Inflammatory Response & Autoimmunity miRNA PCR Array

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Mouse Inflammatory Response & Autoimmunity miRNA PCR Array: MIMM-105Z
The Mouse Inflammatory Response & Autoimmunity miScript miRNA PCR Array profiles the expression of 84 miRNAs predicted to regulate the expression of proinflammatory or antiinflammatory genes. This array provides researchers with a convenient way to quickly analyze the miRNAs most likely to be relevant to inflammatory and autoimmune disorders. These miRNAs have been carefully selected based on those predicted by bioinformatic algorithms and databases to regulate genes known to be relevant to inflammation. The profiling results from this array can serve as a useful molecular marker for the study of normal and pathological inflammation. The results may also provide a deeper understanding of the molecular mechanisms regulating inflammatory gene expression by miRNA. A set of controls present on this array enables data analysis using the ΔΔCT method of relative quantification, assessment of reverse transcription performance, and assessment of PCR performance. Using SYBR Green-based real-time PCR, the expression of a focused panel of miRNAs predicted to regulate inflammatory and autoimmune response genes can be easily and reliably analyzed with this miScript miRNA PCR Array. miScript miRNA PCR Arrays are intended for molecular biology applications. This product is not intended for the diagnosis, prevention or treatment of a disease. 96-well, 384-well ( 4 x 96 ), and Rotor-Disc 100 formats are available. See the complete miRNA PCR Array list

Functional miRNA Grouping

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Reagents & Software

Pathway Source References Gene Table
let-7a-5p, let-7b-5p, let-7c-5p, let-7d-5p, let-7e-5p, let-7f-5p, let-7g-5p, let-7i-5p, miR-98-5p: Casp3, Ccr7, Fgf11, Fgf5, Gdf6, Il13, Masp1, Olr1, Osmr. miR-106a-5p, miR-106b-5p, miR-17-5p, miR-20a-5p, miR-20b-5p, miR-93-5p: F3, Mgll, Mink1, Osm, Pdcd1lg2, Ptger3, Stat3. miR-1192, miR-495-3p: Atrn, Bcl11a, Clcf1, Cyp26b1, Fgf7, Ptpra. miR-126-5p: Ap3b1, Cast, Cntnap2, Fgf7, Gfra2, Hdac4, Hipk2, Il13, Il17a, Il1f5, Il7, Ptger3. miR-128-3p: Bmi1, Csf1, Hipk2, Lifr, Nfx1, Pik3r1. miR-130a-3p, miR-130b-3p, miR-301a-3p, miR-301b, miR-721: Cast, Cbfb, Chst1, Eda, Erbb2ip, Hprt1, Impdh1, Inhbb, Irf1, Plaa, Pparg, Tnf. miR-135a-5p: Fgf11, Nampt, Sdcbp, Sp3, Tnfsf4, Txndc5. miR-140-5p, miR-876-3p: Bmp2, Fgf9, Hdac4, Hdac7, Rac1, Spred1, Tnfsf8, Vegfa. miR-144-3p: Cxcl12, Eda, Gdf10, Lifr, Ptgs2, Tnfsf11, Ttn. miR-155-5p: Cebpb, Cyp26b1, Fgf7, Gdf6, Ms4a1, Sdcbp, Sp3. miR-15a-5p, miR-15b-5p, miR-16-5p, miR-195a-5p, miR-322-5p, miR-497-5p: Cd28, Eda, Fgf7, Ghr, Ifnk, Il10ra, Pik3r1, Spred1, Vegfa. miR-181a-5p, miR-181b-5p, miR-181c-5p, miR-181d-5p: Cd4, Il1a, Il7, Lif, Phf20l1, Prkcd, Tnf, Tnfrsf11b, Txndc5. miR-182-5p: Bcl11a, Chst1, Fgf9, Gdf6, Hdac9, Ndrg1, Rac1, Sh2d1a, Sp3, Zfp36. miR-186-5p: Cast, Cntnap2, Cxcl13, Gdf6, Il13ra1, Pdgfc, Vegfa. miR-19a-3p, miR-19b-3p: Cast, Cbfb, Chst1, Cntfr, Cxcl12, F3, Impdh1, Plaa, Tnf. miR-200c-3p, miR-429-3p: Gpr68, Hmgb3, Il13, Ntf3, Prkca, Ripk2, Vegfa. miR-221-3p, miR-222-3p: Cbfb, Cd4, Cxcl12, Fos, Hipk2, Lifr, Ntf3, Spred2. miR-23a-3p, miR-23b-3p: Btla, Ccl7, Cxcl12, Erbb2ip, Fas, Grem1, Irf1, Prkca, Stat5b, Tnfaip6, Tpst1. miR-26a-5p, miR-26b-5p: Cmtm4, Inhbb, Pawr, Ppp3cb, Prkcd, Prkcq, Ptgs2, Srgap1. miR-27a-3p, miR-27b-3p: Bmi1, Bmp3, Cd28, Cntnap2, Csf1, Fgf1, Grem1, Hipk2, Irf4, Lifr, Mstn, Pparg, Rgs1. miR-291a-3p, miR-294-3p, miR-295-3p, miR-302b-3p, miR-302d-3p: Bcl11a, Bcl6, Cdkn1a, Cyp26b1, Dock2, F3, Il28ra, Lefty1, Lefty2. miR-466d-3p: Bmp3, Cebpb, Cmtm8, Cntnap2, Hdac4, Il12b, Il1a, Il3, Lyst, Pik3r1, Prkca, Sele, Sp3, Spred1, Spred2, Vegfa. miR-29a-3p, miR-29b-3p, miR-29c-3p: Atrn, Bcl11a, Hdac4, Il1rap, Lif, Pdgfc, Tnfrsf1a, Vegfa, Zfp36. miR-30a-5p, miR-30b-5p, miR-30c-5p, miR-30d-5p, miR-30e-5p, miR-384-5p: Cbfb, Chst1, Chst2, Hdac9, Hipk2, Ifnar2, Il1a, Irf4, Lepr, Lifr, Lyst, Pawr, Pik3cd. miR-325-3p: Akt1, Cd86, Cdkn1a, Cxcl13, Cxcr3, Ephx2, F2, Fcer1a, Grem1, Il1r1, Il22ra2, Il23a, Impdh2, Ntf3, Pik3r1. miR-338-5p: Atrn, Cast, Cyp26b1, Hdac4, Hipk2, Hmgb3, Il19, Nfkb1, Ntf3, Ptx3, Sh2d1a, Sp3. miR-340-5p: Bcl11a, Bmi1, Cast, Cmtm6, Cntnap2, Cyp26b1, Fgf7, Hdac4, Hipk2, Il10, Il4, Nfkb1, Osm. miR-350-3p: Cntnap2, Cyp26b1, Ghr, II1rap, II1m, Spred2. miR-369-3p: Ccl22, Cebpb, Gfra2, Inhbb, Prkca, Sp3, Spred1. miR-410-3p: Csf2, F3, Fgf7, Il4, Nr3c1, Pdgfa, Sp3, Vegfa. miR-466k: Atrn, Bmp3, Bmp4, Cd40lg, Chst2, Gfra2, Il28ra, Inhba, Itgam, Muc4. miR-568: Cd40, Cmtm6, Cyp26b1, Inhbb, Sp3, Suv39h2 miR-590-3p: Btla, Ccl5, Cd28, Cx3cl1, Fcgr2b, Fgf5, Hipk2, Il17f, Sp3. miR-694: Ccl8, Gdf6, Hipk2, Il1rap, Il7, Nr3c1, Prkca, Sh2d1a, Sp3. miR-712-5p: Bcl6, Cntnap2, Csf1, Il2ra, Inhba, Itgam, Lepr, Lif, Pou2f2, Stat5a, Vegfa. miR-743a-3p, miR-743b-3p: Cyp26b1, Fgf5, Hdac4, Hipk2, Il13ra1, Inhbb, Ppp3cb. miR-9-5p: Ap3b1, Cmtm6, Cxcl11, Hdac5, Inhbb, Pdgfc.
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Functional miRNA Grouping

How It Works

Manual & Resources

Reagents & Software

What miScript miRNA PCR Arrays offer?
   Guaranteed Performance* - ready-to-use for gene expression analysis
   Time & Cost Saving - less than 30 min hands-on time to analyze 84 or 372 miRNA
   Simple Data Analysis - easy-to-use Excel-Based Data Analysis Template

Layout and Controls: miScript miRNA PCR Arrays are available in 96-well, 384-well, and Rotor-Disc 100 formats. Included on each array is a set of six normalization controls as well as controls to assess RNA recovery, reverse transcription performance, and PCR performance.

You can easily perform a PCR Array experiment in your own laboratory, or send your samples to us and take advantage of our PCR Array Gene Expression Analysis Services.

*: when using the Complete miRNA PCR Array System.

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