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Biomarkers

Biomarkers, as defined by NIH, are "characteristics that are objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention." A biomarker has to be reliable, measurable, specific, and predicative. Understanding the multivariate nature of a disease and drug response depends on molecular profiling at epigenetic, genetic, and protein levels. QIAGEN's PCR Arrays, microRNA Arrays, Epigenetics ChIP Arrays, Methylation PCR Arrays, and Biology-on-Arrays can all be used to identify and validate biomarkers. See details here.

Recommended Pathways For Biomarkers
Breast Cancer New
Cancer microRNA
Cancer PathwayFinder
Cell Cycle
Cell Lineage Identification
Cell Motility
Chemokines & Receptors
Common Cytokines
Cytokines & Chemokines
Embryonic Stem Cells
Epithelial to Mesenchymal Transition (EMT)
Extracellular Matrix and Adhesion Molecules
Homeobox (HOX) Genes
JAK / STAT Signaling Pathway
miFinder
miRNome
NFkB Signaling Pathway
NFkB Signaling Targets
Ovarian Cancer New
Stem Cells
Stem Cell Transcription Factors
TGFß / BMP Signaling Pathway
TGFß Signaling Targets
WNT Signaling Pathway New
WNT Signaling Targets