAT3	DNA-based	Luciferase	CCS-9028L
STAT3 Lenti Reporter		Lentiviral	Luciferase	CLS-6028L

TGFb

Name	Transcription Factor	Delivery	Detection	Cat. No.
SMAD Reporter	SMAD2 SMAD3 SMAD4	DNA-based	Luciferase	CCS-017L
SMAD Reporter		DNA-based	GFP	CCS-017G
SMAD Lenti Reporter		Lentiviral	Luciferase	CLS-017L

Toxicity (10-Pathway Array)

Name	Delivery	Reporter Gene	Format	Cat. No.
Toxicity 10-pathway Reporter Kit	DNA-based	Luciferase	Tube	CCA-004L
Toxicity 10-pathway Reporter Kit	DNA-based	Luciferase	Plate (3/12)	CCA-104L
Toxicity 10-pathway Lenti Reporter Kit	Lentiviral	Luciferase	Tube	CLA-004L

Transfection Optimization (10-Pathway Array)  New

Name	Delivery	Reporter Gene	Format	Cat. No.
Transfection Optimization 10-pathway Reporter Kit	DNA-based	Luciferase	Plate (2/12)	CCA-999L

Vitamin D

Name	Transcription Factor	Delivery	Detection	Cat. No.
VDRE Reporter	VitaminD Receptor	DNA-based	Luciferase	CCS-2029L

Wnt

Name	Transcription Factor	Delivery	Detection	Cat. No.
TCF/LEF Reporter	TCF/LEF	DNA-based	Luciferase	CCS-018L
TCF/LEF Reporter		DNA-based	GFP	CCS-018G
TCF/LEF Lenti Reporter		Lentiviral	Luciferase	CLS-018L
TCF/LEF Lenti Reporter		Lentiviral	GFP	CLS-018G

Xenobiotic  New

Name	Transcription Factor	Delivery	Detection	Cat. No.
XRE Reporter	AhR	DNA-based	Luciferase	CCS-2045L