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Online Seminars

SABiosciences is pleased to provide free, on-line educational resources covering relevant tools and techniques for gene and protein expression analysis, and cell-based gene function analysis. We offer live webinars, prerecorded and PDF formatted presentations.

See the instructions for the Web Seminars

October 2014
Monday
Tuesday
Wednesday
Thursday
Friday

1

Oxidative Stress Research Solutions

Host–pathogen interactions

2

NGS: an introduction to technology and applications

Circulating Biomarkers - PreAMP technology

3

6

Tumor heterogeneity

7

miRNA biomarker discovery

QPCR Introduction

8

Microbiome: From identification to characterization

9

NGS: targeted enrichment for translational research

Insulin resistance

10

Oxidative Stress Research Solutions

13

Tumor heterogeneity analysis

14

miRNA overview

PCR Arrays for Pathway Analysis

15

Research tools for the innate immune system

Inflammation, ROS and aging

miRNA biomarker discovery

16

NGS: targeted enrichment for clinical research

Stem cell overview

17

Tumor heterogeneity

20

Inherited disease

21

miRNAs expression and quantitation

PCR Array Data Analysis Tutorial

22

Toll-like Receptors in Inflammation

miRNA overview

23

NGS data anlaysis

Molecular Mechanisms of Neurodegeneration

24

long noncoding RNA (lncRNA)

27

long noncoding RNA (lncRNA)

28

Functional analysis of miRNAs

29

long noncoding RNA (lncRNA)

miRNAs expression and quantitation

30

long noncoding RNA (lncRNA)

31

long noncoding RNA (lncRNA)

Current Seminar Titles Available:

Focus Title
1.  PCR ArrayPCR Array Data Analysis Tutorial
2.  PCR ArrayPCR Arrays: The Real Pioneer in Real-Time PCR Analysis of Biological Pathways
3.  QPCR IntroductionIntroduction to Real Time PCR (Q-PCR/qPCR/qrt-PCR)
4.  Oxidative Stress Research SolutionsOxidative Stress: New Research Solutions
5.  miRNAsThe miRNA revolution: An introduction to microRNA biogenesis, function & analysis
6.  miRNAsmiRNA Quantitation: From experimental design through data analysis
7.  PCR Arrays in ImmunologyExploring the first line of defense: research tools for the innate immune system
8.  Copy number analysisCopy Number: Variation and Alteration Analysis Strategies
9.  Inflammation and TLRToll-like Receptors in Inflammation
10.  Neurodegeneration MechanismsMolecular Mechanisms of Neurodegeneration
11.  miRNAsFunctional analysis of miRNAs
12.  Next-generation sequencingNext-generation sequencing, an introduction to technology and applications
13.  Next-generation sequencingNext-generation sequencing data analysis for genetic profiling
14.  Stem cellStem cell: overview and key stem cell signaling pathways
15.  Microbial PCR ArraysMicrobiome: From identification to characterization
16.  miRNAsMicroRNA biomarker discovery - overcoming limiting sample material
17.  Next-generation sequencingTumor heterogeneity: mechanisms, clinical implications and analysis
18.  Host–Pathogen InteractionsHost–Pathogen Interactions: Molecular Basis and Host Defense Mechanisms
19.  PreAMP for qBiomarker somatic mutationCirculating Biomarkers: New solutions for RNA and DNA
20.  miScript miRNA for plantsPlant miRNAs: New focused genomic solutions
21.  Next-generation sequencingTargeted enrichment for next-generation sequencing: applications in translational research
22.  Next-generation sequencingTargeted enrichment for next-generation sequencing: applications in clinical research
23.  PCR ArraysHow Inflammation Drives Aging: Exploring the Mechanisms
24.  lncRNANew advances in long noncoding RNA (lncRNA) research
25.  qBiomarker ArraysA PCR-based approach for analyzing tumor heterogeneity
26.  PCR ArraysCancer & Immunity Crosstalk: Research Solutions and Strategies
27.  PCR ArraysCancer Stem Cells: Cancer Stem Cell Biology and Tumor Metastasis

PCR Array Data Analysis Tutorial

With a live demonstration using actual PCR array data, learn how easy it is to use our data analysis Web portal to calculate fold-differences in gene expression from your raw real-time PCR threshold cycles.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, November 19, 2014 at 1:00 PM Eastern    Status: Available Reserve
Tuesday, December 16, 2014 at 9:30 AM Eastern    Status: Available Reserve

PCR Arrays: The Real Pioneer in Real-Time PCR Analysis of Biological Pathways

In this 45-minute Webinar, see how the PCR array has led the way toward simple and accurate real-time PCR analysis of relevant biological pathways and diseases. Learn about the stringent performance built into the technology to ensure its sensitivity, specificity, reproducibility, and reliability. Find out how researchers like you have applied PCR arrays to their cancer, immunology, and toxicology research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, November 12, 2014 at 1:00 PM Eastern    Status: Available Reserve
Tuesday, December 9, 2014 at 9:30 AM Eastern    Status: Available Reserve

Introduction to Real Time PCR (Q-PCR/qPCR/qrt-PCR)

Real-time polymerase chain reaction (qPCR) is the most sensitive and reliable method for the detection and quantification of nucleic acids. This 45-minute webinar introduces the concepts of real-time PCR and how to conduct a real-time PCR assay. The topics that will be covered include an overview of real-time PCR chemistries, protocols, quantification methods, real-time PCR applications, and factors for success. This webinar is for both beginners that are new to real-time PCR as well as experienced users.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, November 5, 2014 at 1:00 PM Eastern    Status: Available Reserve
Tuesday, December 2, 2014 at 9:30 AM Eastern    Status: Available Reserve

Oxidative Stress: New Research Solutions

Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that arises from persistent elevation of Reactive Oxygen Species (ROS) production. Besides endogenous sources of ROS, such as those produced by mitochondria, peroxisomes, and inflammatory cell activation, there exist multiple exogenous sources of ROS, including environmental pollutants, pharmaceutical agents, and industrial toxins. When not counterbalanced by antioxidant defenses of the cell, oxidative stress damages vital cellular macromolecules, including DNA, protein, and lipids.  Oxidative stress disrupts essential cellular functions and is implicated in several human diseases, including cancer, Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.  This webinar will focus on providing a detailed introduction to oxidative stress, outline of the cellular antioxidant defense mechanisms, and current research tools that detect oxidative stress in vitro.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, November 10, 2014 at 9:30 AM Eastern    Status: Available Reserve
Friday, December 19, 2014 at 1:00 PM Eastern    Status: Available Reserve

The miRNA revolution: An introduction to microRNA biogenesis, function & analysis

miRNA plays a critical role in many biological processes such as differentiation and development, cell signaling, response to infection, and other challenges. Recent studies have shown overwhelming evidence that aberration in miRNA expression is causal or an indicator of many disease processes including cancer. Currently there is a race to find and develop miRNAs as biomarkers and therapeutics. To win the race, it is important to have a strong understanding of miRNA and the challenges of miRNA research. The webinar will cover the biology of miRNA, the key challenges associated with miRNA research, and the latest advances in miRNA research technology.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, November 11, 2014 at 1:00 PM Eastern    Status: Available Reserve
Wednesday, December 10, 2014 at 1:00 PM Eastern    Status: Available Reserve

miRNA Quantitation: From experimental design through data analysis

miRNAs play a critical role in many biological processes including neuronal cell fate, hematology, apoptosis and developmental biology. Increasing evidence has shown that aberrations in microRNA regulation are associated with many disease processes. This webinar will discuss the challenges associated with miRNA quantification by real-time PCR, and the latest strategies for miRNA quantification and profiling. The critical parameters of profiling miRNA gene expression will also be presented. Come and learn how you can apply these tools in your miRNA research!

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, November 18, 2014 at 1:00 PM Eastern    Status: Available Reserve
Wednesday, December 17, 2014 at 1:00 PM Eastern    Status: Available Reserve

Exploring the first line of defense: research tools for the innate immune system

The innate immune system executes crucial and unique functions for host defense against infection. This webinar provides an overview of the most important cellular and molecular players of innate immunity and discusses their functions in a variety of disease states. We also introduce research technologies for exploring innate immune activity in your system through profiling of gene expression and cytokines, signal transduction pathway analysis and more, all in the context.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, November 18, 2014 at 9:30 AM Eastern    Status: Available Reserve
Monday, December 8, 2014 at 1:00 PM Eastern    Status: Available Reserve

Copy Number: Variation and Alteration Analysis Strategies

Structural changes in the genome result in either increasing or decreasing the number of copies present for different genomic loci. These changes can occur in the germ line and are heritable or can occur in somatic cells de novo. Alterations in gene copy number have profound effects on human biology and are associated with both developmental disorders and diseases. This webinar will begin with a general introduction of structural genomics followed by a review of historical approaches to measure changes in copy number. The webinar will conclude with an introduction of today’s most advanced techniques for measuring copy number and strategies to improve your genomic and translational studies. Learn how to apply these genomics tools to your research!

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, November 19, 2014 at 9:30 AM Eastern    Status: Available Reserve
Tuesday, December 16, 2014 at 1:00 PM Eastern    Status: Available Reserve

Toll-like Receptors in Inflammation

"Toll-like receptors (TLRs) have been implicated in both innate and adaptive immunity-induced inflammation, thereby playing critical roles in providing the host with short- and long-term protection against infections.. This webinar will provide an overview of the roles that TLRs play in the regulation of Inflammation and solutions for studying these roles. An overview of TLR-mediated inflammation, the key signaling players involved in TLR-mediated inflammation, and the contribution of TLR-mediated inflammation to various physiological processes will be presented. Please come and learn about the state-of-the-art research tools for analyzing TLR-mediated inflammation and its regulation. "

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, November 25, 2014 at 9:30 AM Eastern    Status: Available Reserve
Friday, December 12, 2014 at 1:00 PM Eastern    Status: Available Reserve

Molecular Mechanisms of Neurodegeneration

Common molecular mechanisms and pathways leading to neurodegeneration, such as Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease or Multiple Sclerosis, will be discussed in this 45-minute webinar. Research and therapeutic strategies will be presented. Please join us to find out how these discoveries and tools can be used to facilitate your neurodegeneration research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, November 13, 2014 at 9:30 AM Eastern    Status: Available Reserve
Thursday, December 11, 2014 at 9:30 AM Eastern    Status: Available Reserve

Functional analysis of miRNAs

Understanding the function and targets of miRNA is important, but challenging research. Since one miRNA can potentially target several genes, finding and validating a specific miRNA-mRNA interaction often involves multiple molecular techniques. In this webinar we will highlight the use of miRNA mimics, inhibitors and target protectors to increase, decrease and adjust the cellular concentration of miRNA and disrupt specific miRNA-mRNA interactions. We will also present a ready-to-use screening tool for identifying miRNA targets in your samples. Lastly, we will show how miRNA expression data can be used to predict mRNA targets and how qPCR can be used to validate predicted interactions.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, November 5, 2014 at 11:00 AM Eastern    Status: Available Reserve
Tuesday, November 25, 2014 at 1:00 PM Eastern    Status: Available Reserve

Next-generation sequencing, an introduction to technology and applications

Next-generation sequencing (NGS) technology has revolutionized the study of the genomes, transcriptomes and epigenomes of any species. NGS employs massively parallel sequencing to poduce millions of sequences at once and delivering fast, inexpensive, and accurate genome information. This webinar will provide a technical overview of DNA/RNA preprocessing, template preparation, sequencing, and data analysis. It will also cover the applications for NGS technologies, including guidelines for how to select the technology that will best address your biological question of interest.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, November 3, 2014 at 1:00 PM Eastern    Status: Available Reserve
Wednesday, December 3, 2014 at 9:30 AM Eastern    Status: Available Reserve

Next-generation sequencing data analysis for genetic profiling

Next-generation employs parallel sequencing process to produce millions of raw sequencing reads. Several steps including assembly, alignment, variant calling, filtering, and annotation are involved in converting raw sequencing reads into an understanding of functional biology. In this webinar, we will discuss the challenges of NGS data analysis and solution provided by the QIAGEN NGS data analysis portal for identifying genetic variants from cell, tissue, and FFPE samples. Using raw sequencing data, we will demonstrate how our web-based data analysis portal can be used to discover known as well as novel variants and derive a biological meaningful interpretation of NGS data.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, November 24, 2014 at 1:00 PM Eastern    Status: Available Reserve
Thursday, December 18, 2014 at 9:30 AM Eastern    Status: Available Reserve

Stem cell: overview and key stem cell signaling pathways

The webinar will overview the key signaling pathways critical for embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) maintenance and differentiation, including Fibroblast Growth Factor, Hedgehog, Notch, TGFb and WNT. The major receptors and transcription factors of these signaling pathways, and stem-cell specific markers, and stem cell differentiation markers will also be presented. Qiagen has developed various techniques for profiling, screening and validating discrete biological processes during the various steps from reprogramming through terminal differentiation. Application examples will be presented. Come and learn how you can apply these tools to your research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, November 20, 2014 at 9:30 AM Eastern    Status: Available Reserve
Thursday, December 4, 2014 at 1:00 PM Eastern    Status: Available Reserve

Microbiome: From identification to characterization

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, November 11, 2014 at 9:30 AM Eastern    Status: Available Reserve
Friday, December 5, 2014 at 1:00 PM Eastern    Status: Available Reserve

MicroRNA biomarker discovery - overcoming limiting sample material

This webinar presents an integrated, PCR-based system that reduces the amount of sample required for full miRNome profiling and provides unparalleled reproducibility and precision. This advance opens up new possibilities for biomarker development.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, November 4, 2014 at 1:00 PM Eastern    Status: Available Reserve
Wednesday, December 3, 2014 at 1:00 PM Eastern    Status: Available Reserve

Tumor heterogeneity: mechanisms, clinical implications and analysis

What is tumor heterogeneity? In this webinar we will cover tumor heterogeneity and strategies to analyze it. We will go over current strategies used to analyze tumor heterogeneity and discuss some of the tools that can used in tumor heterogeneity research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, November 5, 2014 at 9:30 AM Eastern    Status: Available Reserve
Tuesday, December 2, 2014 at 1:00 PM Eastern    Status: Available Reserve

Host–Pathogen Interactions: Molecular Basis and Host Defense Mechanisms

Host–pathogen interactions are strikingly complex during infection. This webinar provides an overview of the molecular basis of these intricate interactions; the impact of microbiota on innate and adaptive immunity, metabolism, and insulin resistance; and host defense mechanisms, including newly reported inflammasome-mediated responses and miRNA-mediated responses. Various research tools will be introduced to simplify and streamline each step of studying the host response, enabling analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction pathway activation.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, November 4, 2014 at 9:30 AM Eastern    Status: Available Reserve
Monday, December 1, 2014 at 1:00 PM Eastern    Status: Available Reserve

Circulating Biomarkers: New solutions for RNA and DNA

The promise of circulating biomarkers is to enable minimally-invasive monitoring of specific molecules that yield predictive or prognostic information. However, that promise cannot be achieved until reliable screening and profiling tools become available to identify specific RNA or DNA molecules with informational value. This process is complicated by the dilution of these valuable molecules by the vast excess of nucleic acids that are not changing or not relevant as biomarkers. QIAGEN has developed solutions to help enrich, amplify and profile nucleic acids that are in circulation, such as tumor-derived DNA that carries a specific mutation or miRNAs that establish a specific expression signature. The webinar will describe solutions from sample preparation to molecule detection that will screen, profile and monitor putative biomarkers. The application examples will highlight new tools for exosomes, cfDNA, and circulating miRNA.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, December 11, 2014 at 1:00 PM Eastern    Status: Available Reserve

Plant miRNAs: New focused genomic solutions

Plant miRNAs play a necessary role in processes such as development, disease resistance and stress response. These small non-coding RNAs are thought to regulate gene expression in plants at the post-transcriptional level by targeting mRNAs for cleavage. These targeted alterations in gene expression are mediated by differential expression of hundreds of mature miRNAs that each bind to specific sequences in the target mRNAs. Therefore, profiling the coordinate regulation and expression of mature plant miRNAs provides invaluable insight into mechanisms that an organism is using to develop tissue, protect itself from drought or some disease. Until now, universal profiling of mature plant miRNAs by qRT-PCR was virtually non-existent because polyadenylation-based reverse transcription reaction occur with very low efficiency because of the biochemical nature of plant miRNAs. QIAGEN has released a unique solution that allows universal reverse transcription of all mature plant miRNAs in a tissue.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, November 6, 2014 at 1:00 PM Eastern    Status: Available Reserve
Thursday, December 4, 2014 at 9:30 AM Eastern    Status: Available Reserve

Targeted enrichment for next-generation sequencing: applications in translational research

"This webinar will discuss the most efficient and cost-effective way to carry out a successful NGS experiment. The GeneRead DNA QuantiMIZE Kits enable determining the optimum conditions for targeted enrichment of DNA isolated from biological samples. GeneRead DNAseq Targeted Panels allows you to quickly and reliably sequence your genes of interest. Applications in translational research will be presented. "

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, November 10, 2014 at 1:00 PM Eastern    Status: Available Reserve
Wednesday, December 10, 2014 at 9:30 AM Eastern    Status: Available Reserve

Targeted enrichment for next-generation sequencing: applications in clinical research

Learn how PCR-enabled targeted enrichment will allow you to detect known and discover novel variants with high accuracy, sensitivity, precision and reproducibility. The GeneRead DNAseq system is available for every gene, or a collection of genes, in the human genome, thereby providing you the ability to selectively enrich the genes that matter to you. The application examples will be focused on clinical samples and research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, November 17, 2014 at 1:00 PM Eastern    Status: Available Reserve
Wednesday, December 17, 2014 at 9:30 AM Eastern    Status: Available Reserve

How Inflammation Drives Aging: Exploring the Mechanisms

Many modern diseases, including cancer, cardiovascular disease, diabetes, liver disease, arthritis, and neurodegenerative disease, are related to aging, and intensive research is being conducted to discover both the mechanisms of aging itself as well as its relation to these conditions. This webinar provides an update on how inflammation leads to aging (defined as low regenerative potential) through DNA damage, telomere dysfunction, cellular senescence, and oxidative stress. The NFkB target COX-2 also plays a major role in this process, and recent studies suggest that aging rate may be influenced by the feedback between inflammation, senescence, and ROS. Various assay technologies to tackle the complex signaling pathways in this process will be introduced. Please join us to learn how you can apply these advanced tools to your research!

Duration: 45 minutes followed by Q&A session.

Schedule:

Friday, November 7, 2014 at 1:00 PM Eastern    Status: Available Reserve
Monday, December 1, 2014 at 9:30 AM Eastern    Status: Available Reserve

New advances in long noncoding RNA (lncRNA) research

"Recent improvements in RNA-sequencing have led to the discovery of thousands of RNAs that do not contain any open reading frames, termed “long noncoding RNA (lncRNA)”. lncRNA expression is thought to be important for the regulation of gene (mRNA) expression through several different mechanisms, some involving competition with transcription and others involving the recruitment of specific epigenetic factors to promoter regions. lncRNA may also indirectly affect gene expression by interacting with miRNA and other cellular factors. In this webinar, we will review what is known about lncRNA and use application examples in cancer research to illustrate how expression profiling is being used to identify lncRNA biomarkers from cells, tissues, blood, and exosomes. "

Duration: 45 minutes followed by Q&A session.

Schedule:

Friday, October 31, 2014 at 11:00 AM Eastern    Status: Available Reserve
Monday, November 3, 2014 at 4:00 PM Eastern    Status: Available Reserve
Thursday, November 13, 2014 at 1:00 PM Eastern    Status: Available Reserve
Monday, November 17, 2014 at 9:30 AM Eastern    Status: Available Reserve
Friday, November 21, 2014 at 11:00 AM Eastern    Status: Available Reserve
Monday, December 8, 2014 at 9:30 AM Eastern    Status: Available Reserve
Monday, December 15, 2014 at 1:00 PM Eastern    Status: Available Reserve

A PCR-based approach for analyzing tumor heterogeneity

"Tumor heterogeneity is one of the major causes of cancer drug resistance. Understanding the factors that underlie tumor heterogeneity is critical for diagnosis, prognosis, and treatment of the disease. Experimental approaches to analyze tumor heterogeneity include high-throughput and low-throughput techniques such as array CGH, NGS, microarray, and PCR. PCR-based approaches offer several distinct advantages over the others. The webinar will cover genetic variances that cause tumor heterogeneity, critical factors for a successful PCR-based approach and data analysis"

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, November 12, 2014 at 9:30 AM Eastern    Status: Available Reserve
Tuesday, December 9, 2014 at 1:00 PM Eastern    Status: Available Reserve

Cancer & Immunity Crosstalk: Research Solutions and Strategies

In this webinar, we will discuss cancer development from an immune perspective. Immunoediting, immunosuppression, inducers of anticancer immunity, and anticancer immunotherapies will be presented. Mediators and effectors of the cross-talk between cancer and the immune system that influences the course of cancer progression will be discussed. Research solutions and therapeutic strategies will also be presented. Join us to discover how these solutions can be used to facilitate your cancer research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, November 20, 2014 at 1:00 PM Eastern    Status: Available Reserve
Monday, December 15, 2014 at 9:30 AM Eastern    Status: Available Reserve

Cancer Stem Cells: Cancer Stem Cell Biology and Tumor Metastasis

"Cancer stem cells (CSC) have been implicated in the initiation and development of cancer metastasis. These cells may provide a reservoir for the generation and propagation of mutant cells providing resistance to cancer drugs. Recently, advances in technology have allowed the prospective identification and purification of CSCs from various types of cancers for further characterization. In this webinar, we will discuss cancer stem cell biology, focusing on the key CSC molecular markers and genes regulating CSC proliferation, self-renewal, and pluripotency. Important signaling pathways such as Hippo, Hedgehog, Notch, Wnt and PI3K/AKT/mTOR will be discussed. Join us to discover how these solutions can be used to facilitate your CSC characterization as well as therapeutic target identification. "

Duration: 45 minutes followed by Q&A session.

Schedule:

Friday, November 14, 2014 at 1:00 PM Eastern    Status: Available Reserve
Thursday, December 18, 2014 at 1:00 PM Eastern    Status: Available Reserve

Note: Viewers will be asked to register before viewing the previously recorded webinars.