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EpiTect ChIP PCR Array - Epigenetic Regulation

EpiTect ChIP PCR Arrays are an innovative approach for the simultaneous analysis of DNA-protein interactions using Chromatin Immunoprecipitation (ChIP) enriched genomic DNA across a focused panel of genes. The carefully selected gene panels included in the EpiTect ChIP PCR Arrays represent an epigenetically controlled biological pathway or disease state.

Why ChIP PCR Array?

  • Biology & Disease Focused: 
    Simultaneously analyze the epigenetic & transcriptional regulation of a panel of 84 genes involved in a biological pathway or disease state using a 96 or 384-well PCR Array.
  • Small Sample Requirement: 
    As few as 1 million cells per ChIP array
  • Easy to Use: 
    Straightforward and streamlined procedure, ready to use in any laboratory with a real-time PCR instrument.

EpiTect ChIP PCR Arrays for Epigenetic Regulation:

Apoptosis

NFκB Signaling Pathway

Cancer Drug Targets

Notch Signaling Pathway

Cell Cycle

Oncogenes & Tumor Suppressor Genes

Cell Lineage Identification

Polycomb & Trithorax Complexes

Common Cytokines

Polycomb & Trithorax Target Genes

DNA Damage Signaling Pathway

Stem Cell Transcription Factors

DNA Repair

T Helper Cell Differentiation

Epithelial to Mesenchymal Transition (EMT)

TGFb Signaling Pathway

Homeobox (HOX) Genes

Toll-Like Receptor Signaling Pathway

Inflammatory Responses

WNT Signaling Pathway

 

Custom EpiTect ChIP PCR Arrays -

How it Works - Sample prep to analyzed data in a work day.

Performance Data

Applications

EpiTect ChIP PCR Arrays provide streamlined approaches to:

  1. Study biology or disease-focused gene regulation by histone modification and DNA binding;
  2. Monitor chromatin structure dynamics;
  3. Validate ChIP-on-chip or ChIP-seq results.

The EpiTect ChIP PCR Arrays are also powerful tools for studying gene regulation mechanisms behind the gene expression changes observed with RT² Profiler PCR Arrays.

To view an application example for stem cells and development, please click [here]. A list of peer-reviewed publications including the EpiTect ChIP System can be seen on our Publications page.

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