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Online Seminars

SABiosciences is pleased to provide free, on-line educational resources covering relevant tools and techniques for gene and protein expression analysis, and cell-based gene function analysis. We offer live webinars, prerecorded and PDF formatted presentations.

See the instructions for the Web Seminars

July 2012
Monday
Tuesday
Wednesday
Thursday
Friday

2

PCR Arrays for Pathway Analysis

3

Identify key players and regulators in cancer

4

5

PCR Array Data Analysis Tutorial

6

Functional analysis of genes, biologics & small molecules

9

RNAi Screen Design & Optimzation

10

Epigenetic Technologies for Biomedical Research

11

Research tools for the innate immune system

QPCR Introduction

12

ChIP and Real-Time PCR Technology Overview

13

Oncogenomics & cancer mutation

16

Cell Death Research Solutions

17

Wnt Signaling Research Solutions

18

Gene Network Central Tutorial

Research tools for inflammation regulation

19

Anticancer Immunity

20

Copy number: variation & alteration analysis strategies

23

Metabolism and cancer

24

Wnt application- a case study

25

Profiling DNA Methylation with PCR System

PCR Array Data Analysis Tutorial

26

RNAi Gene Knockdown with shRNA

27

Oncogenomics & cancer mutation

miRNA Expression and Function

30

Signal transduction targets

31

Cancer and Inflammation

Current Seminar Titles Available:

Focus Title
1.  PCR ArrayPCR Array Data Analysis Tutorial
2.  PCR ArrayPCR Arrays: The Real Pioneer in Real-Time PCR Analysis of Biological Pathways
3.  Epigenetic ProductsNew Epigenetic Technologies for Biomedical Research: microRNA, Chromatin IP, and DNA Methylation PCR Arrays
4.  Somatic MutationCancer Mutation Analysis Made Easy – qBiomarker Somatic Mutation PCR Arrays
5.  QPCR IntroductionIntroduction to Real Time PCR (Q-PCR/qPCR/qrt-PCR)
6.  Oxidative Stress Research SolutionsOxidative Stress: New Research Solutions
7.  PCR Arrays in ImmunologyExploring the first line of defense: research tools for the innate immune system
8.  Copy number analysisCopy Number: Variation and Alteration Analysis Strategies
9.  Inflammation and TLRToll-like Receptors in Inflammation
10.  Neurodegeneration MechanismsMolecular Mechanisms of Neurodegeneration
11.  Next-generation sequencingNext-generation sequencing, an introduction to technology and applications
12.  Next-generation sequencingNext-generation sequencing for cancer research
13.  Next-generation sequencingNext-generation sequencing data analysis for genetic profiling
14.  Insulin resistanceInsulin resistance regulation and energy metabolism
15.  Stem cellStem cell: overview and key stem cell signaling pathways
16.  Microbial PCR ArraysMicrobiome: From identification to characterization
17.  Next-generation sequencingTumor heterogeneity: mechanisms, clinical implications and analysis
18.  NGS data analysisAdvancing Biological Analysis and Interpretation in Cancer Studies
19.  Host–Pathogen InteractionsHost–Pathogen Interactions: Molecular Basis and Host Defense Mechanisms
20.  PreAMP for qBiomarker somatic mutationCirculating Biomarkers: New solutions for RNA and DNA
21.  CLC Bio Genomic Workbench An automatic pipeline to find, annotate and rank rare subclonal somatic variants in a paired tumor/normal sample

PCR Array Data Analysis Tutorial

With a live demonstration using actual PCR array data, learn how easy it is to use our data analysis Web portal to calculate fold-differences in gene expression from your raw real-time PCR threshold cycles.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, August 20, 2014 at 1:00 PM Eastern    Status: Available Reserve

PCR Arrays: The Real Pioneer in Real-Time PCR Analysis of Biological Pathways

In this 45-minute Webinar, see how the PCR array has led the way toward simple and accurate real-time PCR analysis of relevant biological pathways and diseases. Learn about the stringent performance built into the technology to ensure its sensitivity, specificity, reproducibility, and reliability. Find out how researchers like you have applied PCR arrays to their cancer, immunology, and toxicology research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, August 13, 2014 at 1:00 PM Eastern    Status: Available Reserve

New Epigenetic Technologies for Biomedical Research: microRNA, Chromatin IP, and DNA Methylation PCR Arrays

Epigenetics has grabbed the attention of many researchers by providing new insights into cell differentiation and oncogenesis. These rapidly expanding studies examine how heritable factors not coded within genomic DNA sequences regulate gene expression. Such factors include DNA methylation, chromatin remodeling due to histone modification, and even, in some cases, microRNA. The experimental methods designed to discover and correlate these factors with biological phenotypes have evolved. However, many still suffer from poor sensitivity and reliability, low-throughput, and unnecessary complexity. This Webinar introduces advanced yet easy-to-use real-time PCR array technologies that analyze microRNA as well as mRNA expression profiles, CpG island DNA methylation, and chromatin immunoprecipitation fractions. Find out how easily real-time PCR-based epigenetics experiments can be performed in cancer and stem cell research to better understand the molecular epigenetic mechanisms regulating key genes of interest.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, August 21, 2014 at 1:00 PM Eastern    Status: Available Reserve

Cancer Mutation Analysis Made Easy – qBiomarker Somatic Mutation PCR Arrays

How can you quickly and accurately characterize somatic mutations associated with cancer signaling pathways? Come join the Webinar to learn about the newest real-time, PCR-based product: qBiomarker Somatic Mutation PCR Arrays. Somatic mutations occur as single or multiple mutations within a gene or a panel of genes associated with tumorigenesis, such as genes in the EGFR, ErbB2, FLT3, and PDGF pathways. Responses to treatment regimens or biological phenotypes may differ based on a cells somatic mutation profile. Each qBiomarker Somatic Mutation PCR Array contains a panel of 5' nuclease assays for a stringently selected set of pathway focused somatic mutations, gene copy number controls, and PCR quality controls. Learn how you can profile the somatic mutation status in your samples with a simple 2-step protocol with the pathway-focused qBiomarker Somatic Mutation PCR Arrays.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, August 12, 2014 at 9:30 AM Eastern    Status: Available Reserve

Introduction to Real Time PCR (Q-PCR/qPCR/qrt-PCR)

Real-time polymerase chain reaction (qPCR) is the most sensitive and reliable method for the detection and quantification of nucleic acids. This 45-minute webinar introduces the concepts of real-time PCR and how to conduct a real-time PCR assay. The topics that will be covered include an overview of real-time PCR chemistries, protocols, quantification methods, real-time PCR applications, and factors for success. This webinar is for both beginners that are new to real-time PCR as well as experienced users.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, August 6, 2014 at 1:00 PM Eastern    Status: Available Reserve

Oxidative Stress: New Research Solutions

Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that arises from persistent elevation of Reactive Oxygen Species (ROS) production. Besides endogenous sources of ROS, such as those produced by mitochondria, peroxisomes, and inflammatory cell activation, there exist multiple exogenous sources of ROS, including environmental pollutants, pharmaceutical agents, and industrial toxins. When not counterbalanced by antioxidant defenses of the cell, oxidative stress damages vital cellular macromolecules, including DNA, protein, and lipids.  Oxidative stress disrupts essential cellular functions and is implicated in several human diseases, including cancer, Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis.  This webinar will focus on providing a detailed introduction to oxidative stress, outline of the cellular antioxidant defense mechanisms, and current research tools that detect oxidative stress in vitro.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, August 14, 2014 at 1:00 PM Eastern    Status: Available Reserve

Exploring the first line of defense: research tools for the innate immune system

The innate immune system executes crucial and unique functions for host defense against infection. This webinar provides an overview of the most important cellular and molecular players of innate immunity and discusses their functions in a variety of disease states. We also introduce research technologies for exploring innate immune activity in your system through profiling of gene expression and cytokines, signal transduction pathway analysis and more, all in the context.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, August 21, 2014 at 9:30 AM Eastern    Status: Available Reserve

Copy Number: Variation and Alteration Analysis Strategies

Structural changes in the genome result in either increasing or decreasing the number of copies present for different genomic loci. These changes can occur in the germ line and are heritable or can occur in somatic cells de novo. Alterations in gene copy number have profound effects on human biology and are associated with both developmental disorders and diseases. This webinar will begin with a general introduction of structural genomics followed by a review of historical approaches to measure changes in copy number. The webinar will conclude with an introduction of today’s most advanced techniques for measuring copy number and strategies to improve your genomic and translational studies. Learn how to apply these genomics tools to your research!

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, August 19, 2014 at 9:30 AM Eastern    Status: Available Reserve

Toll-like Receptors in Inflammation

"Toll-like receptors (TLRs) have been implicated in both innate and adaptive immunity-induced inflammation, thereby playing critical roles in providing the host with short- and long-term protection against infections.. This webinar will provide an overview of the roles that TLRs play in the regulation of Inflammation and solutions for studying these roles. An overview of TLR-mediated inflammation, the key signaling players involved in TLR-mediated inflammation, and the contribution of TLR-mediated inflammation to various physiological processes will be presented. Please come and learn about the state-of-the-art research tools for analyzing TLR-mediated inflammation and its regulation. "

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, August 28, 2014 at 9:30 AM Eastern    Status: Available Reserve

Molecular Mechanisms of Neurodegeneration

Common molecular mechanisms and pathways leading to neurodegeneration, such as Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease or Multiple Sclerosis, will be discussed in this 45-minute webinar. Research and therapeutic strategies will be presented. Please join us to find out how these discoveries and tools can be used to facilitate your neurodegeneration research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, August 28, 2014 at 1:00 PM Eastern    Status: Available Reserve

Next-generation sequencing, an introduction to technology and applications

Next-generation sequencing (NGS) technology has revolutionized the study of the genomes, transcriptomes and epigenomes of any species. NGS employs massively parallel sequencing to poduce millions of sequences at once and delivering fast, inexpensive, and accurate genome information. This webinar will provide a technical overview of DNA/RNA preprocessing, template preparation, sequencing, and data analysis. It will also cover the applications for NGS technologies, including guidelines for how to select the technology that will best address your biological question of interest.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, August 4, 2014 at 1:00 PM Eastern    Status: Available Reserve

Next-generation sequencing for cancer research

DNA sequence information is important for virtually all branches of biomedical research. Given the genetic aspect of the disease, cancer research is at the forefront of genome sequencing. Next-generation sequencing (NGS) has been adapted as a technology of choice for cataloguing mutations in multiple cancer types that can be translated into new diagnostic, prognostic, and therapeutic targets. In this webinar, we will discuss the most biologically efficient and cost-effective way to use NGS technology in cancer research. A new QIAGEN GeneRead DNAseq targeted enrichment system will be introduced that will allow you to quickly and reliably sequence your genes of interest.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, August 11, 2014 at 1:00 PM Eastern    Status: Available Reserve

Next-generation sequencing data analysis for genetic profiling

Next-generation employs parallel sequencing process to produce millions of raw sequencing reads. Several steps including assembly, alignment, variant calling, filtering, and annotation are involved in converting raw sequencing reads into an understanding of functional biology. In this webinar, we will discuss the challenges of NGS data analysis and solution provided by the QIAGEN NGS data analysis portal for identifying genetic variants from cell, tissue, and FFPE samples. Using raw sequencing data, we will demonstrate how our web-based data analysis portal can be used to discover known as well as novel variants and derive a biological meaningful interpretation of NGS data.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, August 18, 2014 at 1:00 PM Eastern    Status: Available Reserve

Insulin resistance regulation and energy metabolism

Insulin resistance and glucose intolerance are a hallmark of Type II diabetes and have been closely associated with obesity. PPARgamma and mTORC2 are two key regulators of insulin sensitivity. Regulation of glucose metabolism, along with the relationship between glucose, lipid and energy metabolism will be discussed in this webinar. Research solutions and application examples will be presented. Join us to learn how these technologies can be applied to your research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, August 7, 2014 at 1:00 PM Eastern    Status: Available Reserve

Stem cell: overview and key stem cell signaling pathways

The webinar will overview the key signaling pathways critical for embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) maintenance and differentiation, including Fibroblast Growth Factor, Hedgehog, Notch, TGFb and WNT. The major receptors and transcription factors of these signaling pathways, and stem-cell specific markers, and stem cell differentiation markers will also be presented. Qiagen has developed various techniques for profiling, screening and validating discrete biological processes during the various steps from reprogramming through terminal differentiation. Application examples will be presented. Come and learn how you can apply these tools to your research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Wednesday, August 27, 2014 at 1:00 PM Eastern    Status: Available Reserve

Microbiome: From identification to characterization

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, August 14, 2014 at 9:30 AM Eastern    Status: Available Reserve

Tumor heterogeneity: mechanisms, clinical implications and analysis

What is tumor heterogeneity? In this webinar we will cover tumor heterogeneity and strategies to analyze it. We will go over current strategies used to analyze tumor heterogeneity and discuss some of the tools that can used in tumor heterogeneity research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, August 5, 2014 at 9:30 AM Eastern    Status: Available Reserve

Advancing Biological Analysis and Interpretation in Cancer Studies

Deep sequencing technologies are enabling critical insights into all aspects of cancer genomics. The combination of targeted gene panels and knowledge-driven analytics can help you quickly and cost-effectively investigate the basic mechanisms of cancers. In this 45-minute webinar, we will demonstrate how to compare and contrast cancer cell lines sequenced using the GeneRead DNAseq Human Colon Cancer Gene Panel and analyzed with Ingenuity Variant Analysis. We will show the intuitive user interface in Variant Analysis, which enables you to easily narrow down your focus to recurring somatic variants. You will see how the rich biological content from the Ingenuity Knowledge Base helps you identify drug sensitivity/resistance variants based on pharmacogenomic findings and then overlay relevant pathways and drug candidates. Please join us to learn how you can apply these innovative approaches in your own research.

Duration: 45 minutes followed by Q&A session.

Schedule:

Monday, August 25, 2014 at 1:00 PM Eastern    Status: Available Reserve

Host–Pathogen Interactions: Molecular Basis and Host Defense Mechanisms

Host–pathogen interactions are strikingly complex during infection. This webinar provides an overview of the molecular basis of these intricate interactions; the impact of microbiota on innate and adaptive immunity, metabolism, and insulin resistance; and host defense mechanisms, including newly reported inflammasome-mediated responses and miRNA-mediated responses. Various research tools will be introduced to simplify and streamline each step of studying the host response, enabling analysis of gene expression and regulation, epigenetic modification, genotyping, and signal transduction pathway activation.

Duration: 45 minutes followed by Q&A session.

Schedule:

Thursday, August 7, 2014 at 9:30 AM Eastern    Status: Available Reserve

Circulating Biomarkers: New solutions for RNA and DNA

The promise of circulating biomarkers is to enable minimally-invasive monitoring of specific molecules that yield predictive or prognostic information. However, that promise cannot be achieved until reliable screening and profiling tools become available to identify specific RNA or DNA molecules with informational value. This process is complicated by the dilution of these valuable molecules by the vast excess of nucleic acids that are not changing or not relevant as biomarkers. QIAGEN has developed solutions to help enrich, amplify and profile nucleic acids that are in circulation, such as tumor-derived DNA that carries a specific mutation or miRNAs that establish a specific expression signature. The webinar will describe solutions from sample preparation to molecule detection that will screen, profile and monitor putative biomarkers. The application examples will highlight new tools for exosomes, cfDNA, and circulating miRNA.

Duration: 45 minutes followed by Q&A session.

Schedule:

Friday, August 22, 2014 at 11:00 AM Eastern    Status: Available Reserve

An automatic pipeline to find, annotate and rank rare subclonal somatic variants in a paired tumor/normal sample

Identifying and characterizing somatic variants in deep genome sequence data from tumor samples remains challenging and time-consuming. Of special interest in cancer research and diagnostics is the detection and annotation of low frequency somatic variants, which are just in a small proportion of cells of the primary tumor. Such variants can drive tumor spread and recurrence. This webinar will give you insights in how to identify low frequency somatic variants from a tumor/normal matched sample pair using CLC Cancer Research Workbench.

Duration: 45 minutes followed by Q&A session.

Schedule:

Tuesday, August 26, 2014 at 9:30 AM Eastern    Status: Available Reserve

Note: Viewers will be asked to register before viewing the previously recorded webinars.