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Home > Resources > Publications
Publications Citing SABiosciences Products
RT² Profiler PCR Arrays
| Angiogenesis |
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Airoldi I, Di Carlo E, Cocco C, Taverniti G, D'Antuono T,
Ognio E, Watanabe M, Ribatti D, Pistoia V. Endogenous IL-12 triggers an
antiangiogenic program in melanoma cells. Proc Natl Acad Sci U S A. 2007
Mar 6;104(10):3996-4001. Epub 2007 Feb 23 |
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Basile DP, Fredrich K, Chelladurai B, Leonard EC, Parrish
AR Renal ischemia reperfusion inhibits VEGF expression and induces
ADAMTS-1, a novel VEGF inhibitor. Am J Physiol Renal Physiol. 2008
Apr;294(4):F928-36. Epub 2008 Feb 13. |
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Rangel-Moreno J, Hartson L, Navarro C, Gaxiola M, Selman
M, Randall TD. Inducible bronchus-associated lymphoid tissue (iBALT) in
patients with pulmonary complications of rheumatoid arthritis. J Clin
Invest. 2006 Dec;116(12):3183-94. |
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van Beem RT, Noort WA, Voermans C, Kleijer M, ten Brinke
A, van Ham SM, van der Schoot CE, Zwaginga JJ The presence of activated
CD4(+) T cells is essential for the formation of colony-forming
unit-Endothelial cells by CD14(+) Cells. J Immunol. 2008 Apr
1;180(7):5141-8 |
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Brant KA, Fabisiak JP Nickel and the microbial toxin, MALP-2, stimulate proangiogenic mediators from human lung fibroblasts via a HIF-1alpha and COX-2-mediated pathway. Toxicol Sci. 2009 Jan;107(1):227-37. Epub 2008 Oct 1
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| Liu Z, Kobayashi K, van Dinther M, van Heiningen SH, Valdimarsdottir G, van Laar T, Scharpfenecker M, Lowik CW, Goumans MJ, Ten Dijke P, Pardali E. VEGF and inhibitors of TGFbeta type-I receptor kinase synergistically promote J Cell Sci. 2009 Sep 15;122(Pt 18):3294-302. Epub 2009 Aug 25. | PUBMED |
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| McElroy MK, Kaushal S, Tran Cao HS, Moossa AR, Talamini MA, Hoffman RM, Bouvet M. Upregulation of thrombospondin-1 and angiogenesis in an aggressive human Mol Cancer Ther. 2009 Jul;8(7):1779-86. Epub 2009 Jul 7. | PUBMED |
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| Atmaca H, Gorumlu G,
Karaca B, Degirmenci M, Tunali D, Cirak Y, Purcu DU, Uzunoglu S, Karabulut
B, Sanli UA, Uslu R. Combined gossypol and zoledronic acid treatment results
in synergistic induction of cell death and regulates angiogenic molecules in
ovarian cancer cells. Eur Cytokine Netw. 2009 Sep;20(3):121-30. | PUBMED |
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| Wang R, Chadalavada K, Wilshire J, Kowalik
U, Hovinga KE, Geber A, Fligelman B, Leversha M, Brennan C, Tabar V.
Glioblastoma stem-like cells give rise to tumour endothelium. Nature. 2010
Dec 9;468(7325):829-33. | PUBMED |
| Apoptosis |
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Dickson EW, Hogrefe CP, Ludwig PS, Ackermann LW, Stoll LL,
Denning GM Exercise Enhances Myocardial Ischemic Tolerance via an Opioid
Receptor-Dependent Mechanism. Am J Physiol Heart Circ Physiol. 2007 Oct
19; [Epub ahead of print] |
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Lai YM, Mohammed KA, Nasreen N, Baumuratov A, Bellew BF,
Antony VB. Induction of cell cycle arrest and apoptosis by BCG infection
in cultured human bronchial airway epithelial cells. Am J Physiol Lung
Cell Mol Physiol. 2007 Aug;293(2):L393-401. Epub 2007 May 25. |
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Raeder S, Utheim TP, Utheim OA, Nicolaissen B, Roald B,
Cai Y, Haug K, Kvalheim A, Messelt EB, Drolsum L, Reed JC, Lyberg T.
Effects of organ culture and Optisol-GS storage on structural integrity,
phenotypes, and apoptosis in cultured corneal epithelium. Invest
Ophthalmol Vis Sci. 2007 Dec;48(12):5484-93 |
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Zhan Q, Signoretti S, Whitaker-Menezes D, Friedman TM,
Korngold R, Murphy GF. Cytokeratin15-positive basal epithelial cells
targeted in graft-versus-host disease express a constitutive
antiapoptotic phenotype. J Invest Dermatol. 2007 Jan;127(1):106-15. Epub
2006 Oct 12. |
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Mayoral R, Moll?B, Flores JM, Bosc?L, Casado M, Mart韓 Sanz P. Constitutive expression of cyclooxygenase 2 transgene in hepatocytes protects against liver injury. Biochem J. 2008 Aug 1. [Epub ahead of print]
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McEuen JG, Beck SG, Bale TL. Failure to mount adaptive responses to stress results in dysregulation and cell death in the midbrain raphe J Neurosci. 2008 Aug 13;28(33):8169-77
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Bose RN, Maurmann L, Mishur RJ, Yasui L, Gupta S, Grayburn WS, Hofstetter H, Milton T. Non-DNA-binding platinum anticancer agents: Cytotoxic activities of platinum-phosphato complexes towards human ovarian cancer cells. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18314-9. Epub 2008 Nov 19
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Uetani T, Nakayama H, Okayama H, Okura T, Higaki J, Inoue H, Higashiyama S. Insufficiency of proHB-EGF shedding enhances hypoxic cell death in H9c2 cardiomyoblasts via the activation of Caspase-3 and c-JUN N-terminal kinase. J Biol Chem. 2009 Feb 4. [Epub ahead of print]
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Bok K, Prikhodko VG, Green KY, Sosnovtsev SV. Apoptosis in Murine Norovirus Infected RAW264.7 Cells is Associated with Survivin Downregulation. J Virol. 2009 Feb 11. [Epub ahead of print]
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Mhyre AJ, Marcondes AM, Spaulding EY, Deeg HJ. Stroma-dependent apoptosis in clonal hematopoietic precursors correlates with expression of PYCARD. Blood. 2009 Jan 15;113(3):649-58. Epub 2008 Oct 22
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| Pru JK, Kaneko-Tarui T, Jurisicova A, Kashiwagi A, Selesniemi K, Tilly JL. Induction of proapoptotic gene expression and recruitment of p53 herald ovarian Reprod Sci. 2009 Apr;16(4):347-56. Epub 2008 Dec 15. | PUBMED |
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| Yoshida T, Zhang Y, Rosado LA, Zhang B.
Repeated treatment with subtoxic doses of TRAIL induces resistance to
apoptosis through its death receptors in MDA-MB-231 breast cancer cells.
Mol Cancer Res. 2009 Nov;7(11):1835-44. Epub 2009 Oct 20. | PUBMED |
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| Fischer KM, Cottage CT, Wu W, Din S,
Gude NA, Avitabile D, Quijada P, Collins BL, Fransioli J, Sussman MA.
Enhancement of myocardial regeneration through genetic engineering of
cardiac progenitor cells expressing Pim-1 kinase. Circulation. 2009 Nov
24;120(21):2077-87. Epub 2009 Nov 9. | PUBMED |
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| Triana-Baltzer GB, Babizki M, Chan MC,
Wong AC, Aschenbrenner LM, Campbell ER, Li QX, Chan RW, Peiris JS,
Nicholls JM, Fang F. DAS181, a sialidase fusion protein, protects human
airway epithelium against influenza virus infection: an in vitro
pharmacodynamic analysis. J Antimicrob Chemother. 2010 Feb;65(2):275-84.
Epub 2009 Nov 26. | PUBMED |
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| Belser JA, Zeng H,
Katz JM, Tumpey TM. Cell death gene expression profile: role of RIPK2 in
dengue virus-mediated apoptosis. Virus Res. 2011 Mar;156(1-2):25-34 | PUBMED |
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| Atherosclerosis |
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Manning-Tobin JJ, Moore KJ, Seimon TA, Bell SA, Sharuk M, Alvarez-Leite JI, de Winther MP, Tabas I, Freeman MW. Loss of SR-A and CD36 Activity Reduces Atherosclerotic Lesion Complexity Without Abrogating Foam Cell Formation in Hyperlipidemic Mice. Arterioscler Thromb Vasc Biol. 2008 Oct 23. [Epub ahead of print]
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| Autophgy |
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Belser JA, Zeng H, Katz JM, Tumpey TM. Cell death gene expression profile: role
of RIPK2 in dengue virus-mediated apoptosis. Virus Res. 2011 Mar;156(1-2):25-34
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PUBMED |
| Breast
Cancer & Estrogen Receptor Signaling |
| Cooper C, Guo J, Yan Y, Chooniedass-Kothari S, Hube F, Hamedani MK, Murphy LC, Myal Y, Leygue E. Increasing the relative expression of endogenous non-coding Steroid Receptor RNA Nucleic Acids Res. 2009 Jul;37(13):4518-31. Epub 2009 May 29. | PUBMED |
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| Adams BD, Cowee DM, White BA. The role of miR-206 in the epidermal growth factor (EGF) induced repression of Mol Endocrinol. 2009 Aug;23(8):1215-30. Epub 2009 May 7. | PUBMED |
| Cancer
Pathway Finder |
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Gridley DS, Slater JM, Luo-Owen X, Rizvi A, Chapes SK, Stodieck LS, Ferguson VL, Pecaut MJ. Spaceflight effects on T lymphocyte distribution, function and gene expression. J Appl Physiol. 2009 Jan;106(1):194-202. Epub 2008 Nov 6.
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| Das KK, Bajpai M, Kong Y, Liu J, Geng X, Das KM. Mesalamine suppresses the expression of TC22, a novel tropomyosin isoform Mol Pharmacol. 2009 Jul;76(1):183-91. Epub 2009 Apr 15. | PUBMED |
| Cell
Cycle |
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Chen N, Ye XC, Chu K, Navone NM, Sage EH, Yu-Lee LY,
Logothetis CJ, Lin SH. A secreted isoform of ErbB3 promotes osteonectin
expression in bone and enhances the invasiveness of prostate cancer
cells. Cancer Res. 2007 Jul 15;67(14):6544-8 |
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Chen S, Sims GP, Chen XX, Gu YY, Chen S, Lipsky PE.
Modulatory effects of 1,25-dihydroxyvitamin D3 on human B cell
differentiation. J Immunol. 2007 Aug 1;179(3):1634-47. |
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Lu SY, Sontag DP, Detillieux KA, Cattini PA. FGF-16 is
released from neonatal cardiac myocytes and alters growth-related
signaling: a possible role in postnatal development. Am J Physiol Cell
Physiol. 2008 May;294(5):C1242-9. Epub 2008 Mar 12 |
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| Higgins S, Wong SH, Richner M, Rowe CL, Newgreen DF, Werther GA, Russo VC. Fibroblast growth factor 2 reactivates G1 checkpoint in SK-N-MC cells via Endocrinology. 2009 Sep;150(9):4044-55. Epub 2009 May 28. | PUBMED |
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| Seifert AW, Zheng Z, Ormerod BK, Cohn
MJ. Sonic hedgehog controls growth of external genitalia by regulating
cell cycle kinetics. Nat Commun. 2010 Jun 1;1:23 | PUBMED |
| Chemokines
& Receptors |
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Klopp AH, Spaeth EL, Dembinski JL, Woodward WA, Munshi A,
Meyn RE, Cox JD, Andreeff M, Marini FC Tumor irradiation increases the
recruitment of circulating mesenchymal stem cells into the tumor
microenvironment. Cancer Res. 2007 Dec 15;67(24):11687-95. |
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Miselis NR, Wu ZJ, Van Rooijen N, Kane AB Targeting
tumor-associated macrophages in an orthotopic murine model of diffuse
malignant mesothelioma. Mol Cancer Ther. 2008 Apr;7(4):788-99. Epub 2008
Mar 28 |
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Sinha S, Subramanian S, Proctor TM, Kaler LJ, Grafe M,
Dahan R, Huan J, Vandenbark AA, Burrows GG, Offner H. A promising
therapeutic approach for multiple sclerosis: recombinant T-cell receptor
ligands modulate experimental autoimmune encephalomyelitis by reducing
interleukin-17 production and inhibiting migration of encephalitogenic
cells into the CNS J Neurosci. 2007 Nov 14;27(46):12531-9. |
PUBMED |
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Sze SK, de Kleijn DP, Lai RC, Khia Way Tan E, Zhao H, Yeo
KS, Low TY, Lian Q, Lee CN, Mitchell W, El Oakley RM, Lim SK.
Elucidating the secretion proteome of human embryonic stem cell-derived
mesenchymal stem cells. Mol Cell Proteomics. 2007 Oct;6(10):1680-9. Epub
2007 Jun 11. |
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Lee PY, Kumagai Y, Li Y, Takeuchi O, Yoshida H, Weinstein J, Kellner ES, Nacionales D, Barker T, Kelly-Scumpia K, van Rooijen N, Kumar H, Kawai T, Satoh M, Akira S, Reeves WH. TLR7-dependent and FcgammaR-independent production of type I interferon in experimental mouse lupus. J Exp Med. 2008 Dec 22;205(13):2995-3006. Epub 2008 Dec 1
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Lim J, Derrick SC, Kolibab K, Yang AL, Porcelli S, Jacobs WR, Morris SL. Early pulmonary cytokine and chemokine responses in mice immunized with three different vaccines against Mycobacterium tuberculosis determined by PCR array. Clin Vaccine Immunol. 2009 Jan;16(1):122-6. Epub 2008 Nov 26.
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Fukami N, Ramachandran S, Saini D, Walter M, Chapman W, Patterson GA, Mohanakumar T. Antibodies to MHC class I induce autoimmunity: role in the pathogenesis of chronic rejection. J Immunol. 2009 Jan 1;182(1):309-18.
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| Cheung KP, Yang E, Goldrath AW. Memory-like CD8+ T cells generated during homeostatic proliferation defer to J Immunol. 2009 Sep 1;183(5):3364-72. Epub 2009 Aug 12. | PUBMED |
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| Sundararaj KP, Samuvel DJ, Li Y, Sanders JJ, Lopes-Virella MF, Huang Y. Interleukin-6 released from fibroblasts is essential for up-regulation of matrix J Biol Chem. 2009 May 15;284(20):13714-24. Epub 2009 Mar 23. | PUBMED |
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| Weiss JM, Back TC,
Scarzello AJ, Subleski JJ, Hall VL, Stauffer JK, Chen X, Micic D, Alderson
K, Murphy WJ, Wiltrout RH. Successful immunotherapy with IL-2/anti-CD40
induces the chemokine-mediated mitigation of an immunosuppressive tumor
microenvironment. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19455-60.
Epub 2009 Nov 5. | PUBMED |
| Common
Cytokines |
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Gude N, Muraski J, Rubio M, Kajstura J, Schaefer E,
Anversa P, Sussman MA. Akt promotes increased cardiomyocyte cycling and
expansion of the cardiac progenitor cell population. Circ Res. 2006 Aug
18;99(4):381-8. Epub 2006 Jul 13. |
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Keskin DB, Allan DS, Rybalov B, Andzelm MM, Stern JN,
Kopcow HD, Koopman LA, Strominger JL. TGFbeta promotes conversion of
CD16+ peripheral blood NK cells into CD16- NK cells with similarities to
decidual NK cells. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3378-83.
Epub 2007 Feb 20. |
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Sze SK, de Kleijn DP, Lai RC, Khia Way Tan E, Zhao H, Yeo
KS, Low TY, Lian Q, Lee CN, Mitchell W, El Oakley RM, Lim SK.
Elucidating the secretion proteome of human embryonic stem cell-derived
mesenchymal stem cells. Mol Cell Proteomics. 2007 Oct;6(10):1680-9. Epub
2007 Jun 11. |
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Silver RF, Walrath J, Lee H, Jacobson BA, Horton H, Bowman MR, Nocka K, Sypek JP. Human Alveolar Macrophage Gene Responses to Mycobacterium tuberculosis Strains H37Ra and H37Rv. Am J Respir Cell Mol Biol. 2008 Sep 11. [Epub ahead of print]
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| Campeau PM, Rafei M, Boivin MN, Sun Y, Grabowski GA, Galipeau J. Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals Blood. 2009 Oct 8;114(15):3181-90. Epub 2009 Jul 8. | PUBMED |
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| Myskiw C, Arsenio J, van Bruggen R, Deschambault Y, Cao J. Vaccinia virus E3 suppresses expression of diverse cytokines through inhibition J Virol. 2009 Jul;83(13):6757-68. Epub 2009 Apr 15. | PUBMED |
| Custom |
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Sonic hedgehog controls growth of external genitalia by regulating cell cycle kinetics. Nat Commun. 2010 Jun 1;1:23. 2006 Aug 17; [Epub
ahead of print] |
PUBMED |
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Bowers RR, Kim JW, Otto TC, Lane MD. Stable stem cell
commitment to the adipocyte lineage by inhibition of DNA methylation:
Role of the BMP-4 gene. Proc Natl Acad Sci U S A. 2006 Aug 17; [Epub
ahead of print] |
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Bowers RR, Kim JW, Otto TC, Lane MD. Stable stem cell
commitment to the adipocyte lineage by inhibition of DNA methylation:
Role of the BMP-4 gene. Proc Natl Acad Sci U S A. 2006 Aug 17; [Epub
ahead of print] |
PUBMED |
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Torcia MG, Santarlasci V, Cosmi L, Clemente A, Maggi L,
Mangano VD, Verra F, Bancone G, Nebie I, Sirima BS, Liotta F, Frosali F,
Angeli R, Severini C, Sannella AR, Bonini P, Lucibello M, Maggi E,
Garaci E, Coluzzi M, Cozzolino F, Annunziato F, Romagnani S, Modiano D.
Functional deficit of T regulatory cells in Fulani, an ethnic group with
low susceptibility to Plasmodium falciparum malaria. Proc Natl Acad Sci
U S A. 2008 Jan 15;105(2):646-51. Epub 2008 Jan 3 |
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Shivapurkar N, Stastny V, Okumura N, Girard L, Xie Y, Prinsen C, Thunnissen FB, Wistuba II, Czerniak B, Frenkel E, Roth JA, Liloglou T, Xinarianos G, Field JK, Minna JD, Gazdar AF. Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene. Cancer Res. 2008 Sep 15;68(18):7448-56.
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Bousquet L, Pruvost A, Guyot AC, Farinotti R, Mabondzo A. Combination of Tenofovir and Emtricitabine plus Efavirenz: In Vitro Modulation of ABC transporter and Intracellular Drug Accumulation. Antimicrob Agents Chemother. 2008 Dec 15. [Epub ahead of print]
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Bousquet L, Pruvost A, Guyot AC, Farinotti R, Mabondzo A. Combination of Tenofovir and Emtricitabine plus Efavirenz: In Vitro Modulation of ABC transporter and Intracellular Drug Accumulation. Antimicrob Agents Chemother. 2008 Dec 15. [Epub ahead of print]
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Huang J, Chen K, Huang J, Gong W, Dunlop NM, Howard OM, Bian X, Gao Y, Wang JM. Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation. Carcinogenesis. 2009 Feb;30(2):348-55. Epub 2008 Nov 26
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Chahrour M, Jung SY, Shaw C, Zhou X, Wong ST, Qin J, Zoghbi HY. MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription Science. 2008 May 30;320(5880):1224-9.
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Yamamoto H, Shigematsu H, Nomura M, Lockwood WW, Sato M, Okumura N, Soh J, Suzuki M, Wistuba II, Fong KM, Lee H, Toyooka S, Date H, Lam WL, Minna JD, Gazdar AF. PIK3CA mutations and copy number gains in human lung cancers. Cancer Res. 2008 Sep 1;68(17):6913-21.
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Birrell MA, De Alba J, Catley MC, Hardaker E, Wong S, Collins M, Clarke DL, Farrow SN, Willson TM, Collins JL, Belvisi MG. Liver X receptor agonists increase airway reactivity in a model of asthma via increasing airway smooth muscle growth. J Immunol. 2008 Sep 15;181(6):4265-71.
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| Peduto L, Dulauroy S, Lochner M, Spath GF, Morales MA, Cumano A, Eberl G. Inflammation recapitulates the ontogeny of lymphoid stromal cells. J Immunol. 2009 May 1;182(9):5789-99. | PUBMED |
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| Ianzini F, Kosmacek EA, Nelson ES, Napoli E, Erenpreisa J, Kalejs M, Mackey MA. Activation of meiosis-specific genes is associated with depolyploidization of Cancer Res. 2009 Mar 15;69(6):2296-304. Epub 2009 Mar 3. | PUBMED |
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| Schreiber TH, Deyev VV, Rosenblatt JD, Podack ER. Tumor-induced suppression of CTL expansion and subjugation by gp96-Ig Cancer Res. 2009 Mar 1;69(5):2026-33. Epub 2009 Feb 17. | PUBMED |
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| Peduto L, Dulauroy S, Lochner M, Spath GF, Morales MA, Cumano A, Eberl G. Inflammation recapitulates the ontogeny of lymphoid stromal cells. J Immunol. 2009 May 1;182(9):5789-99. | PUBMED |
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| DiMeo TA, Anderson K, Phadke P, Fan C, Perou CM, Naber S, Kuperwasser C. A novel lung metastasis signature links Wnt signaling with cancer cell Cancer Res. 2009 Jul 1;69(13):5364-73. Epub 2009 Jun 23. | PUBMED |
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| Chang BY, Zhao F, He X, Ren H, Braselmann S, Taylor V, Wicks J, Payan DG, Grossbard EB, Pine PR, Bullard DC. JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 J Immunol. 2009 Aug 1;183(3):2183-92. Epub 2009 Jul 13. | PUBMED |
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| Titterington JS, Sukhanov S, Higashi
Y, Vaughn C, Bowers C, Delafontaine P. Growth hormone-releasing
peptide-2 suppresses vascular oxidative stress in ApoE-/- mice but
does not reduce atherosclerosis. Endocrinology. 2009
Dec;150(12):5478-87. Epub 2009 Oct 9. | PUBMED |
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| Yu J, Fernández-Hernando C, Suarez Y,
Schleicher M, Hao Z, Wright PL, DiLorenzo A, Kyriakides TR, Sessa WC
Reticulon 4B (Nogo-B) is necessary for macrophage infiltration and
tissue repair Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17511-6.
Epub 2009 Sep 25. | PUBMED |
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| Chan SK, Riley PR, Price KL, McElduff
F, Winyard PJ, Welham SJ, Woolf AS, Long DA. Corticosteroid-induced
kidney dysmorphogenesis is associated with deregulated expression of
known cystogenic molecules, as well as Indian hedgehog. Am J Physiol
Renal Physiol. 2010 Feb;298(2):F346-56. Epub 2009 Dec 9. | PUBMED |
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| Bergamaschi A, David A, Le Rouzic E,
Nisole S, Barré-Sinoussi F, Pancino G. The CDK inhibitor p21Cip1/WAF1
is induced by FcgammaR activation and restricts the replication of
human immunodeficiency virus type 1 and related primate lentiviruses
in human macrophages. J Virol. 2009 Dec;83(23):12253-65. Epub 2009 Sep
16. | PUBMED |
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| DNA
Damage |
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Hoffman AE, Zheng T, Ba Y, Zhu Y. The circadian gene NPAS2, a putative tumor suppressor, is involved in DNA damage response. Mol Cancer Res. 2008 Sep;6(9):1461-8
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Chesnokova V, Wong C, Zonis S, Gruszka A, Wawrowsky K, Ren SG, Benshlomo A, Yu R. Diminished pancreatic {beta} cell mass in securin-null mice is caused by {beta} cell apoptosis and senescence. Endocrinology. 2009 Feb 12. [Epub ahead of print]
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| Santisteban M, Reiman JM, Asiedu MK, Behrens MD, Nassar A, Kalli KR, Haluska P, Ingle JN, Hartmann LC, Manjili MH, Radisky DC, Ferrone S, Knutson KL. Immune-induced epithelial to mesenchymal transition in vivo generates breast Cancer Res. 2009 Apr 1;69(7):2887-95. Epub 2009 Mar 10. | PUBMED |
| Drug
Metabolism: Phase I Enzymes |
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Ning B, Dial S, Sun Y, Wang J, Yang J, Guo L Systematic
and simultaneous gene profiling of 84 drug-metabolizing genes in primary
human hepatocytes J Biomol Screen. 2008 Mar;13(3):194-201. Epub 2008 Feb
12 |
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| ECM |
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Tian J, Pecaut MJ, Slater JM, Gridley DS.
Spaceflight modulates expression of extracellular matrix, adhesion, and
profibrotic molecules in mouse lung. J Appl Physiol. 2010
Jan;108(1):162-71. Epub 2009 Oct 22. |
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| Embryonic
stem cells |
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Meyn MA 3rd, Smithgall TE. Chemical genetics
identifies c-Src as an activator of primitive ectoderm formation in
murine embryonic stem cells. Sci Signal. 2009 Oct 13;2(92):ra64. |
PUBMED |
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| Extracellular
Matrix & Adhesion Molecules |
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Collins M, Hurford R, Chao Y, Patrick C, Langford TD.
Variability in Virus and in Host During HIV-1 Infection. Horn of Africa
Journal of AIDS. 2006 Volume III, Issue I:38-46. |
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Gelain F, Bottai D, Vescovi A, Zhang S. Designer
self-assembling Peptide nanofiber scaffolds for adult mouse neural stem
cell 3-dimensional cultures. PLoS ONE. 2006 Dec 27;1:e119. |
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Johansen LD, Naumanen T, Knudsen A, Westerlund N, Gromova
I, Junttila M, Nielsen C, Bottzauw T, Tolkovsky A, Westermarck J,
Coffey ET, Jaattela M, Kallunki T. IKAP localizes to membrane
ruffles with filamin A and regulates actin cytoskeleton organization and
cell migration. J Cell Sci. 2008 Mar 15;121(Pt 6):854-64. Epub 2008 Feb
26. |
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Nacu N, Luzina IG, Highsmith K, Lockatell V, Pochetuhen
K, Cooper ZA, Gillmeister MP, Todd NW, Atamas SP Macrophages produce TGF-beta-induced
(beta-ig-h3) following ingestion of apoptotic cells and regulate MMP14
levels and collagen turnover in fibroblasts J Immunol. 2008 Apr
1;180(7):5036-44 |
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Oumouna-Benachour K, Hans CP, Suzuki Y, Naura A, Datta R,
Belmadani S, Fallon K, Woods C, Boulares AH. Poly(ADP-ribose) polymerase
inhibition reduces atherosclerotic plaque size and promotes factors of
plaque stability in apolipoprotein E-deficient mice: effects on
macrophage recruitment, nuclear factor-kappaB nuclear translocation, and
foam cell death. Circulation. 2007 May 8;115(18):2442-50. Epub 2007 Apr
16. PUBMED |
PUBMED |
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Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T,
Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K,
Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H. Kruppel-like
factor 5 causes cartilage degradation through transactivation of matrix
metalloproteinase 9. J Biol Chem. 2008 Jul 10. [Epub ahead of
print] |
PUBMED |
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Tapia A, Salamonsen LA, Manuelpillai U, Dimitriadis E.
Leukemia inhibitory factor promotes human first trimester extravillous
trophoblast adhesion to extracellular matrix and secretion of tissue
inhibitor of metalloproteinases-1 and -2. Hum Reprod. 2008
Aug;23(8):1724-32. Epub 2008 May 20. |
PUBMED |
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Yen JH, Khayrullina T, Ganea D. PGE2-induced
metalloproteinase-9 is essential for dendritic cell migration Blood.
2007 Oct 9; [Epub ahead of print] PUBMED |
PUBMED |
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Zauli G, Corallini F, Bossi F, Fischetti F, Durigutto P,
Celeghini C, Tedesco F, Secchiero P. Osteoprotegerin increases leukocyte
adhesion to endothelial cells both in vitro and in vivo. Blood. 2007 Jul
15;110(2):536-43. Epub 2007 Mar 15. |
PUBMED |
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Zauli G, Corallini F, Bossi F, Fischetti F, Durigutto P,
Celeghini C, Tedesco F, Secchiero P. Osteoprotegerin increases leukocyte
adhesion to endothelial cells both in vitro and in vivo. Blood. 2007 Jul
15;110(2):536-43. Epub 2007 Mar 15. |
PUBMED |
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| Lucio-Eterovic AK, Piao Y, de Groot JF. Mediators of glioblastoma resistance and invasion during antivascular endothelial Clin Cancer Res. 2009 Jul 15;15(14):4589-99. Epub 2009 Jun 30. | PUBMED |
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| Kuhn AR, Schlauch K, Lao R, Halayko AJ, Gerthoffer WT, Singer CA. MicroRNA Expression in Human Airway Smooth Muscle Cells: Role of miR-25 in Am J Respir Cell Mol Biol. 2009 Jun 18. | PUBMED |
| Endothelial
Cell Biology |
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Li Z, Suzuki Y, Huang M, Cao F, Xie X, Connolly AJ, Yang
PC, Wu JC Comparison of Reporter Gene and Iron Particle Labeling for
Tracking Fate of Human Embryonic Stem Cells and Differentiated
Endothelial Cells in Living Subjects. Stem Cells. 2008 Apr;26(4):864-73.
Epub 2008 Jan 24 |
PUBMED |
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Asada S, Takahashi T, Isodono K, Adachi A, Imoto H, Ogata T, Ueyama T, Matsubara H, Oh H. Downregulation of Dicer expression by serum withdrawal sensitizes human endothelial cells to apoptosis. Am J Physiol Heart Circ Physiol. 2008 Dec;295(6):H2512-21. Epub 2008 Oct 31
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PUBMED |
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Liu Z, Kobayashi K, van Dinther M, van Heiningen SH, Valdimarsdottir G, van Laar
T, Scharpfenecker M, Löwik CW, Goumans MJ, Ten Dijke P, Pardali E VEGF and
inhibitors of TGFbeta type-I receptor kinase synergistically promote
blood-vessel formation by inducing alpha5-integrin expression. J Cell Sci. 2009
Sep 15;122(Pt 18):3294-302. Epub 2009 Aug 25
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PUBMED |
| Growth
Factors |
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Stirling DP, Liu S, Kubes P, Yong VW Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome. J Neurosci. 2009 Jan 21;29(3):753-64.
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PUBMED |
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Dunn GA, Bale TL. Maternal high-fat diet promotes body length increases and
insulin insensitivity in second-generation mice. Endocrinology. 2009
Nov;150(11):4999-5009. Epub 2009 Oct 9
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PUBMED |
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| Hypoxia
Signaling |
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Wendler CC, Amatya S, McClaskey C, Ghatpande S, Fredholm
BB, Rivkees SA. A1 adenosine receptors play an essential role in
protecting the embryo against hypoxia. Proc Natl Acad Sci U S A. 2007
Jun 5;104(23):9697-702. Epub 2007 May 23 |
PUBMED |
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Mueller BR, Bale TL. Sex-specific programming of offspring emotionality after stress early in pregnancy. J Neurosci. 2008 Sep 3;28(36):9055-65.
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PUBMED |
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| Inflammatory
Cytokines & Receptors |
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Aubin E, Lemieux R, Bazin R. Absence of cytokine
modulation following therapeutic infusion of intravenous immunoglobulin
or anti-red blood cell antibodies in a mouse model of immune
thrombocytopenic purpura. Br J Haematol. 2007 Mar;136(6):837-43. |
PUBMED |
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Dickson EW, Hogrefe CP, Ludwig PS, Ackermann LW, Stoll LL,
Denning GM Exercise Enhances Myocardial Ischemic Tolerance via an Opioid
Receptor-Dependent Mechanism. Am J Physiol Heart Circ Physiol. 2007 Oct
19; [Epub ahead of print] |
PUBMED |
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Lakshmanan U, Porter AG Caspase-4 interacts with TNF
receptor-associated factor 6 and mediates lipopolysaccharide-induced NF-kappaB-dependent
production of IL-8 and CC chemokine ligand 4 (macrophage-inflammatory
protein-1 ). J Immunol. 2007 Dec 15;179(12):8480-90 |
PUBMED |
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Rangel-Moreno J, Hartson L, Navarro C, Gaxiola M, Selman
M, Randall TD. Inducible bronchus-associated lymphoid tissue (iBALT) in
patients with pulmonary complications of rheumatoid arthritis. J Clin
Invest. 2006 Dec;116(12):3183-94. |
PUBMED |
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Sze SK, de Kleijn DP, Lai RC, Khia Way Tan E, Zhao H, Yeo
KS, Low TY, Lian Q, Lee CN, Mitchell W, El Oakley RM, Lim SK.
Elucidating the secretion proteome of human embryonic stem cell-derived
mesenchymal stem cells. Mol Cell Proteomics. 2007 Oct;6(10):1680-9. Epub
2007 Jun 11. |
PUBMED |
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Lee JK, McCoy MK, Harms AS, Ruhn KA, Gold SJ, Tansey MG. Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response. J Neurosci. 2008 Aug 20;28(34):8517-28.
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PUBMED |
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| Chittur S, Parr B, Marcovici G. Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Evid Based Complement Alternat Med. 2009 Aug 19. | PUBMED |
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| Kawaguchi A, Orba Y, Kimura T, Iha H, Ogata M, Tsuji T, Ainai A, Sata T, Okamoto T, Hall WW, Sawa H, Hasegawa H. Inhibition of the SDF-1alpha-CXCR4 axis by the CXCR4 antagonist AMD3100 Blood. 2009 Oct 1;114(14):2961-8. Epub 2009 Aug 5. | PUBMED |
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| Kanda T, Steele R, Ray R, Ray RB. Inhibition of intrahepatic gamma interferon production by hepatitis C virus J Virol. 2009 Sep;83(17):8463-9. Epub 2009 Jun 24. | PUBMED |
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| Huston JM, Rosas-Ballina M, Xue X, Dowling O, Ochani K, Ochani M, Yeboah MM, Chatterjee PK, Tracey KJ, Metz CN. Cholinergic neural signals to the spleen down-regulate leukocyte trafficking via J Immunol. 2009 Jul 1;183(1):552-9. | PUBMED |
| | |
| MacNamara KC, Racine R, Chatterjee M, Borjesson D, Winslow GM. Diminished hematopoietic activity associated with alterations in innate and Infect Immun. 2009 Sep;77(9):4061-9. Epub 2009 May 18. | PUBMED |
| | |
| Sundararaj KP, Samuvel DJ, Li Y, Sanders JJ, Lopes-Virella MF, Huang Y. Interleukin-6 released from fibroblasts is essential for up-regulation of matrix J Biol Chem. 2009 May 15;284(20):13714-24. Epub 2009 Mar 23. | PUBMED |
| | |
| Montgomery CP, Daum RS. Transcription of inflammatory genes in the lung after infection with Infect Immun. 2009 May;77(5):2159-67. Epub 2009 Feb 23. | PUBMED |
| | |
| Choi K, Ahn YH, Gibbons DL, Tran HT, Creighton CJ, Girard L, Minna JD, Qin FX, Kurie JM. Distinct biological roles for the notch ligands Jagged-1 and Jagged-2. J Biol Chem. 2009 Jun 26;284(26):17766-74. Epub 2009 Apr 27. | PUBMED |
| | |
| Rank RG, Lacy HM, Goodwin A, Sikes J,
Whittimore J, Wyrick PB, Nagarajan UM. Host chemokine and cytokine response
in the endocervix within the first developmental cycle of Chlamydia
muridarum. Infect Immun. 2010 Jan;78(1):536-44. Epub 2009 Oct 19. | PUBMED |
| | |
| Fox JG, Feng Y, Theve EJ, Raczynski AR,
Fiala JL, Doernte AL, Williams M, McFaline JL, Essigmann JM, Schauer DB,
Tannenbaum SR, Dedon PC, Weinman SA, Lemon SM, Fry RC, Rogers AB. Gut
microbes define liver cancer risk in mice exposed to chemical and viral
transgenic hepatocarcinogens. Gut. 2010 Jan;59(1):88-97. | PUBMED |
| Inflammatory
Response and Autoimmunity |
| Rafei M, Campeau PM, Wu JH, Birman E, Forner K, Boivin MN, Galipeau J. Selective inhibition of CCR2 expressing lymphomyeloid cells in experimental J Immunol. 2009 Mar 1;182(5):2620-7. | PUBMED |
| | |
| Rayner KJ, Suárez Y, Dávalos A, Parathath
S, Fitzgerald ML, Tamehiro N, Fisher EA, Moore KJ, Fernández-Hernando C.
Infection with highly pathogenic H7 influenza viruses results in an
attenuated proinflammatory cytokine and chemokine response early after
infection. J Infect Dis. 2011 Jan 1;203(1):40-8. | PUBMED |
| | |
| Zeng H, Pappas C, Katz JM, Tumpey TM. The
2009 pandemic H1N1 and triple-reassortant swine H1N1 influenza viruses
replicate efficiently but elicit an attenuated inflammatory response in
polarized human bronchial epithelial cells J Virol. 2011 Jan;85(2):686-96 | PUBMED |
| Insulin Signaling |
|
Narvaez CJ, Matthews D, Broun E, Chan M, Welsh J. Lean phenotype and resistance to diet-induced obesity in vitamin D receptor knockout mice correlates with induction of uncoupling protein-1 in white adipose tissue. Endocrinology. 2009 Feb;150(2):651-61. Epub 2008 Oct 9
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PUBMED |
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| Interferon α, β Response |
|
Tilton JC, Manion MM, Luskin MR, Johnson AJ, Patamawenu
AA, Hallahan CW, Cogliano-Shutta NA, Mican JM, Davey RT Jr, Kottilil S,
Lifson JD, Metcalf JA, Lempicki RA, Connors M. Human immunodeficiency
virus viremia induces plasmacytoid dendritic cell activation in vivo and
diminished alpha interferon production in vitro. J Virol. 2008
Apr;82(8):3997-4006. Epub 2008 Feb 6 |
PUBMED |
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Li Q, Xu B, Michie SA, Rubins KH, Schreriber RD, McDevitt HO. Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12439-44. Epub 2008 Aug 20.
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PUBMED |
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Christensen JE, Simonsen S, Fenger C, S鴕ensen MR, Moos T, Christensen JP, Finsen B, Thomsen AR. Fulminant lymphocytic choriomeningitis virus-induced inflammation of the CNS involves a cytokine-chemokine-cytokine-chemokine cascade. J Immunol. 2009 Jan 15;182(2):1079-87.
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PUBMED |
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| Interferon
(IFN) and Receptor |
| Yoshimi R, Chang TH, Wang H, Atsumi T, Morse HC 3rd, Ozato K. Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in J Immunol. 2009 Jun 15;182(12):7527-38. | PUBMED |
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DeWitte-Orr SJ, Mehta DR, Collins SE, Suthar MS, Gale M Jr, Mossman KL. Long
double-stranded RNA induces an antiviral response independent of IFN regulatory
factor 3, IFN-beta promoter stimulator 1, and IFN. J Immunol. 2009 Nov
15;183(10):6545-53. Epub 2009 Oct 28.
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PUBMED |
| JAK
/ STAT Signaling |
|
Albanesi C, Fairchild HR, Madonna S, Scarponi C, De Pit?O,
Leung DY, Howell MD. IL-4 and IL-13 negatively regulate TNF-alpha- and
IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of
cytokine signaling (SOCS)-1, and SOCS-3. J Immunol. 2007 Jul
15;179(2):984-92. |
PUBMED |
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Duechting A, Tschope C, Kaiser H, Lamkemeyer T,
Tanaka N, Aberle S, Lang F, Torresi J, Kandolf R, Bock CT. Human
Parvovirus B19 NS1 Protein Modulates Inflammatory Signaling by
Activation of STAT3/PIAS3 in Human Endothelial Cells. J Virol. 2008 Jun
11. [Epub ahead of print] |
PUBMED |
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Sze SK, de Kleijn DP, Lai RC, Khia Way Tan E, Zhao H, Yeo
KS, Low TY, Lian Q, Lee CN, Mitchell W, El Oakley RM, Lim SK.
Elucidating the secretion proteome of human embryonic stem cell-derived
mesenchymal stem cells. Mol Cell Proteomics. 2007 Oct;6(10):1680-9. Epub
2007 Jun 11. |
PUBMED |
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| Noronha AM, Liang Y, Hetzel JT, Hasturk H, Kantarci A, Stucchi A, Zhang Y, Nikolajczyk BS, Farraye FA, Ganley-Leal LM. Hyperactivated B cells in human inflammatory bowel disease. J Leukoc Biol. 2009 Oct;86(4):1007-16. Epub 2009 Jul 9. | PUBMED |
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| Torroella-Kouri M, Silvera R, Rodriguez D, Caso R, Shatry A, Opiela S, Ilkovitch D, Schwendener RA, Iragavarapu-Charyulu V, Cardentey Y, Strbo N, Lopez DM. Identification of a subpopulation of macrophages in mammary tumor-bearing mice Cancer Res. 2009 Jun 1;69(11):4800-9. Epub 2009 May 19. | PUBMED |
| Lipoprotein
Signaling & Cholesterol |
| Zhou C, King N, Chen KY, Breslow JL. Activation of pregnane X receptor induces hypercholesterolemia in wild-type and J Lipid Res. 2009 May 12. | PUBMED | | | |
| MAP
Kinase Signaling |
|
Ruettger A, Schueler S, Mollenhauer JA, Wiederanders B.
Cathepsins B, K and L are regulated by a defined collagen type II
peptide via activation of classical protein kinase C and p38 MAP kinase
in articular chondrocytes. J Biol Chem. 2007 Nov 8; [Epub ahead of
print] |
PUBMED |
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Singh S, Yin X, Pisano MM, Greene RM. Molecular profiles
of mitogen activated protein kinase signaling pathways in orofacial
development. Birth Defects Res A Clin Mol Teratol. 2007 Jan;79(1):35-44.
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PUBMED |
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| Makarenkova HP, Hoffman MP, Beenken A, Eliseenkova AV, Meech R, Tsau C, Patel VN, Lang RA, Mohammadi M. Differential interactions of FGFs with heparan sulfate control gradient formation Sci Signal. 2009 Sep 15;2(88):ra55. | PUBMED |
| NFκB Signaling |
|
Chen N, Ye XC, Chu K, Navone NM, Sage EH,
Yu-Lee LY, Logothetis CJ, Lin SH. A secreted isoform of ErbB3 promotes
osteonectin expression in bone and enhances the invasiveness of prostate
cancer cells. Cancer Res. 2007 Jul 15;67(14):6544-8. |
PUBMED |
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Chen S, Sims GP, Chen XX, Gu YY, Chen S,
Lipsky PE. Modulatory effects of 1,25-dihydroxyvitamin D3 on human B
cell differentiation. J Immunol. 2007 Aug 1;179(3):1634-47. |
PUBMED |
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Sze SK, de Kleijn DP, Lai RC, Khia Way Tan E,
Zhao H, Yeo KS, Low TY, Lian Q, Lee CN, Mitchell W, El Oakley RM, Lim
SK. Elucidating the secretion proteome of human embryonic stem
cell-derived mesenchymal stem cells. Mol Cell Proteomics. 2007
Oct;6(10):1680-9. Epub 2007 Jun 11. |
PUBMED |
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Han YM, Romero R, Kim JS, Tarca AL, Kim SK, Draghici S, Kusanovic JP, Gotsch F, Mittal P, Hassan S, Kim CJ. Region-Specific Gene Expression Profiling: Novel Evidence for Biological Heterogeneity of the Human Amnion Biol Reprod. 2008 Aug 6. [Epub ahead of print]
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PUBMED |
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Singh K, Sinha S, Malonia SK, Bist P, Tergaonkar V, Chattopadhyay S. Tumor suppressor SMAR1 represses IkappaBalpha expression and inhibits p65 transactivation through matrix attachment regions. J Biol Chem. 2009 Jan 9;284(2):1267-78. Epub 2008 Nov 3.
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PUBMED |
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| Farhana L, Dawson MI, Xu L, Fontana JA. SHP and Sin3A expression are essential for adamantyl-substituted retinoid-related Mol Cancer Ther. 2009 Jun;8(6):1625-35. Epub 2009 Jun 9. | PUBMED |
| Oxidative Stress and Antioxidant Defense |
| Chua PJ, Yip GW, Bay BH. Cell cycle arrest induced by hydrogen peroxide is associated with modulation of Exp Biol Med (Maywood). 2009 Sep;234(9):1086-94. Epub 2009 Jul 13. | PUBMED |
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| Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M. C/EBP{alpha} is required for pulmonary cytoprotection during hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2009 Aug;297(2):L286-98. Epub 2009 May 22. | PUBMED |
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| Baqai FP, Gridley DS, Slater JM, Luo-Owen X, Stodieck LS, Ferguson V, Chapes SK, Pecaut MJ. Effects of spaceflight on innate immune function and antioxidant gene expression. J Appl Physiol. 2009 Jun;106(6):1935-42. Epub 2009 Apr 2. | PUBMED |
| Chen A, Cuevas I, Kenny PA, Miyake H, Mace K, Ghajar C, Boudreau A, Bissell M, Boudreau N. Endothelial cell migration and vascular endothelial growth factor expression are Cancer Res. 2009 Aug 15;69(16):6721-9. Epub 2009 Aug 4. | PUBMED |
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Polytarchou C, Pfau R, Hatziapostolou M, Tsichlis PN The JmjC domain histone demethylase Ndy1 regulates redox homeostasis and protects cells from oxidative stress. Mol Cell Biol. 2008 Dec;28(24):7451-64. Epub 2008 Oct 6
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PUBMED |
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| Osteogenesis |
|
Gouttenoire J, Valcourt U, Bougault C, Aubert-Foucher E,
Arnaud E, Giraud L, Mallein-Gerin F. Knockdown of the intraflagellar
transport protein IFT46 stimulates selective gene expression in mouse
chondrocytes and affects early development in zebrafish. J Biol Chem.
2007 Oct 19;282(42):30960-73. Epub 2007 Aug 24 |
PUBMED |
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Wescott DC, Pinkerton MN, Gaffey BJ, Beggs KT, Milne TJ,
Meikle MC. Osteogenic gene expression by human periodontal ligament
cells under cyclic tension. J Dent Res. 2007 Dec;86(12):1212-6 |
PUBMED |
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Flowers S, Nagl NG Jr, Beck GR Jr, Moran E Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation. J Biol Chem. 2009 Jan 14. [Epub ahead of print]
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PUBMED |
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Meikle MC Northcroft Memorial Lecture 2007. A century of progress: advances in orthodontics since the foundation of the British Society for the Study of Orthodontics. J Orthod. 2008 Sep;35(3):176-90
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Xue Y, Xing Z, Hellem S, Arvidson K, Mustafa K. Endothelial cells influence the
osteogenic potential of bone marrow stromal cells. Biomed Eng Online. 2009 Nov
17;8:34.
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PUBMED |
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Zheng Z, Cohn MJ. Developmental basis of sexually dimorphic digit ratios. Proc
Natl Acad Sci U S A. 2011 Sep 27;108(39):16289-94
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PUBMED |
| p53
Signaling |
|
Brockschmidt C, Hirner H, Huber N, Eismann T, Hillenbrand
A, Giamas G, Radunsky B, Ammerpohl O, Bohm B, Henne-Bruns D, Kalthoff H,
Leithauser F, Trauzold A, Knippschild U Anti-apoptotic and
growth-stimulatory functions of CK1 delta and epsilon in ductal
adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in
vivo. Gut. 2008 Jun;57(6):799-806. Epub 2008 Jan 18. |
PUBMED |
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| Cutts BA, Sjogren AK, Andersson KM, Wahlstrom AM, Karlsson C, Swolin B, Bergo MO. Nf1 deficiency co-operates with oncogenic K-RAS to induce acute myeloid leukemia Blood. 2009 Aug 26. | PUBMED |
| | |
| Barkic M, Crnomarkovic S, Grabusic K, Bogetic I, Panic L, Tamarut S, Cokaric M, Jeric I, Vidak S, Volarevic S. The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice Mol Cell Biol. 2009 May;29(10):2489-504. Epub 2009 Mar 9. | PUBMED |
| Signal
Transduction PathwayFinder |
| Hager-Theodorides AL, Furmanski AL, Ross SE, Outram SV, Rowbotham NJ, Crompton T. The Gli3 transcription factor expressed in the thymus stroma controls thymocyte J Immunol. 2009 Sep 1;183(5):3023-32. Epub 2009 Aug 10. | PUBMED |
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| Bojanic DD, Tarr PT, Gale GD, Smith DJ, Bok D, Chen B, Nusinowitz S, Lovgren-Sandblom A, Bjorkhem I, Edwards PA. Differential expression and function of ABCG1 and ABCG4 during development and J Lipid Res. 2009 Jul 26. | PUBMED |
| | |
| Rowbotham NJ, Hager-Theodorides AL, Furmanski AL, Ross SE, Outram SV, Dessens JT, Crompton T. Sonic hedgehog negatively regulates pre-TCR-induced differentiation by a Blood. 2009 May 21;113(21):5144-56. Epub 2009 Mar 9. | PUBMED |
| | |
| Hager-Theodorides AL, Furmanski AL, Ross SE,
Outram SV, Rowbotham NJ, Crompton T The Gli3 transcription factor expressed
in the thymus stroma controls thymocyte negative selection via
Hedgehog-dependent and -independent mechanisms. J Immunol. 2009 Sep
1;183(5):3023-32. Epub 2009 Aug 10. | PUBMED |
| Stem
Cell |
| Xu XL, Xing BC, Han HB, Zhao W, Hu MH, Xu ZL,
Li JY, Xie Y, Gu J, Wang Y, Zhang ZQ. The properties of tumor-initiating
cells from a hepatocellular carcinoma patient's primary and recurrent tumor.
Carcinogenesis. 2010 Feb;31(2):167-74. Epub 2009 Nov 6. | PUBMED |
| | |
| Stress
& Toxicity PathwayFinder |
| Johnston N, Wells CW, Samuels TL, Blumin JH.
Pepsin in nonacidic refluxate can damage hypopharyngeal epithelial cells.
Ann Otol Rhinol Laryngol. 2009 Sep;118(9):677-85 | PUBMED |
| | |
| T
Cell Anergy & Immune Tolerance |
| Gorczynski RM, Chen Z, He W, Khatri I, Sun Y, Yu K, Boudakov I. Expression of a CD200 transgene is necessary for induction but not maintenance of J Immunol. 2009 Aug 1;183(3):1560-8. Epub 2009 Jul 10. | PUBMED |
| | |
| TGFβ BMP Signaling |
| Garamszegi N, Garamszegi SP, Shehadeh LA, Scully SP. Extracellular matrix-induced gene expression in human breast cancer cells. Mol Cancer Res. 2009 Mar;7(3):319-29. Epub 2009 Mar 10. | PUBMED |
| | |
| Th1,
Th2, Th3 |
|
Torcia MG, Santarlasci V, Cosmi L, Clemente A, Maggi L,
Mangano VD, Verra F, Bancone G, Nebie I, Sirima BS, Liotta F, Frosali F,
Angeli R, Severini C, Sannella AR, Bonini P, Lucibello M, Maggi E,
Garaci E, Coluzzi M, Cozzolino F, Annunziato F, Romagnani S, Modiano D.
Functional deficit of T regulatory cells in Fulani, an ethnic group with
low susceptibility to Plasmodium falciparum malaria. Proc Natl Acad Sci
U S A. 2008 Jan 15;105(2):646-51. Epub 2008 Jan 3 |
PUBMED |
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Jacob N, Yang H, Pricop L, Liu Y, Gao X, Zheng SG, Wang J, Gao HX, Putterman C, Koss MN, Stohl W, Jacob CO. Accelerated pathological and clinical nephritis in systemic lupus erythematosus-prone New Zealand Mixed 2328 mice doubly deficient in TNF receptor 1 and TNF receptor 2 via a Th17-associated pathway. J Immunol. 2009 Feb 15;182(4):2532-41
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PUBMED |
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| Roman J, Rangasamy T, Guo J, Sugunan S, Meednu N, Packirisamy G, Shimoda L, Golding A, Semenza G, Georas SN. T Cell Activation Under Hypoxic Conditions Enhances Interferon-gamma Secretion. Am J Respir Cell Mol Biol. 2009 Apr 16. | PUBMED |
| TH17
for Autoimmunity & Inflammation |
|
Lochner M, Peduto L, Cherrier M, Sawa S, Langa F, Varona
R, Riethmacher D, Si-Tahar M, Di Santo JP, Eberl G. In vivo equilibrium
of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T
cells. J Exp Med. 2008 Jun 9;205(6):1381-93. Epub 2008 May 26 |
PUBMED |
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Jacob N, Yang H, Pricop L, Liu Y, Gao X, Zheng SG, Wang J, Gao HX, Putterman C, Koss MN, Stohl W, Jacob CO. Accelerated pathological and clinical nephritis in systemic lupus erythematosus-prone New Zealand Mixed 2328 mice doubly deficient in TNF receptor 1 and TNF receptor 2 via a Th17-associated pathway. J Immunol. 2009 Feb 15;182(4):2532-41
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PUBMED |
| Toll-Like
Receptor Signaling |
|
Brant KA, Fabisiak JP. Nickel Alterations of
TLR2-Dependent Chemokine Profiles in Lung Fibroblasts are Mediated by
COX-2. Am J Respir Cell Mol Biol. 2007 Dec 20 [Epub ahead of
print] |
PUBMED |
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Ornatowska M, Azim AC, Wang X, Christman JW, Xiao L, Joo
M, Sadikot RT. Functional genomics of silencing TREM-1 on TLR4 signaling
in macrophages. Am J Physiol Lung Cell Mol Physiol. 2007
Dec;293(6):L1377-84. Epub 2007 Sep 28 |
PUBMED |
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Tilton JC, Manion MM, Luskin MR, Johnson AJ, Patamawenu
AA, Hallahan CW, Cogliano-Shutta NA, Mican JM, Davey RT Jr, Kottilil S,
Lifson JD, Metcalf JA, Lempicki RA, Connors M. Human immunodeficiency
virus viremia induces plasmacytoid dendritic cell activation in vivo and
diminished alpha interferon production in vitro. J Virol. 2008
Apr;82(8):3997-4006. Epub 2008 Feb 6 |
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Tomchuck SL, Zwezdaryk KJ, Coffelt SB,
Waterman RS, Danka ES, Scandurro AB Toll-Like Receptors on Human
Mesenchymal Stem Cells Drive their Migration and Immunomodulating
Responses. Stem Cells. 2007 Oct 4; [Epub ahead of print] |
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West J, Damania B Upregulation of the TLR3 pathway by
Kaposi's sarcoma-associated herpesvirus during primary infection. J
Virol. 2008 Jun;82(11):5440-9. Epub 2008 Mar 26 |
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Pr阬e CM, Woodward EA, Bisley J, Keith-Magee A, Nicholson SE, Hart PH. SOCS1 regulates the IFN but not NFkappaB pathway in TLR-stimulated human monocytes and macrophages. J Immunol. 2008 Dec 1;181(11):8018-26.
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PUBMED |
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Shin H, Zhang Y, Jagannathan M, Hasturk H, Kantarci A, Liu H, Van Dyke TE, Ganley-Leal LM, Nikolajczyk BS. B cells from periodontal disease patients express surface Toll-like receptor 4 J Leukoc Biol. 2008 Dec 31. [Epub ahead of print]
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Samuvel DJ, Sundararaj KP, Nareika A, Lopes-Virella MF, Huang Y. Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation. J Immunol. 2009 Feb 15;182(4):2476-84
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| Chen GY, Shiah HC, Su HJ, Chen CY, Chuang YJ, Lo WH, Huang JL, Chuang CK, Hwang SM, Hu YC. Baculovirus transduction of mesenchymal stem cells triggers the toll-like J Virol. 2009 Oct;83(20):10548-56. Epub 2009 Aug 5. | PUBMED |
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| Zhang X, Alnaeeli M, Singh B, Teng YT. Involvement of SOCS3 in regulation of CD11c+ dendritic cell-derived Infect Immun. 2009 May;77(5):2000-9. Epub 2009 Mar 2. | PUBMED |
| | |
| Soulika AM, Lee E, McCauley E, Miers L,
Bannerman P, Pleasure D Initiation and progression of axonopathy in
experimental autoimmune encephalomyelitis. J Neurosci. 2009 Nov
25;29(47):14965-79. | PUBMED |
| Transcription
Factors |
| Yuvaraj S, Griffin AC, Sundaram K, Kirkwood KL, Norris JS, Reddy SV. A novel function of CXCL13 to stimulate RANK ligand expression in oral squamous Mol Cancer Res. 2009 Aug;7(8):1399-407. Epub 2009 Aug 11. | PUBMED |
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| Middeldorp J, Kamphuis W, Sluijs JA, Achoui D, Leenaars CH, Feenstra MG, van Tijn P, Fischer DF, Berkers C, Ovaa H, Quinlan RA, Hol EM. Intermediate filament transcription in astrocytes is repressed by proteasome FASEB J. 2009 Aug;23(8):2710-26. Epub 2009 Mar 30. | PUBMED |
| Toxicology |
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Joseph, P. et al. Heme-oxygenase 1 Gene Expression is a
Marker for Hexavalent Chromium-Induced Stress and Toxicity in Human
Dermal Fibroblasts. Toxicol. Sci., Jun 2008; 103: 325 - 334. |
PUBMED |
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Marshall, N.B, et al. Functional Characterization and
Gene Expression Analysis of CD4+CD25+ Regulatory T Cells Generated in
Mice Treated with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin. J. Immunol., Aug
2008; 181: 2382 - 2391. |
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Ning, B. et al. Systematic and Simultaneous Gene
Profiling of 84 Drug-Metabolizing Genes in Primary Human Hepatocytes. J
Biomol Screen, Mar 2008; 13: 194 - 201. |
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| Tumor Metastasis |
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Wang J, Shiozawa Y, Wang J, Wang Y, Jung Y, Pienta KJ,
Mehra R, Lober R, Taichman RS The role of CXCR7/RDC1 as a chemokine
receptor for CXCL12/ SDF-1 in prostate cancer. J Biol Chem. 2007 Dec 5 [Epub
ahead of print] |
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| WNT
Signaling |
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Aslanidi G, Kroutov V, Philipsberg G, Lamb K,
Campbell-Thompson M, Walter GA, Kurenov S, Ignacio Aguirre J, Keller P,
Hankenson K, Macdougald OA, Zolotukhin S. Ectopic expression of Wnt10b
decreases adiposity and improves glucose homeostasis in obese rats. Am J
Physiol Endocrinol Metab. 2007 Sep;293(3):E726-36. Epub 2007 Jun 19 |
PUBMED |
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Giuliani N, Morandi F, Tagliaferri S,
Lazzaretti M, Donofrio G, Bonomini S, Sala R, Mangoni M, Rizzoli V.
Production of wnt inhibitors by myeloma cells: potential effects on
canonical wnt pathway in the bone microenvironment. Cancer Res. 2007 Aug
15;67(16):7665-74. |
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Guo W, Flanagan J, Jasuja R, Kirkland J, Jiang L, Bhasin
S. The Effects of Myostatin on Adipogenic Differentiation of Human Bone
Marrow-derived Mesenchymal Stem Cells Are Mediated through
Cross-communication between Smad3 and Wnt/{beta}-Catenin Signaling
Pathways. J Biol Chem. 2008 Apr 4;283(14):9136-45. Epub 2008 Jan 18. |
PUBMED |
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Hidestrand M, Richards-Malcolm S, Gurley CM, Nolen G,
Grimes B, Waterstrat A, Zant GV, Peterson CA. Sca-1-expressing
nonmyogenic cells contribute to fibrosis in aged skeletal muscle. J
Gerontol A Biol Sci Med Sci. 2008 Jun;63(6):566-79. |
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Welters HJ, Oknianska A, Erdmann KS, Ryffel GU, Morgan NG
The protein tyrosine phosphatase-BL, modulates pancreatic beta-cell
proliferation by interaction with the Wnt signaling pathway. J
Endocrinol. 2008 Jun;197(3):543-52. Epub 2008 Apr 15 |
PUBMED |
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Malhotra S, Baba Y, Garrett KP, Staal FJ, Gerstein R, Kincade PW. Contrasting responses of lymphoid progenitors to canonical and noncanonical Wnt signals. J Immunol. 2008 Sep 15;181(6):3955-64.
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Gelebart P, Anand M, Armanious H, Peters AC, Dien Bard J, Amin HM, Lai R. Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma. Blood. 2008 Dec 15;112(13):5171-9. Epub 2008 Sep 11.
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Jonassen JA, San Agustin J, Follit JA, Pazour GJ. Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease. J Cell Biol. 2008 Nov 3;183(3):377-84.
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Wu QL, Zierold C, Ranheim EA Dysregulation of frizzled 6 is a critical component of B cell leukemogenesis in a mouse model of chronic lymphocytic leukemia. Blood. 2009 Jan 28. [Epub ahead of print]
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| Ghosh MC, Collins GD, Vandanmagsar B, Patel K, Brill M, Carter A, Lustig A, Becker KG, Wood WW 3rd, Emeche CD, French AD, O'Connell MP, Xu M, Weeraratna AT, Taub DD. Activation of Wnt5A signaling is required for CXC chemokine ligand 12-mediated Blood. 2009 Aug 13;114(7):1366-73. Epub 2009 Jun 11. | PUBMED |
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| Hussain M, Rao M, Humphries AE, Hong JA, Liu F, Yang M, Caragacianu D, Schrump DS. Tobacco smoke induces polycomb-mediated repression of Dickkopf-1 in lung cancer Cancer Res. 2009 Apr 15;69(8):3570-8. Epub 2009 Apr 7. | PUBMED |
| | |
| Naik S,
Dothager RS, Marasa J, Lewis CL, Piwnica-Worms D. Vascular Endothelial
Growth Factor Receptor-1 Is Synthetic Lethal to Aberrant {beta}-Catenin
Activation in Colon Cancer. Clin Cancer Res. 2009 Dec
15;15(24):7529-7537. | PUBMED |
BACK TO TOP
SureSilencing siRNA
| Control siRNA sequence |
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| Li X, Barkho BZ, Luo Y, Smrt RD, Santistevan NJ, Liu C, Kuwabara T, Gage FH, Zhao X. Epigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural J Biol Chem. 2008 Oct 10;283(41):27644-52. Epub 2008 Aug 8. | PUBMED |
BACK TO TOP
SureSilencing shRNA Plasmids
| Cancer |
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Baritaki S, Huerta-Yepez S, Sakai T, Spandidos DA,
Bonavida B. Chemotherapeutic drugs sensitize cancer cells to
TRAIL-mediated apoptosis: up-regulation of DR5 and inhibition of Yin
Yang 1. Mol Cancer Ther. 2007 Apr;6(4):1387-99. |
PUBMED |
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Demorrow S, Francis H, Gaudio E, Ueno Y, Venter J, Onori
P, Franchitto A, Vaculin B, Vaculin S, Alpini G Anandamide inhibits
cholangiocyte hyperplastic proliferation via activation of thioredoxin
1/redox factor 1 and AP-1 activation. Am J Physiol Gastrointest Liver
Physiol. 2007 Dec 20 [Epub ahead of print] |
PUBMED |
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Demorrow S, Glaser S, Francis H, Venter J, Vaculin B,
Vaculin S, Alpini G. Opposing actions of endocannabinoids on
cholangiocarcinoma growth: Recruitment of fas and fas ligand to lipid
rafts. J Biol Chem. 2007 Apr 27;282(17):13098-113. Epub 2007 Feb 28. |
PUBMED |
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Dhakshinamoorthy S, Sridharan SR, Li L, Ng PY, Boxer LM,
Porter AG Protein/DNA arrays identify nitric oxide-regulated cis-element
and trans-factor activities some of which govern neuroblastoma cell
viability. Nucleic Acids Res. 2007;35(16):5439-51. Epub 2007 Aug 15. |
PUBMED |
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Dimple C, Nair SS, Rajhans R, Pitcheswara PR, Liu J,
Balasenthil S, Le XF, Burow ME, Auersperg N, Tekmal RR, Broaddus RR,
Vadlamudi RK. Role of PELP1/MNAR signaling in ovarian tumorigenesis.
Cancer Res. 2008 Jun 15;68(12):4902-9. |
PUBMED |
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Guo Y, Xie J, Rubin E, Tang YX, Lin F, Zi X, Hoang BH.
Frzb, a secreted Wnt antagonist, decreases growth and invasiveness of
fibrosarcoma cells associated with inhibition of Met signaling. Cancer
Res. 2008 May 1;68(9):3350-60 |
PUBMED |
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Horak CE, Lee JH, Elkahloun AG, Boissan M, Dumont S, Maga
TK, Arnaud-Dabernat S, Palmieri D, Stetler-Stevenson WG, Lacombe ML,
Meltzer PS, Steeg PS. Nm23-H1 suppresses tumor cell motility by
down-regulating the lysophosphatidic acid receptor EDG2. Cancer Res.
2007 Aug 1;67(15):7238-46. |
PUBMED |
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McFate T, Mohyeldin A, Lu H, Thakar J, Henriques J, Halim
ND, Wu H, Schell MJ, Tsang TM, Teahan O, Zhou S, Califano JA, Jeoung NH,
Harris RA, Verma A. Pyruvate dehydrogenase complex activity controls
metabolic and malignant phenotype in cancer cells. J Biol Chem. 2008 Jun
9. [Epub ahead of print] |
PUBMED |
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McGowan PM, Ryan BM, Hill AD, McDermott E, O'Higgins N,
Duffy MJ. ADAM-17 expression in breast cancer correlates with variables
of tumor progression. Clin Cancer Res. 2007 Apr 15;13(8):2335-43 |
PUBMED |
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Rajhans R, Nair HB, Nair SS, Cortez V, Ikuko K, Kirma NB,
Zhou D, Holden AE, Brann DW, Chen S, Tekmal RR, Vadlamudi RK. Modulation
of in situ Estrogen Synthesis by PELP1: Potential ER Autocrine Signaling
Loop in Breast Cancer Cells Mol Endocrinol. 2007 Dec 13 [Epub ahead of
print] |
PUBMED |
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Tirado OM, Mateo-Lozano S, Villar J, Dettin LE, Llort A,
Gallego S, Ban J, Kovar H, Notario V. Caveolin-1 (CAV1) is a target of
EWS/FLI-1 and a key determinant of the oncogenic phenotype and
tumorigenicity of Ewing's sarcoma cells. Cancer Res. 2006 Oct
15;66(20):9937-47. |
PUBMED |
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Zhao S, Venkatasubbarao K, Lazor JW, Sperry J, Jin C, Cao
L, Freeman JW Inhibition of STAT3 Tyr705 phosphorylation by Smad4
suppresses transforming growth factor beta-mediated invasion and
metastasis in pancreatic cancer cells. Cancer Res. 2008 Jun
1;68(11):4221-8 |
PUBMED |
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Saifudeen Z, Dipp S, Stefkova J, Yao X, Lookabaugh S, El-Dahr
SS. p53 regulates metanephric development. J Am Soc Nephrol. 2009
Nov;20(11):2328-37. Epub 2009 Sep 3. |
PUBMED |
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Ju CH, Chockalingam A, Leifer CA. Early response of
mucosal epithelial cells during Toxoplasma gondii infection. J Immunol.
2009 Dec 1;183(11):7420-7. Epub 2009 Nov 16. |
PUBMED |
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Richter K, Brar S, Ray M, Pisitkun P, Bolland S, Verkoczy
L, Diaz M. Speckled-like pattern in the germinal center (SLIP-GC), a
nuclear GTPase expressed in activation-induced deaminase-expressing
lymphomas and germinal center B cells. J Biol Chem. 2009 Oct
30;284(44):30652-61. Epub 2009 Sep 4. |
PUBMED |
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Li FQ, Mofunanya A, Fischer V, Hall J, Takemaru K.
Nuclear-cytoplasmic shuttling of Chibby controls beta-catenin signaling.
Mol Biol Cell. 2010 Jan;21(2):311-22. Epub 2009 Nov 25. |
PUBMED |
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Ciccone NA, Xu S, Lacza CT, Carroll RS, Kaiser UB.
Frequency-dependent regulation of follicle-stimulating hormone beta by
pulsatile gonadotropin-releasing hormone is mediated by functional
antagonism of bZIP transcription factors. Mol Cell Biol. 2010
Feb;30(4):1028-40. Epub 2009 Dec 14. |
PUBMED |
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Ungvari Z, Labinskyy N, Mukhopadhyay P, Pinto JT, Bagi Z,
Ballabh P, Zhang C, Pacher P, Csiszar A. Resveratrol attenuates
mitochondrial oxidative stress in coronary arterial endothelial cells.
Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1876-81. Epub 2009 Sep
11. |
PUBMED |
| Cardiovascular Disease |
|
Torella D, Curcio A, Gasparri C, Galuppo V, De Serio D,
Surace FC, Cavaliere AL, Leone A, Coppola C, Ellison GM, Indolfi C.
Fludarabine prevents smooth muscle proliferation in vitro and neointimal
hyperplasia in vivo through specific inhibition of STAT-1 activation Am
J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2935-43. Epub 2007 Feb 9.
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| Immunology |
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Lawson BR, Manenkova Y, Ahamed J, Chen X, Zou JP, Baccala
R, Theofilopoulos AN, Yuan C. Inhibition of transmethylation
down-regulates CD4 T cell activation and curtails development of
autoimmunity in a model system. J Immunol. 2007 Apr 15;178(8):5366-74. |
PUBMED |
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Wang J, Barke RA, Charboneau R, Schwendener R, Roy S.
Morphine Induces Defects in Early Response of Alveolar Macrophages to
Streptococcus pneumoniae by Modulating TLR9-NF-{kappa}B Signaling. J
Immunol. 2008 Mar 1;180(5):3594-600. |
PUBMED |
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| Neuroscience |
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Uo T, Kinoshita Y, Morrison RS. Apoptotic actions of p53
require transcriptional activation of PUMA and do not involve a direct
mitochondrial/cytoplasmic site of action in postnatal cortical neurons J
Neurosci. 2007 Nov 7;27(45):12198-210. |
PUBMED |
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| Signal Transduction |
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Ciccone NA, Lacza CT, Hou MY, Gregory SJ, Kam KY, Xu S,
Kaiser UB. A Composite Element that Binds Basic Helix Loop Helix and
Basic Leucine Zipper Transcription Factors Is Important for GnRH
Regulation of the FSH{beta} Gene. Mol Endocrinol. 2008 Jun 11. [Epub
ahead of print] |
PUBMED |
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Xue M, Campbell D, Jackson CJ Protein C is an autocrine
growth factor for human skin keratinocytes J Biol Chem. 2007 May
4;282(18):13610-6. Epub 2007 Feb 9. |
PUBMED |
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| Stem Cells |
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Guo Y, Mantel C, Hromas RA, Broxmeyer HE Oct-4 is
critical for survival/antiapoptosis of murine embryonic stem cells
subjected to stress: effects associated with Stat3/survivin. Stem Cells.
2008 Jan;26(1):30-4. Epub 2007 Oct 11 |
PUBMED |
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Liou JY, Ellent DP, Lee S, Goldsby J, Ko BS, Matijevic N,
Huang JC, Wu KK. Cyclooxygenase-2-derived prostaglandin e2 protects
mouse embryonic stem cells from apoptosis. Stem Cells. 2007
May;25(5):1096-103. Epub 2007 Jan 18. |
PUBMED |
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Wang XY, Yin Y, Yuan H, Sakamaki T, Okano H, Glazer RI.
Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated
activation of the Wnt and Notch pathways. Mol Cell Biol. 2008
Jun;28(11):3589-99. Epub 2008 Mar 24 |
PUBMED |
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| Akt1 |
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Harada H, Itasaka S, Kizaka-Kondoh S, Shibuya K, Morinibu A, Shinomiya K, Hiraoka M. Akt/mTOR pathway assures the synthesis of HIF-1alpha protein in a glucose- and reoxygenation-dependent manner in irradiated tumors. J Biol Chem. 2008 Dec 19. [Epub ahead of print]
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PUBMED |
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| alpha-TM |
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Lange K, Kammerer M, Saupe F, Hegi ME, Grotegut S, Fluri E, Orend G. Combined lysophosphatidic acid/platelet-derived growth factor signaling triggers glioma cell migration in a tenascin-C microenvironment. Cancer Res. 2008 Sep 1;68(17):6942-52.
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PUBMED |
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| BRCAI |
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Deng C, Ueda E, Chen KE, Bula C, Norman AW, Luben RA, Walker AM Prolactin blocks nuclear translocation of VDR by regulating its interaction with BRCA1 in osteosarcoma cells Mol Endocrinol. 2009 Feb;23(2):226-36. Epub 2008 Dec 12
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PUBMED |
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| HePTP |
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McAlees JW, Sanders VM Hematopoietic protein tyrosine phosphatase mediates beta2-adrenergic receptor-induced regulation of p38 mitogen-activated protein kinase in B lymphocytes. Mol Cell Biol. 2009 Feb;29(3):675-86. Epub 2008 Dec 1
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PUBMED |
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| HRB |
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Chaineau M, Danglot L, Proux-Gillardeaux V, Galli T Role of HRB in clathrin-dependent endocytosis J Biol Chem. 2008 Dec 5;283(49):34365-73. Epub 2008 Sep 25
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PUBMED |
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| MBD2 |
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Ramachandran K, Gopisetty G, Gordian E, Navarro L, Hader C, Reis IM, Schulz WA, Singal R. Methylation-Mediated Repression of GADD45{alpha} in Prostate Cancer and Its Role as a Potential Therapeutic Target. Cancer Res. 2009 Feb 3. [Epub ahead of print]
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PUBMED |
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| MGMT |
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Zheng M, Bocangel D, Ramesh R, Ekmekcioglu S, Poindexter N, Grimm EA, Chada S Interleukin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells. Mol Cancer Ther. 2008 Dec;7(12):3842-51. Epub 2008 Dec 3
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PUBMED |
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| MMP-3, MMP-9 |
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Barkho BZ, Munoz AE, Li X, Li L, Cunningham LA, Zhao X Endogenous matrix metalloproteinase (MMP)-3 and MMP-9 promote the differentiation and migration of adult neural progenitor cells in response to chemokines. Stem Cells. 2008 Dec;26(12):3139-49. Epub 2008 Sep 25
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PUBMED |
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| Dnmt3a |
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Do JT, Han DW, Gentile L, Sobek-Klocke I, Stehling M, Sch鰈er HR. Enhanced Reprogramming of Xist by induced upregulation of Tsix and Dnmt3a. Stem Cells. 2008 Aug 28. [Epub ahead of print]
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PUBMED |
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| OSX |
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Mikami Y, Somei M, Takagi M. A New Synthetic Compound, SST-VEDI-1, Inhibits Osteoblast Differentiation with a Down-Regulation of the Osterix Expression. J Biochem. 2009 Feb;145(2):239-247. Epub 2008 Dec 8.
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PUBMED |
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| RALT |
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Cai J, Yi FF, Yang L, Shen DF, Yang Q, Li A, Ghosh AK, Bian ZY, Yan L, Tang QZ, Li H, Yang XC. Targeted Expression of Receptor-Associated Late Transducer Inhibits Maladaptive Hypertrophy via Blocking Epidermal Growth Factor Receptor Signaling. Hypertension. 2009 Feb 9. [Epub ahead of print]
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PUBMED |
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| ROR2, Wnt5a |
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DeMorrow S, Francis H, Gaudio E, Venter J, Franchitto A, Kopriva S, Onori P, Mancinelli R, Frampton G, Coufal M, Mitchell B, Vaculin B, Alpini G. The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway. Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1150-8. Epub 2008 Oct 2
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PUBMED |
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| TCF4 |
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Tang Y, Simoneau AR, Liao WX, Yi G, Hope C, Liu F, Li S, Xie J, Holcombe RF, Jurnak FA, Mercola D, Hoang BH, Zi X. WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cells. Mol Cancer Ther. 2009 Feb;8(2):458-68. Epub 2009 Jan 27
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PUBMED |
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| TRPV4 |
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Gao F, Sui D, Garavito RM, Worden RM, Wang DH. Salt intake augments hypotensive effects of transient receptor potential vanilloid 4: functional significance and implication. Hypertension. 2009 Feb;53(2):228-35. Epub 2008 Dec 15
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PUBMED |
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| Uhrf2 |
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Iwata A, Nagashima Y, Matsumoto L, Suzuki T, Yamanaka T, Date H, Deoka K, Nukina N, Tsuji S. Intra-nuclear degradation of polyglutamine aggregates by the ubiquitin proteasome system. J Biol Chem. 2009 Feb 13. [Epub ahead of print]
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PUBMED |
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| ZW10 |
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Whyte J, Bader JR, Tauhata SB, Raycroft M, Hornick J, Pfister KK, Lane WS, Chan GK, Hinchcliffe EH, Vaughan PS, Vaughan KT Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis. J Cell Biol. 2008 Dec 1;183(5):819-34. Epub 2008 Nov 24
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| BIRC5 |
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Pise-Masison CA, Radonovich M, Dohoney K, Morris JC, O'Mahony D, Lee MJ, Trepel J, Waldmann TA, Janik JE, Brady JN. Gene expression profiling of ATL patients: compilation of disease related genes and evidence for TCF-4 involvement in BIRC5 gene expression and cell viability. Blood. 2009 Jan 8. [Epub ahead of print]
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PUBMED |
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| Ppapdc3/NET39 |
| Liu GH, Guan T, Datta K, Coppinger J, Yates J 3rd, Gerace L. Regulation of myoblast differentiation by the nuclear envelope protein NET39. Mol Cell Biol. 2009 Nov;29(21):5800-12. Epub 2009 Aug 24. | PUBMED |
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| KLF5 |
| Mori A, Moser C, Lang SA, Hackl C, Gottfried E, Kreutz M, Schlitt HJ, Geissler EK, Stoeltzing O. Up-regulation of Kruppel-like factor 5 in pancreatic cancer is promoted by Mol Cancer Res. 2009 Aug;7(8):1390-8. Epub 2009 Aug 11. | PUBMED |
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| CaMKII |
| Sebeo J, Hsiao K, Bozdagi O, Dumitriu D, Ge Y, Zhou Q, Benson DL. Requirement for protein synthesis at developing synapses. J Neurosci. 2009 Aug 5;29(31):9778-93. | PUBMED |
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| PP5 |
| Zhang Y, Leung DY, Nordeen SK, Goleva E. Estrogen inhibits glucocorticoid action via protein phosphatase 5 (PP5)-mediated J Biol Chem. 2009 Sep 4;284(36):24542-52. Epub 2009 Jul 8. | PUBMED |
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| P2X7 |
| Nobbio L, Sturla L, Fiorese F, Usai C, Basile G, Moreschi I, Benvenuto F, Zocchi E, De Flora A, Schenone A, Bruzzone S. P2X7-mediated increased intracellular calcium causes functional derangement in J Biol Chem. 2009 Aug 21;284(34):23146-58. Epub 2009 Jun 22. | PUBMED |
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| PGC-1, PGC-1, and GCN5 |
| Wareski P, Vaarmann A, Choubey V, Safiulina D, Liiv J, Kuum M, Kaasik A. PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons. J Biol Chem. 2009 Aug 7;284(32):21379-85. Epub 2009 Jun 19. | PUBMED |
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| XIAP, PTEN |
| Van Themsche C, Leblanc V, Parent S, Asselin E. X-linked inhibitor of apoptosis protein (XIAP) regulates PTEN ubiquitination, J Biol Chem. 2009 Jul 31;284(31):20462-6. Epub 2009 May 27. | PUBMED |
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| Ets-1 |
| Huang TH, Wu F, Loeb GB, Hsu R, Heidersbach A, Brincat A, Horiuchi D, Lebbink RJ, Mo YY, Goga A, McManus MT. Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion. J Biol Chem. 2009 Jul 3;284(27):18515-24. Epub 2009 May 6. | PUBMED |
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| 15-LOX |
| Calandria JM, Marcheselli VL, Mukherjee PK, Uddin J, Winkler JW, Petasis NA, Bazan NG. Selective survival rescue in 15-lipoxygenase-1-deficient retinal pigment J Biol Chem. 2009 Jun 26;284(26):17877-82. Epub 2009 Apr 29. | PUBMED |
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| Annexin A6 |
| Monastyrskaya K, Babiychuk EB, Hostettler A, Wood P, Grewal T, Draeger A. Plasma membrane-associated annexin A6 reduces Ca2+ entry by stabilizing the J Biol Chem. 2009 Jun 19;284(25):17227-42. Epub 2009 Apr 22. | PUBMED |
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| ALK1, ALK5 |
| Blaney Davidson EN, Remst DF, Vitters EL, van Beuningen HM, Blom AB, Goumans MJ, van den Berg WB, van der Kraan PM. Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in J Immunol. 2009 Jun 15;182(12):7937-45. | PUBMED |
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| ERRa |
| Chisamore MJ, Wilkinson HA, Flores O, Chen JD. Estrogen-related receptor-alpha antagonist inhibits both estrogen Mol Cancer Ther. 2009 Mar;8(3):672-81. Epub 2009 Mar 10. | PUBMED |
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| CypD |
| Eliseev RA, Malecki J, Lester T, Zhang Y, Humphrey J, Gunter TE. Cyclophilin D interacts with Bcl2 and exerts an anti-apoptotic effect. J Biol Chem. 2009 Apr 10;284(15):9692-9. Epub 2009 Feb 19. | PUBMED |
| | |
| E2F7 |
| Endo-Munoz L, Dahler A, Teakle N, Rickwood D, Hazar-Rethinam M, Abdul-Jabbar I, Sommerville S, Dickinson I, Kaur P, Paquet-Fifield S, Saunders N. E2F7 can regulate proliferation, differentiation, and apoptotic responses in Cancer Res. 2009 Mar 1;69(5):1800-8. Epub 2009 Feb 17. | PUBMED |
| | |
| Megf8 |
| Zhang Z, Alpert D, Francis R, Chatterjee B, Yu Q, Tansey T, Sabol SL, Cui C, Bai Y, Koriabine M, Yoshinaga Y, Cheng JF, Chen F, Martin J, Schackwitz W, Gunn TM, Kramer KL, De Jong PJ, Pennacchio LA, Lo CW. Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3219-24. Epub 2009 Feb 13. | PUBMED |
| | |
| Uhrf2 |
| Iwata A, Nagashima Y, Matsumoto L, Suzuki T, Yamanaka T, Date H, Deoka K, Nukina N, Tsuji S. Intranuclear degradation of polyglutamine aggregates by the ubiquitin-proteasome J Biol Chem. 2009 Apr 10;284(15):9796-803. Epub 2009 Feb 13. | PUBMED |
| | |
| PPARgamma |
| Ghosh AK, Bhattacharyya S, Wei J, Kim S, Barak Y, Mori Y, Varga J. Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent FASEB J. 2009 Sep;23(9):2968-77. Epub 2009 Apr 24. | PUBMED |
| | |
| Rab11a and Rab11b |
| Silvis MR, Bertrand CA, Ameen N, Golin-Bisello F, Butterworth MB, Frizzell RA, Bradbury NA. Rab11b regulates the apical recycling of the cystic fibrosis transmembrane Mol Biol Cell. 2009 Apr;20(8):2337-50. Epub 2009 Feb 25. | PUBMED |
| | |
| Caveolin-1 |
| Liao WX, Feng L, Zhang H, Zheng J, Moore TR, Chen DB. Compartmentalizing VEGF-induced ERK2/1 signaling in placental artery endothelial Mol Endocrinol. 2009 Sep;23(9):1428-44. Epub 2009 May 28. | PUBMED |
BACK TO TOP
RT² miRNA PCR Arrays
| miR-33 |
| Rayner KJ, Suárez Y, Dávalos A,
Parathath S, Fitzgerald ML, Tamehiro N, Fisher EA, Moore KJ, Fernández-Hernando
C.
MiR-33 Contributes to the Regulation of Cholesterol Homeostasis Science.
2010 Jun 18;328(5985):1570-3 | Detail |
| | |
| miR-382 |
| Alison J. Kriegel, Yi Fang, Yong Liu,
Zhongmin Tian, Domagoj Mladinov, Isaac R. Matus, Xiaoqiang Ding,
Andrew S. Greene, and Mingyu Liang MicroRNA-target pairs in human
renal epithelial cells treated with transforming growth factor β1: a
novel role of miR-382 RNA: Nucleic Acids Res., Aug 2010; 10.1093/nar/gkq718. | Detail |
| | |
| Biomarker |
| Philippidou D, Schmitt M, Moser D,
Margue C, Nazarov PV, Muller A, Vallar L, Nashan D, Behrmann I, Kreis S.
Signatures of microRNAs and selected microRNA target genes in human
melanoma. TUMOR AND STEM CELL BIOLOGY: Cancer Res., May 2010; 70: 4163 -
4173. | Detail |
| | |
| miR-24 |
| Liao WX, Feng L, Zhang H, Zheng J, Moore
TR, Chen DB. Compartmentalizing VEGF-induced ERK2/1 signaling in
placental artery endothelial Mol Endocrinol. 2009 Sep;23(9):1428-44.
Epub 2009 May 28.
PUBMED | PUBMED |
| | |
| miR-25 |
| Kuhn AR, Schlauch K, Lao R, Halayko AJ,
Gerthoffer WT, Singer CA. MicroRNA Expression in Human Airway Smooth
Muscle Cells: Role of miR-25 in Regulation of Airway Smooth Muscle
Phenotype Am J Respir Cell Mol Biol. 2010 Apr;42(4):506-13. | PUBMED |
BACK TO TOP
RT² PCR Primer Sets
|
Acuff HB, Sinnamon M, Fingleton B, Boone B,
Levy SE, Chen X, Pozzi A, Carbone DP, Schwartz DR, Moin K, Sloane BF,
Matrisian LM. Analysis of host- and tumor-derived proteinases using a
custom dual species microarray reveals a protective role for stromal
matrix metalloproteinase-12 in non-small cell lung cancer. Cancer Res.
2006 Aug 15;66(16):7968-75. |
PUBMED |
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Albanesi C, Fairchild HR, Madonna S, Scarponi
C, De Pit?O, Leung DY, Howell MD. IL-4 and IL-13 negatively regulate TNF-alpha-
and IFN-gamma-induced beta-defensin expression through STAT-6,
suppressor of cytokine signaling (SOCS)-1, and SOCS-3. J Immunol. 2007
Jul 15;179(2):984-92 |
PUBMED |
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Alikhani M, Alikhani Z, Graves DT. FOXO1
functions as a master switch that regulates gene expression necessary
for tumor necrosis factor-induced fibroblast apoptosis. J Biol Chem.
2005 Apr 1;280(13):12096-102. Epub 2005 Jan 4. |
PUBMED |
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Andarawewa KL, Erickson AC, Chou WS, Costes
SV, Gascard P, Mott JD, Bissell MJ, Barcellos-Hoff MH. Ionizing
radiation predisposes nonmalignant human mammary epithelial cells to
undergo transforming growth factor beta induced epithelial to
mesenchymal transition. Cancer Res. 2007 Sep 15;67(18):8662-70. |
PUBMED |
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Angeloni C, Leoncini E, Malaguti M, Angelini S, Hrelia P,
Hrelia S. Role of quercetin in modulating rat cardiomyocyte gene
expression profile Am J Physiol Heart Circ Physiol. 2008
Mar;294(3):H1233-43. Epub 2008 Jan 4 |
PUBMED |
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Artaza JN, Singh R, Ferrini MG, Braga M, Tsao J,
Gonzalez-Cadavid NF Myostatin promotes a fibrotic phenotypic switch in
multipotent C3H 10T1/2 cells without affecting their differentiation
into myofibroblasts J Endocrinol. 2008 Feb;196(2):235-49
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PUBMED |
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Asprodites N, Zheng L, Geng D, Velasco-Gonzalez C,
Sanchez-Perez L, Davila E. Engagement of Toll-like receptor-2 on
cytotoxic T-lymphocytes occurs in vivo and augments antitumor activity.
FASEB J. 2008 Jun 27. [Epub ahead of print] |
PUBMED |
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Augustus AS, Buchanan J, Addya S, Rengo G, Pestell R,
Fortina P, Koch WJ, Bensadoun A, Abel ED, Lisanti MP. Substrate Uptake
and Metabolism are Preserved in Hypertrophic Caveolin-3 Knockout Hearts.
Am J Physiol Heart Circ Physiol. 2008 Jun 13. [Epub ahead of print] |
PUBMED |
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Beinfeld MC, Blum A, Vishnuvardhan D, Fanous
S, Marchand JE Cholecystokinin levels in prohormone convertase 2
knock-out mouse brain regions reveal a complex phenotype of
region-specific alterations J Biol Chem. 2005 Nov 18;280(46):38410-5.
Epub 2005 Sep 20 |
PUBMED |
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Beretsos P, Loutradis D, Koussoulakos S,
Margaritis LH, Kiapekou E, Mastorakos G, Papaspirou I, Makris N,
Makrigiannakis A, Antsaklis A. Oxytocin receptor is differentially
expressed in mouse endometrium and embryo during blastocyst
implantation. Ann N Y Acad Sci. 2006 Dec;1092:466-79. |
PUBMED |
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Binnerts ME, Kim KA, Bright JM, Patel SM,
Tran K, Zhou M, Leung JM, Liu Y, Lomas WE 3rd, Dixon M, Hazell SA, Wagle
M, Nie WS, Tomasevic N, Williams J, Zhan X, Levy MD, Funk WD, Abo A.
R-Spondin1 regulates Wnt signaling by inhibiting internalization of
LRP6. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14700-5. Epub 2007
Sep 5 |
PUBMED |
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Bird AD, Tan KH, Olsson PF, Zieba M, Flecknoe
SJ, Liddicoat DR, Mollard R, Hooper SB, Cole TJ. Identification of
glucocorticoid-regulated genes that control cell proliferation during
murine respiratory development. J Physiol. 2007 Nov 15;585(Pt
1):187-201. Epub 2007 Sep 27 |
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Boer B, Kopp J, Mallanna S, Desler M,
Chakravarthy H, Wilder PJ, Bernadt C, Rizzino A. Elevating the levels of
Sox2 in embryonal carcinoma cells and embryonic stem cells inhibits the
expression of Sox2:Oct-3/4 target genes. Nucleic Acids Res.
2007;35(6):1773-86. Epub 2007 Feb 25 |
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Bossard C, Bresson D, Polishchuk RS, Malhotra V. Dimeric
PKD regulates membrane fission to form transport carriers at the TGN. J
Cell Biol. 2007 Dec 17;179(6):1123-31. |
PUBMED |
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Brandl K, Plitas G, Schnabl B, DeMatteo RP,
Pamer EG. MyD88-mediated signals induce the bactericidal lectin RegIII
gamma and protect mice against intestinal Listeria monocytogenes
infection. J Exp Med. 2007 Aug 6;204(8):1891-900. Epub 2007 Jul 16 |
PUBMED |
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Brest P, Gustafsson M, Mossberg AK, Gustafsson L,
Duringer C, Hamiche A, Svanborg C. Histone deacetylase inhibitors
promote the tumoricidal effect of HAMLET. Cancer Res. 2007 Dec
1;67(23):11327-34 |
PUBMED |
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Brown JM, Swindle EJ, Kushnir-Sukhov NM,
Holian A, Metcalfe DD. Silica-Directed Mast Cell Activation Is Enhanced
by Scavenger Receptors. Am J Respir Cell Mol Biol. 2007 Jan;36(1):43-52.
Epub 2006 Aug 10 |
PUBMED |
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Burgess SJ, Marusina AI, Pathmanathan I,
Borrego F, Coligan JE IL-21 Down-Regulates NKG2D/DAP10 Expression on
Human NK and CD8+ T Cells J Immunol. 2006 Feb 1;176(3):1490-7 |
PUBMED |
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Chen S, Sims GP, Chen XX, Gu YY, Chen S,
Lipsky PE. Modulatory effects of 1,25-dihydroxyvitamin D3 on human B
cell differentiation. J Immunol. 2007 Aug 1;179(3):1634-47 |
PUBMED |
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Cheng W, Jacobs WB, Zhang JJ, Moro A, Park JH,
Kushida M, Qiu W, Mills AA, Kim PC. DeltaNp63 plays an anti-apoptotic
role in ventral bladder development. Development. 2006
Dec;133(23):4783-92. Epub 2006 Nov 1. |
PUBMED |
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Chiao E, Elazar M, Xing Y, Xiong A, Kmet M, Millan MT,
Glenn JS, Wong WH, Baker J. Isolation and Transcriptional Profiling of
Purified Hepatic Cells Derived from Human Embryonic Stem Cells. Stem
Cells. 2008 Jun 5. [Epub ahead of print] |
PUBMED |
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Crossno JT Jr, Majka SM, Grazia T, Gill RG,
Klemm DJ. Rosiglitazone promotes development of a novel adipocyte
population from bone marrow-derived circulating progenitor cells. J Clin
Invest. 2006 Dec;116(12):3220-8 |
PUBMED |
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Dai J, Hall CL, Escara-Wilke J, Mizokami A, Keller JM,
Keller ET. Prostate cancer induces bone metastasis through Wnt-induced
bone morphogenetic protein-dependent and independent mechanisms. Cancer
Res. 2008 Jul 15;68(14):5785-94. |
PUBMED |
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Datta A, Sinha-Datta U, Dhillon NK, Buch S,
Nicot C. The HTLV-I p30 Interferes with TLR4 Signaling and Modulates the
Release of Pro- and Anti-inflammatory Cytokines from Human Macrophages.
J Biol Chem. 2006 Aug 18;281(33):23414-24. Epub 2006 Jun 19. |
PUBMED |
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Demorrow S, Francis H, Gaudio E, Ueno Y, Venter J, Onori
P, Franchitto A, Vaculin B, Vaculin S, Alpini G Anandamide inhibits
cholangiocyte hyperplastic proliferation via activation of thioredoxin
1/redox factor 1 and AP-1 activation. Am J Physiol Gastrointest Liver
Physiol. 2007 Dec 20 [Epub ahead of print] |
PUBMED |
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DeMorrow S, Glaser S, Francis H, Venter J,
Vaculin B, Vaculin S, Alpini G Opposing actions of endocannabinoids on
cholangiocarcinoma growth: recruitment of Fas and Fas ligand to lipid
rafts. J Biol Chem. 2007 Apr 27;282(17):13098-113. Epub 2007 Feb 28 |
PUBMED |
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Dhillon NK, Peng F, Ransohoff RM, Buch S PDGF
synergistically enhances IFN-gamma-induced expression of CXCL10 in
blood-derived macrophages: implications for HIV dementia. J Immunol.
2007 Sep 1;179(5):2722-30 |
PUBMED |
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Dimitrijevic OB, Stamatovic SM, Keep RF,
Andjelkovic AV Absence of the chemokine receptor CCR2 protects against
cerebral ischemia/reperfusion injury in mice. Stroke. 2007
Apr;38(4):1345-53. Epub 2007 Mar 1 |
PUBMED |
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Dominguez J, Wu P, Packer CS, Temm C, Kelly
KJ. Lipotoxic and inflammatory phenotypes in rats with uncontrolled
metabolic syndrome and nephropathy. Am J Physiol Renal Physiol. 2007
Sep;293(3):F670-9. Epub 2007 Jun 27 |
PUBMED |
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Drew JE, Farquharson AJ, Padidar S, Duthie GG,
Mercer JG, Arthur JR, Morrice PC, Barrera LN. Insulin, leptin, and
adiponectin receptors in colon: regulation relative to differing body
adiposity independent of diet and in response to dimethylhydrazine. Am J
Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G682-91. Epub 2007
Jul 26 |
PUBMED |
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Emmons J, Townley-Tilson WH, Deleault KM, Skinner SJ,
Gross RH, Whitfield ML, Brooks SA Identification of TTP mRNA targets in
human dendritic cells reveals TTP as a critical regulator of dendritic
cell maturation. RNA. 2008 May;14(5):888-902. Epub 2008 Mar 26. |
PUBMED |
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Enshell-Seijffers D, Lindon C, Morgan BA. The serine
protease Corin is a novel modifier of the agouti pathway. Development.
2008 Jan;135(2):217-25. Epub 2007 Dec 5 |
PUBMED |
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Fang CH, Li B, James JH, Yahya A, Kadeer N,
Guo X, Xiao C, Supp DM, Kagan RJ, Hasselgren PO, Sheriff S. GSK-3beta
activity is increased in skeletal muscle after burn injury in rats. Am J
Physiol Regul Integr Comp Physiol. 2007 Oct;293(4):R1545-51. Epub 2007
Aug 8 |
PUBMED |
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Fang J, Menon M, Kapelle W, Bogacheva O,
Bogachev O, Houde E, Browne S, Sathyanarayana P, Wojchowski DM EPO
modulation of cell-cycle regulatory genes, and cell division, in primary
bone marrow erythroblasts. Blood. 2007 Oct 1;110(7):2361-70. Epub 2007
Jun 4 |
PUBMED |
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Ferron M, Hinoi E, Karsenty G, Ducy P. Osteocalcin
differentially regulates beta cell and adipocyte gene expression and
affects the development of metabolic diseases in wild-type mice. Proc
Natl Acad Sci U S A. 2008 Apr 1;105(13):5266-70. Epub 2008 Mar 24. |
PUBMED |
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Forbes EE, Groschwitz K, Abonia JP, Brandt EB, Cohen E,
Blanchard C, Ahrens R, Seidu L, McKenzie A, Strait R, Finkelman FD,
Foster PS, Matthaei KI, Rothenberg ME, Hogan SP IL-9- and mast
cell-mediated intestinal permeability predisposes to oral antigen
hypersensitivity. J Exp Med. 2008 Apr 14;205(4):897-913. Epub 2008 Mar
31 |
PUBMED |
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Franchi A, Zaret J, Zhang X, Bocca S, Oehninger S.
Expression of immunomodulatory genes and their ligands/receptors during
the window of implantation in human endometrium. Mol Hum Reprod. 2008
Jun 4. [Epub ahead of print] |
PUBMED |
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Fujiwara K, Daido S, Yamamoto A, Kobayashi R,
Yokoyama T, Aoki H, Iwado E, Shinojima N, Kondo Y, Kondo S. Pivotal role
of the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in apoptosis and
autophagy. J Biol Chem. 2007 Oct 24; [Epub ahead of print] |
PUBMED |
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Glaser S, Demorrow S, Francis H, Ueno Y, Gaudio E,
Vaculin S, Venter J, Franchitto A, Onori P, Vaculin B, Marzioni M, Wise
C, Pilanthananond M, Savage J, Pierce L, Mancinelli R, Alpini G.
Progesterone stimulates the proliferation of female and male
cholangiocytes via autocrine/paracrine mechanisms. Am J Physiol
Gastrointest Liver Physiol. 2008 Jul;295(1):G124-G136. Epub 2008 May
29. |
PUBMED |
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Grigore D, Ojeda NB, Robertson EB, Dawson AS,
Huffman CA, Bourassa EA, Speth RC, Brosnihan KB, Alexander BT. Placental
insufficiency results in temporal alterations in the renin angiotensin
system in male hypertensive growth restricted offspring. Am J Physiol
Regul Integr Comp Physiol. 2007 Aug;293(2):R804-11. Epub 2007 May 30 |
PUBMED |
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Guo Y, Mantel C, Hromas RA, Broxmeyer HE. Oct
4 is Critical for Survival/Antiapoptosis of Murine Embryonic Stem Cells
Subjected to Stress. Effects Associated with STAT3/Survivin. Stem Cells.
2007 Oct 11; [Epub ahead of print] |
PUBMED |
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Hamill CE, Caudle WM, Richardson JR, Yuan H,
Pennell KD, Greene JG, Miller GW, Traynelis SF. Exacerbation of
dopaminergic terminal damage in a mouse model of Parkinson's disease by
the G-protein-coupled receptor protease-activated receptor 1. Mol
Pharmacol. 2007 Sep;72(3):653-64. Epub 2007 Jun 27 |
PUBMED |
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Hamilton KL, Lin L, Wang Y, Knowlton AA.
Effect of Ovariectomy on Cardiac Gene Expression: Inflammation and
Changes in SOCS Genes Expression Physiol Genomics. 2007 Nov 6; [Epub
ahead of print] |
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Hirbe AC, Rubin J, Uluçan O, Morgan
EA, Eagleton MC, Prior JL, Piwnica-Worms D, Weilbaecher KN. Disruption
of CXCR4 enhances osteoclastogenesis and tumor growth in bone. Proc Natl
Acad Sci U S A. 2007 Aug 28;104(35):14062-7. Epub 2007 Aug 22. |
PUBMED |
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Hooks JJ, Nagineni CN, Hooper LC, Hayashi K, Detrick B.
IFN-beta provides immuno-protection in the retina by inhibiting ICAM-1
and CXCL9 in retinal pigment epithelial cells J Immunol. 2008 Mar
15;180(6):3789-96 |
PUBMED |
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Hsu S, Dickinson DP, Qin H, Lapp C, Lapp D, Borke J,
Walsh DS, Bollag WB, Stoppler H, Yamamoto T, Osaki T, Schuster G
Inhibition of autoantigen expression by (-)-epigallocatechin-3-gallate
(the major constituent of green tea) in normal human cells. J Pharmacol
Exp Ther. 2005 Nov;315(2):805-11. Epub 2005 Jul 26. |
PUBMED |
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Hu YF, Zhang ZJ, Sieber-Blum M An epidermal
neural crest stem cell (EPI-NCSC) molecular signature. Stem Cells. 2006
Dec;24(12):2692-702. Epub 2006 Aug 24 |
PUBMED |
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Jiao J, Wang S, Qiao R, Vivanco I, Watson PA,
Sawyers CL, Wu H. Murine cell lines derived from Pten null prostate
cancer show the critical role of PTEN in hormone refractory prostate
cancer development Cancer Res. 2007 Jul 1;67(13):6083-91 |
PUBMED |
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Jones RA, Campbell CI, Petrik JJ, Moorehead RA
Characterization of a Novel Primary Mammary Tumor Cell Line Reveals that
Cyclin D1 Is Regulated by the Type I Insulin-Like Growth Factor
Receptor. Mol Cancer Res. 2008 May;6(5):819-28 |
PUBMED |
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Kafienah W, Mistry S, Perry MJ, Politopoulou
G, Hollander AP Pharmacological regulation of adult stem cells:
chondrogenesis can be induced using a synthetic inhibitor of the
retinoic acid receptor Stem Cells. 2007 Oct;25(10):2460-8. Epub 2007 Jul
5 |
PUBMED |
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Kim J, Jahng WJ, Di Vizio D, Lee JS, Jhaveri
R, Rubin MA, Shisheva A, Freeman MR. The phosphoinositide kinase PIKfyve
mediates epidermal growth factor receptor trafficking to the nucleus.
Cancer Res. 2007 Oct 1;67(19):9229-37 |
PUBMED |
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Kline ER, Kleinhenz DJ, Liang B, Dikalov S, Guidot DM,
Hart CM, Jones DP, Sutliff RL. Vascular oxidative stress and nitric
oxide depletion in HIV-1 transgenic rats are reversed by glutathione
restoration. Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2792-804.
Epub 2008 May 2. |
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Kreslavsky T, Garbe AI, Krueger A, von Boehmer H T cell
receptor-instructed {alpha}{beta} versus {gamma}{delta} lineage
commitment revealed by single-cell analysis. J Exp Med. 2008 May
12;205(5):1173-86. Epub 2008 Apr 28. |
PUBMED |
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Kuznetsov AV, Smigelskaite J, Doblander C, Janakiraman M,
Hermann M, Wurm M, Scheidl SF, Sucher R, Deutschmann A, Troppmair J.
Survival signaling by C-RAF: mitochondrial reactive oxygen species and
Ca2+ are critical targets. Mol Cell Biol. 2008 Apr;28(7):2304-13. Epub
2008 Jan 22 |
PUBMED |
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Larson JE, Cohen JC "Improvement of
pulmonary hypoplasia associated with congenital diaphragmatic hernia by
in utero CFTR gene therapy. Am J Physiol Lung Cell Mol Physiol. 2006
Jul;291(1):L4-L10. Epub 2006 Feb 10. |
PUBMED |
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Lee JK, Mathew SO, Vaidya SV, Kumaresan PR,
Mathew PA. CS1 (CRACC, CD319) induces proliferation and autocrine
cytokine expression on human B lymphocytes. J Immunol. 2007 Oct
1;179(7):4672-8 |
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Li S, Nikulina K, DeVoss J, Wu AJ, Strauss EC, Anderson
MS, McNamara NA. Small proline-rich protein 1B (SPRR1B) is a biomarker
for squamous metaplasia in dry eye disease. Invest Ophthalmol Vis Sci.
2008 Jan;49(1):34-41. |
PUBMED |
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Li Y, Mezei O, Shay NF. Human and murine
hepatic sterol-12-alpha-hydroxylase and other xenobiotic metabolism mRNA
are upregulated by soy isoflavones. J Nutr. 2007 Jul;137(7):1705-12. |
PUBMED |
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Li Z, Mahesh SP, Shen de F, Liu B, Siu WO,
Hwang FS, Wang QC, Chan CC, Pastan I, Nussenblatt RB. Eradication of
tumor colonization and invasion by a B cell-specific immunotoxin in a
murine model for human primary intraocular lymphoma. Cancer Res. 2006
Nov 1;66(21):10586-93. |
PUBMED |
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Lian X, Qin Y, Hossain SA, Yang L, White A,
Xu H, Shipley JM, Li T, Senior RM, Du H, Yan C. Overexpression of Stat3C
in Pulmonary Epithelium Protects against Hyperoxic Lung Injury. J
Immunol. 2005 Jun 1;174(11):7250-7256. |
PUBMED |
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Lindemann MJ, Hu Z, Benczik M, Liu KD, Gaffen SL
Differential Regulation of the IL-17 Receptor by {gamma}c Cytokines:
INHIBITORY SIGNALING BY THE PHOSPHATIDYLINOSITOL 3-KINASE PATHWAY. J
Biol Chem. 2008 May 16;283(20):14100-8. Epub 2008 Mar 17 |
PUBMED |
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Linder AE, Ni W, Szasz T, Burnett R, Diaz J, Geddes TJ,
Kuhn DM, Watts SW A serotonergic system in veins: serotonin
transporter-independent uptake J Pharmacol Exp Ther. 2008
Jun;325(3):714-22. Epub 2008 Mar 5 |
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Liu J, Hamrouni A, Wolowiec D, Coiteux V,
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Low K, Culbertson M, Bradke F, Tessier-Lavigne M,
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Lowry MH, McAllister BP, Jean JC, Brown LS, Hughey RP,
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Megias J, Guillen MI, Bru A, Gomar F, Alcaraz
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Meyer-Siegler KL, Iczkowski KA, Leng L,
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Mezei O, Li Y, Mullen E, Ross-Viola JS, Shay
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Monroe DG, Secreto FJ, Subramaniam M, Getz BJ,
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Motiwala AS, Janagama HK, Paustian ML, Zhu X,
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Murphy TR, Legere HJ 3rd, Katz HR Activation
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Nam JS, Kang MJ, Suchar AM, Shimamura T, Kohn
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Nam JS, Terabe M, Kang MJ, Chae H, Voong N, Yang YA,
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Navedo MF, Nieves-Cintron M, Amberg GC, Yuan C,
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Nestor MW, Mok LP, Tulapurkar ME, Thompson
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Ni W, Fink GD, Watts SW. The
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Niculescu MD, da Costa KA, Fischer LM, Zeisel
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Ojeda NB, Grigore D, Robertson EB, Alexander
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Pandey J, Umphress SM, Kang Y, Angdisen J, Naumova A,
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Paruchuri S, Jiang Y, Feng C, Francis SA, Plutzky J,
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Peyrou M, Hanna PE, Cribb AE. Cisplatin,
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Qin S, Liu T, Kamanna VS, Kashyap ML
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Rajendram R, Saraswathy S, Rao NA.
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Rao NA, Saraswathy S, Wu GS, Katselis GS, Wawrousek EF,
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Reen RK, Dombkowski AA, Kresty LA, Cukovic D,
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Sadun RE, Sachsman SM, Chen X, Christenson
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Saha A, Hammond CE, Trojanowska M, Smolka AJ.
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Sama MA, Mathis DM, Furman JL, Mohmmad Abdul H, Artiushin
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Sathyanarayana P, Menon MP, Bogacheva O,
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Sawiris GP, Becker KG, Elliott EJ, Moulden R,
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Schenke-Layland K, Angelis E, Rhodes KE,
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Schiffer L, Bethunaickan R, Ramanujam M, Huang W,
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Sebastian T, Malik R, Thomas S, Sage J,
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Secchiero P, Corallini F, Rimondi E,
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Shen CH, Ge Q, Talay O, Eisen HN, Garc?-Sastre A, Chen
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Shi T, Duan ZH, Papay R, Pluskota E, Gaivin
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Shukla A, Ho Y, Liu X, Ryscavage A, Glick AB Cripto-1
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Singh PK, Behrens ME, Eggers JP, Cerny RL, Bailey JM,
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Sun HD, Malabunga M, Tonra JR, Direnzo R,
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Tongers J, Knapp JM, Korf M, Kempf T, Limbourg A,
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Tuo J, Bojanowski CM, Zhou M, Shen D, Ross
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Watkins SK, Egilmez NK, Suttles J, Stout RD.
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Yang L, Wang L, Kalfa T, Cancelas JA, Shang
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Zhang Y, Andl T, Yang SH, Teta M, Liu F, Seykora JT,
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Dakhova O, O'Day D, Kinet N, Yucer N, Wiese M, Shetty G, Ducy P. Dickkopf-like1 regulates postpubertal spermatocyte apoptosis and testosterone production. Endocrinology. 2009 Jan;150(1):404-12. Epub 2008 Sep 25
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Jain S, Vinukonda G, Fiering SN, Kumar A A haplotype of human angiotensinogen gene containing -217A increases blood pressure in transgenic mice compared with -217G. Am J Physiol Regul Integr Comp Physiol. 2008 Dec;295(6):R1849-57. Epub 2008 Oct 22
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DeMorrow S, Francis H, Gaudio E, Venter J, Franchitto A, Kopriva S, Onori P, Mancinelli R, Frampton G, Coufal M, Mitchell B, Vaculin B, Alpini G. The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway. Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1150-8. Epub 2008 Oct 2
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Bian ZM, Elner SG, Elner VM. Regulated expression of caspase-12 gene in human retinal pigment epithelial cells suggests its immunomodulating role. Invest Ophthalmol Vis Sci. 2008 Dec;49(12):5593-601. Epub 2008 Sep 12
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Alpini G, Invernizzi P, Gaudio E, Venter J, Kopriva S, Bernuzzi F, Onori P, Franchitto A, Coufal M, Frampton G, Alvaro D, Lee SP, Marzioni M, Benedetti A, DeMorrow S Serotonin metabolism is dysregulated in cholangiocarcinoma, which has implications for tumor growth Cancer Res. 2008 Nov 15;68(22):9184-93
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Kinney CM, Chandrasekharan UM, Yang L, Shen J, Kinter M, McDermott MS, Dicorleto PE Histone H3 as a novel substrate for MAP kinase phosphatase-1. Am J Physiol Cell Physiol. 2009 Feb;296(2):C242-9. Epub 2008 Nov 19.
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Izem L, Morton RE. Molecular cloning of hamster lipid transfer inhibitor protein (apolipoprotein F) and regulation of its expression by hyperlipidemia. J Lipid Res. 2008 Nov 13. [Epub ahead of print]
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Bafna S, Singh AP, Moniaux N, Eudy JD, Meza JL, Batra SK. MUC4, a multifunctional transmembrane glycoprotein, induces oncogenic transformation of NIH3T3 mouse fibroblast cells. Cancer Res. 2008 Nov 15;68(22):9231-8
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Ch閞et C, Gervais A, Lelli A, Colin C, Amar L, Ravassard P, Mallet J, Cumano A, Krause KH, Mallat M. Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase. J Neurosci. 2008 Nov 12;28(46):12039-51
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Venkatesan N, Barr?L, Magdalou J, Mainard D, Netter P, Fournel-Gigleux S, Ouzzine M. Modulation of xylosyltransferase I expression provides a mechanism regulating glycosaminoglycan chain synthesis during cartilage destruction and repair. FASEB J. 2008 Nov 10. [Epub ahead of print]
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Su G, Blaine SA, Qiao D, Friedl A. Membrane type 1 matrix metalloproteinase-mediated stromal syndecan-1 shedding stimulates breast carcinoma cell proliferation. Cancer Res. 2008 Nov 15;68(22):9558-65
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Gobejishvili L, Barve S, Joshi-Barve S, McClain C Enhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease. Am J Physiol Gastrointest Liver Physiol. 2008 Oct;295(4):G718-24. Epub 2008 Aug 7.
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Nieves-Cintr髇 M, Amberg GC, Navedo MF, Molkentin JD, Santana LF. The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15623-8. Epub 2008 Oct 1
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Nguyen KD, Fohner A, Booker JD, Dong C, Krensky AM, Nadeau KC. XCL1 enhances regulatory activities of CD4+ CD25(high) CD127(low/-) T cells in human allergic asthma. J Immunol. 2008 Oct 15;181(8):5386-95.
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Lovren F, Pan Y, Quan A, Teoh H, Wang G, Shukla PC, Levitt KS, Oudit GY, Al-Omran M, Stewart DJ, Slutsky AS, Peterson MD, Backx PH, Penninger JM, Verma S. Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis. Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1377-84. Epub 2008 Jul 25
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Landgren H, Blixt A, Carlsson P Persistent FoxE3 expression blocks cytoskeletal remodeling and organelle degradation during lens fiber differentiation. Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4269-77. Epub 2008 Jun 6
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Asprodites N, Zheng L, Geng D, Velasco-Gonzalez C, Sanchez-Perez L, Davila E. Engagement of Toll-like receptor-2 on cytotoxic T-lymphocytes occurs in vivo and augments antitumor activity. FASEB J. 2008 Oct;22(10):3628-37. Epub 2008 Jun 27
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Singh PK, Behrens ME, Eggers JP, Cerny RL, Bailey JM, Shanmugam K, Gendler SJ, Bennett EP, Hollingsworth MA Phosphorylation of MUC1 by Met modulates interaction with p53 and MMP1 expression. J Biol Chem. 2008 Oct 3;283(40):26985-95. Epub 2008 Jul 14.
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Nawrocki ST, Carew JS, Maclean KH, Courage JF, Huang P, Houghton JA, Cleveland JL, Giles FJ, McConkey DJ. Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA. Blood. 2008 Oct 1;112(7):2917-26. Epub 2008 Jul 18
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Conti HR, Shen F, Nayyar N, Stocum E, Sun JN, Lindemann MJ, Ho AW, Hai JH, Yu JJ, Jung JW, Filler SG, Masso-Welch P, Edgerton M, Gaffen SL. Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. J Exp Med. 2009 Feb 9. [Epub ahead of print]
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Conti HR, Shen F, Nayyar N, Stocum E, Sun JN, Lindemann MJ, Ho AW, Hai JH, Yu JJ, Jung JW, Filler SG, Masso-Welch P, Edgerton M, Gaffen SL. Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis. J Exp Med. 2009 Feb 9. [Epub ahead of print]
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Robinson K, Kenefeck R, Pidgeon EL, Shakib S, Patel S, Polson RJ, Zaitoun AM, Atherton JC. Helicobacter pylori-induced peptic ulcer disease is associated with inadequate regulatory T cell responses. Gut. 2008 Oct;57(10):1375-85. Epub 2008 May 8.
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Fischer J, Suire C, Hale-Donze H. Toll-like receptor 2 recognition of the microsporidia Encephalitozoon spp. induces nuclear translocation of NF-kappaB and subsequent inflammatory responses. Infect Immun. 2008 Oct;76(10):4737-44. Epub 2008 Aug 4.
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Fischer J, Suire C, Hale-Donze H. Toll-like receptor 2 recognition of the microsporidia Encephalitozoon spp. induces nuclear translocation of NF-kappaB and subsequent inflammatory responses. Infect Immun. 2008 Oct;76(10):4737-44. Epub 2008 Aug 4.
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Rappa G, Fodstad O, Lorico A. The stem cell-associated antigen CD133 (Prominin-1) is a Molecular Therapeutic Target for Metastatic Melanoma. Stem Cells. 2008 Sep 18. [Epub ahead of print]
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Kryczek I, Bruce AT, Gudjonsson JE, Johnston A, Aphale A, Vatan L, Szeliga W, Wang Y, Liu Y, Welling TH, Elder JT, Zou W. Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis. J Immunol. 2008 Oct 1;181(7):4733-41.
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Babbin BA, Laukoetter MG, Nava P, Koch S, Lee WY, Capaldo CT, Peatman E, Severson EA, Flower RJ, Perretti M, Parkos CA, Nusrat A. Annexin A1 regulates intestinal mucosal injury, inflammation, and repair. J Immunol. 2008 Oct 1;181(7):5035-44.
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Kihara Y, Yanagida K, Masago K, Kita Y, Hishikawa D, Shindou H, Ishii S, Shimizu T. Platelet-activating factor production in the spinal cord of experimental allergic encephalomyelitis mice via the group IVA cytosolic phospholipase A2-lyso-PAFAT axis. J Immunol. 2008 Oct 1;181(7):5008-14.
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Lee HH, Hoeman CM, Hardaway JC, Guloglu FB, Ellis JS, Jain R, Divekar R, Tartar DM, Haymaker CL, Zaghouani H. Delayed maturation of an IL-12-producing dendritic cell subset explains the early Th2 bias in neonatal immunity. J Exp Med. 2008 Sep 29;205(10):2269-80. Epub 2008 Sep 1.
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| Buchner M, Fuchs S, Prinz G, Pfeifer D, Bartholome K, Burger M, Chevalier N, Vallat L, Timmer J, Gribben JG, Jumaa H, Veelken H, Dierks C, Zirlik K. Spleen tyrosine kinase is overexpressed and represents a potential therapeutic Cancer Res. 2009 Jul 1;69(13):5424-32. Epub 2009 Jun 23. | PUBMED |
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| Block K, Gorin Y, Abboud HE. Subcellular localization of Nox4 and regulation in diabetes. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14385-90. Epub 2009 Aug 17. | PUBMED |
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| Song L, Li Y, Wang K, Wang YZ, Molotkov A, Gao L, Zhao T, Yamagami T, Wang Y, Gan Q, Pleasure DE, Zhou CJ. Lrp6-mediated canonical Wnt signaling is required for lip formation and fusion. Development. 2009 Sep;136(18):3161-71. | PUBMED |
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| Cabelof DC, Patel HV, Chen Q, van Remmen H, Matherly LH, Ge Y, Taub JW. Mutational spectrum at GATA1 provides insights into mutagenesis and Blood. 2009 Sep 24;114(13):2753-63. Epub 2009 Jul 24. | PUBMED |
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| Bexfield NA, Parcell AC, Nelson WB, Foote KM, Mack GW. Adaptations to high-intensity intermittent exercise in rodents. J Appl Physiol. 2009 Sep;107(3):749-54. Epub 2009 Jul 16. | PUBMED |
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| Liu Y, Zhu L, Fatheree NY, Liu X, Pacheco SE, Tatevian N, Rhoads JM. Changes in intestinal Toll-like receptors and cytokines precede histological Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G442-50. Epub 2009 Jul | PUBMED |
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| Bodarky CL, Halene TB, Ehrlichman RS, Banerjee A, Ray R, Hahn CG, Jonak G, Siegel SJ. Novel environment and GABA agonists alter event-related potentials in J Pharmacol Exp Ther. 2009 Oct;331(1):308-18. Epub 2009 Jul 14. | PUBMED |
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| Jones OY, Lacson A, Zeng X, Jones JM, Katti K, Cahill RA, Ahmed AA. Long-term follow-up after non-myeloablative transplant of bone and marrow in BXSB Lupus. 2009 Aug;18(9):813-21. | PUBMED |
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| Zhu X, Wang M, Crump CH, Mishra A. An imbalance of esophageal effector and regulatory T cell subsets in experimental Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G550-8. Epub 2009 Jul 1. | PUBMED |
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| Helms MW, Kemming D, Contag CH, Pospisil H, Bartkowiak K, Wang A, Chang SY, Buerger H, Brandt BH. TOB1 is regulated by EGF-dependent HER2 and EGFR signaling, is highly Cancer Res. 2009 Jun 15;69(12):5049-56. Epub 2009 Jun 2. | PUBMED |
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| Pedroja BS, Kang LE, Imas AO, Carmeliet P, Bernstein AM. Plasminogen activator inhibitor-1 regulates integrin alphavbeta3 expression and J Biol Chem. 2009 Jul 31;284(31):20708-17. Epub 2009 Jun 1. | PUBMED |
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| Kumar P, Pandey KN. Cooperative activation of Npr1 gene transcription and expression by interaction Hypertension. 2009 Jul;54(1):172-8. Epub 2009 Jun 1. | PUBMED |
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| Ramamoorthy S, Donohue M, Buck M. Decreased Jun-D and myogenin expression in muscle wasting of human cachexia. Am J Physiol Endocrinol Metab. 2009 Aug;297(2):E392-401. Epub 2009 May 26. | PUBMED |
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| Merk M, Baugh J, Zierow S, Leng L, Pal U, Lee SJ, Ebert AD, Mizue Y, Trent JO, Mitchell R, Nickel W, Kavathas PB, Bernhagen J, Bucala R. The Golgi-associated protein p115 mediates the secretion of macrophage migration J Immunol. 2009 Jun 1;182(11):6896-906. | PUBMED |
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| Merk M, Baugh J, Zierow S, Leng L, Pal U, Lee SJ, Ebert AD, Mizue Y, Trent JO, Mitchell R, Nickel W, Kavathas PB, Bernhagen J, Bucala R. The Golgi-associated protein p115 mediates the secretion of macrophage migration J Immunol. 2009 Jun 1;182(11):6896-906. | PUBMED |
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| Bucks CM, Norton JA, Boesteanu AC, Mueller YM, Katsikis PD. Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion. J Immunol. 2009 Jun 1;182(11):6697-708. | PUBMED |
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| Bucks CM, Norton JA, Boesteanu AC, Mueller YM, Katsikis PD. Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion. J Immunol. 2009 Jun 1;182(11):6697-708. | PUBMED |
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| Doisne JM, Bartholin L, Yan KP, Garcia CN, Duarte N, Le Luduec JB, Vincent D, Cyprian F, Horvat B, Martel S, Rimokh R, Losson R, Benlagha K, Marie JC. iNKT cell development is orchestrated by different branches of TGF-beta J Exp Med. 2009 Jun 8;206(6):1365-78. Epub 2009 May 18. | PUBMED |
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| Sundstrom JB, Hair GA, Ansari AA, Secor WE, Gilfillan AM, Metcalfe DD, Kirshenbaum AS. IgE-FcepsilonRI interactions determine HIV coreceptor usage and susceptibility to J Immunol. 2009 May 15;182(10):6401-9. | PUBMED |
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| Matsushima H, Tanaka H, Mizumoto N, Takashima A. Identification of crassin acetate as a new immunosuppressant triggering heme Blood. 2009 Jul 2;114(1):64-73. Epub 2009 Apr 28. | PUBMED |
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| Vlotides G, Cooper O, Chen YH, Ren SG, Greenman Y, Melmed S. Heregulin regulates prolactinoma gene expression. Cancer Res. 2009 May 15;69(10):4209-16. Epub 2009 Apr 28. | PUBMED |
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| Mancinelli R, Onori P, Gaudio E, DeMorrow S, Franchitto A, Francis H, Glaser S, Carpino G, Venter J, Alvaro D, Kopriva S, White M, Kossie A, Savage J, Alpini G. Follicle-stimulating hormone increases cholangiocyte proliferation by an Am J Physiol Gastrointest Liver Physiol. 2009 Jul;297(1):G11-26. Epub 2009 Apr | PUBMED |
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| Rhoads RP, Johnson RM, Rathbone CR, Liu X, Temm-Grove C, Sheehan SM, Hoying JB, Allen RE. Satellite cell-mediated angiogenesis in vitro coincides with a functional Am J Physiol Cell Physiol. 2009 Jun;296(6):C1321-8. Epub 2009 Apr 22. | PUBMED |
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| Ben-Shachar S, Chahrour M, Thaller C, Shaw CA, Zoghbi HY. Mouse models of MeCP2 disorders share gene expression changes in the cerebellum Hum Mol Genet. 2009 Jul 1;18(13):2431-42. Epub 2009 Apr 15. | PUBMED |
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| Simanainen U, McNamara K, Gao YR, Handelsman DJ. Androgen sensitivity of prostate epithelium is enhanced by postnatal androgen Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1335-43. Epub 2009 Apr 14. | PUBMED |
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| Weaver KL, Ivester P, Seeds M, Case LD, Arm JP, Chilton FH. Effect of dietary fatty acids on inflammatory gene expression in healthy humans. J Biol Chem. 2009 Jun 5;284(23):15400-7. Epub 2009 Apr 9. | PUBMED |
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| Shen Z, Ajmo JM, Rogers CQ, Liang X, Le L, Murr MM, Peng Y, You M. Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-alpha Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1047-53. Epub 2009 Mar | PUBMED |
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| Kaposi-Novak P, Libbrecht L, Woo HG, Lee YH, Sears NC, Coulouarn C, Conner EA, Factor VM, Roskams T, Thorgeirsson SS. Central role of c-Myc during malignant conversion in human hepatocarcinogenesis. Cancer Res. 2009 Apr 1;69(7):2775-82. Epub 2009 Mar 10. | PUBMED |
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| Lobsiger CS, Boillee S, McAlonis-Downes M, Khan AM, Feltri ML, Yamanaka K, Cleveland DW. Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4465-70. Epub 2009 Feb 27. | PUBMED |
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| Xin H, Zhang C, Herrmann A, Du Y, Figlin R, Yu H. Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis Cancer Res. 2009 Mar 15;69(6):2506-13. Epub 2009 Feb 24. | PUBMED |
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| Maeda K, Malykhin A, Teague-Weber BN, Sun XH, Farris AD, Coggeshall KM. Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in Blood. 2009 May 7;113(19):4534-40. Epub 2009 Feb 17. | PUBMED |
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| Liao Y, Plummer NW, George MD, Abramowitz J, Zhu MX, Birnbaumer L. A role for Orai in TRPC-mediated Ca2+ entry suggests that a TRPC:Orai complex may Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3202-6. Epub 2009 Feb 12. | PUBMED |
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| Eid AA, Gorin Y, Fagg BM, Maalouf R, Barnes JL, Block K, Abboud HE. Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH Diabetes. 2009 May;58(5):1201-11. Epub 2009 Feb 10. | PUBMED |
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| Delibegovic M, Zimmer D, Kauffman C, Rak K, Hong EG, Cho YR, Kim JK, Kahn BB, Neel BG, Bence KK. Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves Diabetes. 2009 Mar;58(3):590-9. Epub 2008 Dec 15. | PUBMED |
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| Collins CE, La DT, Yang HT, Massin F,
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| Lu L, Li P, Yang C, Kurth T, Misale M,
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Choi YB, Nicholas J. Autocrine and paracrine promotion of
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Fleming AB, Pennings S. Tup1-Ssn6 and Swi-Snf remodelling
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Gregory-Evans CY, Moosajee M, Hodges MD, Mackay DS, Game
L, Vargesson N, Bloch-Zupan A, Rüschendorf F, Santos-Pinto L, Wackens
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Kim YS, Kang HS, Herbert R, Beak JY, Collins JB, Grissom
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Ma X, Shah Y, Cheung C, Guo GL, Feigenbaum L, Krausz KW,
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Ma X, Shah YM, Guo GL, Wang T, Krausz KW, Idle JR,
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Sama MA, Mathis DM, Furman JL, Mohmmad Abdul H, Artiushin
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Secchiero P, Corallini F, Rimondi E, Chiaruttini C, di
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Smed-S?ensen A, Moll M, Cheng TY, Lor?K, Norlin AC,
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Song Z, Deaciuc I, Zhou Z, Song M, Chen T, Hill D,
McClain CJ. Involvement of AMP-activated protein kinase in beneficial
effects of betaine on high-sucrose diet-induced hepatic steatosis. Am J
Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G894-902. Epub 2007
Aug 16. |
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Sung B, Pandey MK, Ahn KS, Yi T, Chaturvedi MM, Liu M,
Aggarwal BB Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of
histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated
gene products involved in cell survival, proliferation, invasion, and
inflammation through inhibition of the inhibitory subunit of nuclear
factor-kappaBalpha kinase, leading to potentiation of apoptosis Blood.
2008 May 15;111(10):4880-91. Epub 2008 Mar 18 |
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Wang T, Ma X, Krausz KW, Idle JR, Gonzalez FJ. Role of
pregnane X receptor in control of all-trans retinoic acid (ATRA)
metabolism and its potential contribution to ATRA resistance. J
Pharmacol Exp Ther. 2007 Oct 25; [Epub ahead of print] |
PUBMED |
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Weaver IC, D'Alessio AC, Brown SE, Hellstrom IC, Dymov S,
Sharma S, Szyf M, Meaney MJ. The transcription factor nerve growth
factor-inducible protein a mediates epigenetic programming: altering
epigenetic marks by immediate-early genes. J Neurosci. 2007 Feb
14;27(7):1756-68. |
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White DL, Saunders VA, Dang P, Engler J, Venables A, Zrim
S, Zannettino A, Lynch K, Manley PW, Hughes T. Most CML patients who
have a suboptimal response to imatinib have low OCT-1 activity: higher
doses of imatinib may overcome the negative impact of low OCT-1
activity. Blood. 2007 Dec 1;110(12):4064-72. Epub 2007 Aug 30 |
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| Rhee DY, Zhao XQ, Francis RJ, Huang GY, Mably JD, Lo CW. Connexin 43 regulates epicardial cell polarity and migration in coronary vascular Development. 2009 Sep;136(18):3185-93. | PUBMED |
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| Hanna M, Liu H, Amir J, Sun Y, Morris SW, Siddiqui MA, Lau LF, Chaqour B. Mechanical regulation of the proangiogenic factor CCN1/CYR61 gene requires the J Biol Chem. 2009 Aug 21;284(34):23125-36. Epub 2009 Jun 20. | PUBMED |
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| Collado MC, Donat E, Ribes-Koninckx C, Calabuig M, Sanz Y. Specific duodenal and faecal bacterial groups associated with paediatric coeliac J Clin Pathol. 2009 Mar;62(3):264-9. Epub 2008 Nov 7. | PUBMED |
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| Cheng J, Ma X, Krausz KW, Idle JR, Gonzalez FJ. Rifampicin-activated human pregnane X receptor and CYP3A4 induction enhance Drug Metab Dispos. 2009 Aug;37(8):1611-21. Epub 2009 May 21. | PUBMED |
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| Wahl C, Wegenka UM, Leithauser F, Schirmbeck R, Reimann J. IL-22-dependent attenuation of T cell-dependent (ConA) hepatitis in herpes virus J Immunol. 2009 Apr 15;182(8):4521-8. | PUBMED |
| Bio-Rad:
SYBR Green / Fluorescein |
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Chiao E, Elazar M, Xing Y, Xiong A, Kmet M, Millan MT,
Glenn JS, Wong WH, Baker J. Isolation and Transcriptional Profiling of
Purified Hepatic Cells Derived from Human Embryonic Stem Cells. Stem
Cells. 2008 Jun 5. [Epub ahead of print] |
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Han L, Lee DH, Szab?PE CTCF is the master organizer of
domain-wide allele-specific chromatin at the H19/Igf2 imprinted region.
Mol Cell Biol. 2008 Feb;28(3):1124-35. Epub 2007 Nov 26 |
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L? K, Culbertson M, Bradke F, Tessier-Lavigne M,
Tuszynski MH. Netrin-1 is a novel myelin-associated inhibitor to axon
growth. J Neurosci. 2008 Jan 30;28(5):1099-108 |
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Stark K, Wu ZL, Bartleson CJ, Guengerich FP. mRNA
Distribution and Heterologous Expression of Orphan Cytochrome P450 20A1.
Drug Metab Dispos. 2008 Jun 9. [Epub ahead of print] |
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Qin S, Liu T, Kamanna VS, Kashyap ML Pioglitazone
stimulates apolipoprotein A-I production without affecting HDL removal
in HepG2 cells: involvement of PPAR-alpha. Arterioscler Thromb Vasc
Biol. 2007 Nov;27(11):2428-34. Epub 2007 Sep 13. |
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| Menze MA, Boswell L, Toner M, Hand SC. Occurrence of mitochondria-targeted Late Embryogenesis Abundant (LEA) gene in J Biol Chem. 2009 Apr 17;284(16):10714-9. Epub 2009 Feb 19. | PUBMED |
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| Larman BW, Karolak MJ, Adams DC, Oxburgh L. Chordin-like 1 and twisted gastrulation 1 regulate BMP signaling following kidney J Am Soc Nephrol. 2009 May;20(5):1020-31. Epub 2009 Apr 8. | PUBMED |
| Others:
SYBR Green |
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Brown SE, Szyf M. Epigenetic programming of the rRNA
promoter by MBD3 Mol Cell Biol. 2007 Jul;27(13):4938-52. Epub 2007 Apr
23. |
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Carreras E, Turner S, Paharkova-Vatchkova V, Mao A,
Dascher C, Kovats S. Estradiol acts directly on bone marrow myeloid
progenitors to differentially regulate GM-CSF or Flt3 ligand-mediated
dendritic cell differentiation J Immunol. 2008 Jan
15;180(2):727-38. |
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Emmons J, Townley-Tilson WH, Deleault KM, Skinner SJ,
Gross RH, Whitfield ML, Brooks SA Identification of TTP mRNA targets in
human dendritic cells reveals TTP as a critical regulator of dendritic
cell maturation. RNA. 2008 May;14(5):888-902. Epub 2008 Mar 26. |
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Hernandez Y, Shpak M, Duarte TT, Mendez TL, Maldonado RA,
Roychowdhury S, Rodrigues ML, Das S. Novel role of sphingolipid
synthesis genes in regulating giardial encystation. Infect Immun. 2008
Jul;76(7):2939-49. Epub 2008 Apr 21. |
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Hu W, Mahavadi S, Li F, Murthy KS. Up-Regulation of RGS4
and Down-Regulation of CPI-17 Mediate Inhibition of Colonic Muscle
Contraction by Interleukin-1{beta} Am J Physiol Cell Physiol. 2007 Oct
24; [Epub ahead of print] |
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Kim JS, Bailey MJ, Ho AK, Møller M, Gaildrat P, Klein
DC. Daily rhythm in pineal phosphodiesterase (PDE) activity reflects
adrenergic/3',5'-cyclic adenosine 5'-monophosphate induction of the
PDE4B2 variant. Endocrinology. 2007 Apr;148(4):1475-85. Epub 2007 Jan 4. |
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Kopp JL, Ormsbee BD, Desler M, Rizzino A. Small Increases
in the Level of Sox2 Trigger the Differentiation of Mouse Embryonic Stem
Cells. Stem Cells. 2008 Jan 31 [Epub ahead of print] |
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Kopp JL, Wilder PJ, Desler M, Kinarsky L, Rizzino A.
Different domains of the transcription factor ELF3 are required in a
promoter-specific manner and multiple domains control its binding to
DNA. J Biol Chem. 2007 Feb 2;282(5):3027-41. Epub 2006 Dec 5. |
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Peyrou M, Hanna PE, Cribb AE. Cisplatin, gentamicin, and
p-aminophenol induce markers of endoplasmic reticulum stress in the rat
kidneys. Toxicol Sci. 2007 Sep;99(1):346-53. Epub 2007 Jun 12. |
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Robert R, Carlile GW, Pavel C, Liu N, Anjos SM, Liao J,
Luo Y, Zhang D, Thomas DY, Hanrahan JW. Structural analogue of
sildenafil identified as a novel corrector of the F508del-CFTR
trafficking defect. Mol Pharmacol. 2007 Nov 1; [Epub ahead of print |
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Seijffers R, Mills CD, Woolf CJ. ATF3 increases the
intrinsic growth state of DRG neurons to enhance peripheral nerve
regeneration. J Neurosci. 2007 Jul 25;27(30):7911-20. |
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Soundararajan R, Wishart AD, Rupasinghe HP,
Arcellana-Panlilio M, Nelson CM, Mayne M, Robertson GS.
Quercetin-3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro
against oxidative damage by inducing SREBP-2 mediated cholesterol
biosynthesis. J Biol Chem. 2007 Nov 20 [Epub ahead of print]. |
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Stepanova V, Lebedeva T, Kuo A, Yarovoi S, Tkachuk S,
Zaitsev S, Bdeir K, Dumler I, Marks MS, Parfyonova Y, Tkachuk VA, Higazi
AA, Cines DB. Nuclear translocation of urokinase-type plasminogen
activator. Blood. 2008 Jul 1;112(1):100-10. Epub 2008 Mar 12. |
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Wang T, Ma X, Krausz KW, Idle JR, Gonzalez FJ. Role of
pregnane X receptor in control of all-trans retinoic acid (ATRA)
metabolism and its potential contribution to ATRA resistance. J
Pharmacol Exp Ther. 2008 Feb;324(2):674-84. Epub 2007 Oct 25. |
PUBMED |
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Wu S, Peng J, Duncan MR, Kasisomayajula K, Grotendorst G,
Bancalari E ALK-5 Mediates Endogenous and TGF-{beta}1-induced Expression
of CTGF in Embryonic Lung. Am J Respir Cell Mol Biol. 2006 Dec 29; [Epub
ahead of print]. |
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Yan Y, Black CP, Cao PT, Haferbier JL, Kolb RH, Spieker
RS, Ristow AM, Cowan KH. Gamma-irradiation-induced DNA damage checkpoint
activation involves feedback regulation between extracellular
signal-regulated kinase 1/2 and BRCA1. Cancer Res. 2008 Jul
1;68(13):5113-21. |
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You M, Liang X, Ajmo JM, Ness GC Involvement of mammalian
sirtuin 1 in the action of ethanol in the liver. Am J Physiol
Gastrointest Liver Physiol. 2008 Apr;294(4):G892-8. Epub 2008 Jan
31 |
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Zhang MY, Wu X, Lee AJ, Jin W, Chang M, Wright A,
Imaizumi T, Sun SC. Regulation of I{kappa}B Kinase-related Kinases and
Antiviral Responses by Tumor Suppressor CYLD. J Biol Chem. 2008 Jul
4;283(27):18621-6. Epub 2008 May 8. |
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Zolfaghari R, Cifelli CJ, Lieu SO, Chen Q, Li NQ, Ross
AC. Lipopolysaccharide opposes the induction of CYP26A1 and CYP26B1 gene
expression by retinoic acid in the rat liver in vivo. Am J Physiol
Gastrointest Liver Physiol. 2007 Apr;292(4):G1029-36. Epub 2006 Dec 21 |
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| Liu D, Kebaier C, Pakpour N, Capul AA, Beverley SM, Scott P, Uzonna JE. Leishmania major phosphoglycans influence the host early immune response by Infect Immun. 2009 Aug;77(8):3272-83. Epub 2009 Jun 1. | PUBMED |
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| Ho LH, Taylor R, Dorstyn L, Cakouros D, Bouillet P, Kumar S. A tumor suppressor function for caspase-2. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5336-41. Epub 2009 Mar 11. | PUBMED |
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| Suh HC, Ji M, Gooya J, Lee M, Klarmann KD, Keller JR. Cell-nonautonomous function of Id1 in the hematopoietic progenitor cell niche. Blood. 2009 Aug 6;114(6):1186-95. Epub 2009 May 28. | PUBMED |
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| Cheng SM, Li JC, Lin SS, Lee DC, Liu L, Chen Z, Lau AS. HIV-1 transactivator protein induction of suppressor of cytokine signaling-2 Blood. 2009 May 21;113(21):5192-201. Epub 2009 Mar 11. | PUBMED |
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| Evans RT, Seasholtz AF. Soluble corticotropin-releasing hormone receptor 2alpha splice variant is Endocrinology. 2009 Sep;150(9):4191-202. Epub 2009 Jun 11. | PUBMED |
BACK TO TOP
Oligo GEArray DNA Microarrays
| Angiogenesis |
|
Lazar AJ, Das P, Tuvin D, Korchin B, Zhu Q, Jin Z,
Warneke CL, Zhang PS, Hernandez V, Lopez-Terrada D, Pisters PW, Pollock
RE, Lev D Angiogenesis-promoting gene patterns in alveolar soft part
sarcoma Clin Cancer Res. 2007 Dec 15;13(24):7314-21 |
PUBMED |
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Yi M, Schnitzer JE. Impaired tumor growth, metastasis,
angiogenesis and wound healing in annexin A1-null mice. Proc Natl Acad
Sci U S A. 2009 Oct 20;106(42):17886-91. Epub 2009 Oct 1. |
PUBMED |
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Gueron G, De Siervi A, Ferrando M, Salierno M, De Luca
P, Elguero B, Meiss R, Navone N, Vazquez ES. Critical role of endogenous
heme oxygenase 1 as a tuner of the invasive potential of prostate cancer
cells. Mol Cancer Res. 2009 Nov;7(11):1745-55. Epub 2009 Nov 10. |
PUBMED |
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| Apoptosis |
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Azuma T, Yao S, Zhu G, Flies AS, Flies SJ, Chen L. B7-H1
is a ubiquitous antiapoptotic receptor on cancer cells. Blood. 2008 Apr
1;111(7):3635-43. Epub 2008 Jan 25. |
PUBMED |
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Leng Y, Chuang DM. Endogenous alpha-synuclein
is induced by valproic acid through histone deacetylase inhibition and
participates in neuroprotection against glutamate-induced excitotoxicity.
J Neurosci. 2006 Jul 12;26(28):7502-12. |
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Low GK, Fok ED, Ting AP, Hande MP. Oxidative damage
induced genotoxic effects in human fibroblasts from Xeroderma
Pigmentosum group A patients. Int J Biochem Cell Biol. 2008 May 21. [Epub
ahead of print] |
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Nefedova Y, Sullivan DM, Bolick SC, Dalton WS,
Gabrilovich DI Inhibition of Notch signaling induces apoptosis of
myeloma cells and enhances sensitivity to chemotherapy. Blood. 2008 Feb
15;111(4):2220-9. Epub 2007 Nov 26. |
PUBMED |
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Pandey J, Umphress SM, Kang Y, Angdisen J, Naumova A,
Mercer KL, Jacks T, Jakowlew SB Modulation of tumor induction and
progression of oncogenic K-ras-positive tumors in the presence of TGF- 1
haploinsufficiency. Carcinogenesis. 2007 Dec;28(12):2589-96. Epub 2007
Aug 8 |
PUBMED |
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Staiger K, Staiger H, Weigert C, Haas C,
Haring HU, Kellerer M. Saturated, but not unsaturated, fatty acids
induce apoptosis of human coronary artery endothelial cells via nuclear
factor-kappaB activation. Diabetes. 2006 Nov;55(11):3121-6. |
PUBMED |
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Yan H, Frost P, Shi Y, Hoang B, Sharma S,
Fisher M, Gera J, Lichtenstein A. Mechanism by which mammalian target of
rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced
apoptosis Cancer Res. 2006 Feb 15;66(4):2305-13. |
PUBMED |
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Zhang M, Marshall B, Atherton SS. Murine cytomegalovirus
infection and apoptosis in organotypic retinal cultures Invest
Ophthalmol Vis Sci. 2008 Jan;49(1):295-303 |
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Zhou J, Liu M, Zhai Y, Xie W The Anti-Apoptotic Role of
Pregnane X Receptor in Human Colon Cancer Cells Mol Endocrinol. 2007 Dec
20 [Epub ahead of print] |
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Hu G, Barnes BJ. IRF-5 Is a Mediator of the Death Receptor-induced Apoptotic Signaling Pathway. J Biol Chem. 2009 Jan 30;284(5):2767-77. Epub 2008 Nov 20
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Li H, Ray G, Yoo BH, Erdogan M, Rosen KV. Down-regulation of Death-associated Protein Kinase-2 Is Required for {beta}-Catenin-induced Anoikis Resistance of Malignant Epithelial Cells. J Biol Chem. 2009 Jan 23;284(4):2012-22. Epub 2008 Oct 27
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Ottewell PD, M鰊kk鰊en H, Jones M, Lefley DV, Coleman RE, Holen I. Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer. J Natl Cancer Inst. 2008 Aug 20;100(16):1167-78.
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Wright CJ, Zhuang T, La P, Yang G, Dennery PA Hyperoxia-Induced NF-{kappa}B Activation Occurs Via A Maturationally Sensitive Atypical Pathway. Am J Physiol Lung Cell Mol Physiol. 2008 Dec 12. [Epub ahead of print]
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| Behl Y, Krothapalli P, Desta T, Roy S, Graves DT. FOXO1 plays an important role in enhanced microvascular cell apoptosis and Diabetes. 2009 Apr;58(4):917-25. Epub 2009 Jan 23. | PUBMED |
| | |
| Ottewell PD, Woodward JK, Lefley DV,
Evans CA, Coleman RE, Holen I. Anticancer mechanisms of doxorubicin and
zoledronic acid in breast cancer tumor growth in bone. Mol Cancer Ther.
2009 Oct;8(10):2821-32. Epub 2009 Sep 29. | PUBMED |
| Atherosclerosis |
|
Harvey EJ, Li N, Ramji DP. Critical role for
casein kinase 2 and phosphoinositide-3-kinase in the
interferon-gamma-induced expression of monocyte chemoattractant
protein-1 and other key genes implicated in atherosclerosis.
Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):806-12. Epub 2007 Jan 25 |
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Naiki Y, Sorrentino R, Wong MH, Michelsen KS, Shimada K, Chen S, Yilmaz A, Slepenkin A, Schr鰀er NW, Crother TR, Bulut Y, Doherty TM, Bradley M, Shaposhnik Z, Peterson EM, Tontonoz P, Shah PK, Arditi M TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis. J Immunol. 2008 Nov 15;181(10):7176-85
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| Breast
Cancer & Estrogen Receptor Signaling |
| Telang U, Brazeau DA, Morris ME. Comparison of the effects of phenethyl isothiocyanate and sulforaphane on gene Exp Biol Med (Maywood). 2009 Mar;234(3):287-95. Epub 2009 Jan 14. | PUBMED |
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Liu B, Ordonez-Ercan D, Fan Z, Huang X, Edgerton SM, Yang
X, Thor AD. Estrogenic promotion of ErbB2 tyrosine kinase activity in
mammary tumor cells requires activation of ErbB3 signaling. Mol Cancer
Res. 2009 Nov;7(11):1882-92. Epub 2009 Oct 27. |
PUBMED |
| Cancer |
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Bryan BA, Dyson OF, Akula SM. Identifying
cellular genes crucial for the reactivation of Kaposi's
sarcoma-associated herpesvirus latency. J Gen Virol. 2006 Mar;87(Pt
3):519-29. |
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Frommer KW, Reichenmiller K, Schutt BS,
Hoeflich A, Ranke MB, Dodt G, Elmlinger MW. IGF-independent effects of
IGFBP-2 on the human breast cancer cell line Hs578T. J Mol Endocrinol.
2006 Aug;37(1):13-23. |
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| Cancer
PathwayFinder |
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Li H, Fan X, Kovi RC, Jo Y, Moquin B, Konz R,
Stoicov C, Kurt-Jones E, Grossman SR, Lyle S, Rogers AB, Montrose M,
Houghton J. Spontaneous expression of embryonic factors and p53 point
mutations in aged mesenchymal stem cells: a model of age-related
tumorigenesis in mice. Cancer Res. 2007 Nov 15;67(22):10889-98. |
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Shao J, Washington MK, Saxena R, Sheng H Heterozygous
disruption of the PTEN promotes intestinal neoplasia in APCmin/+ mouse:
roles of osteopontin. Carcinogenesis. 2007 Dec;28(12):2476-83. Epub 2007
Aug 11 |
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| Cell
Cycle |
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Jang SI, Lee EJ, Hart PS, Ramaswami M, Pallos
D, Hart TC Germ line gain of function with SOS1 mutation in hereditary
gingival fibromatosis. J Biol Chem. 2007 Jul 13;282(28):20245-55. Epub
2007 May 17. |
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Klokk TI, Kilander A, Xi Z, Waehre H, Risberg
B, Danielsen HE, Saatcioglu F. Kallikrein 4 is a proliferative factor
that is overexpressed in prostate cancer. Cancer Res. 2007 Jun
1;67(11):5221-30 |
PUBMED |
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Pandey J, Umphress SM, Kang Y, Angdisen J, Naumova A,
Mercer KL, Jacks T, Jakowlew SB Modulation of tumor induction and
progression of oncogenic K-ras-positive tumors in the presence of TGF- 1
haploinsufficiency. Carcinogenesis. 2007 Dec;28(12):2589-96. Epub 2007
Aug 8 |
PUBMED |
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Rubinek T, Chesnokova V, Wolf I, Wawrowsky K,
Vlotides G, Melmed S Discordant proliferation and differentiation in
pituitary tumor-transforming gene-null bone marrow stem cells. Am J
Physiol Cell Physiol. 2007 Sep;293(3):C1082-92. Epub 2007 Jul 11 |
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| Lu J, Verma SC, Murakami M, Cai Q, Kumar P, Xiao B, Robertson ES. Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus J Virol. 2009 Jul;83(14):7129-41. Epub 2009 May 13. | PUBMED |
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| Liu L, Wang J, Zhao L, Nilsen J, McClure K, Wong K, Brinton RD. Progesterone increases rat neural progenitor cell cycle gene expression and Endocrinology. 2009 Jul;150(7):3186-96. Epub 2009 Apr 9. | PUBMED |
| | |
| Ottewell PD, Woodward JK, Lefley DV, Evans
CA, Coleman RE, Holen I. Anticancer mechanisms of doxorubicin and
zoledronic acid in breast cancer tumor growth in bone. Mol Cancer Ther.
2009 Oct;8(10):2821-32. Epub 2009 Sep 29. | PUBMED |
| Cell
Surface Markers |
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Wang L, O'Leary H, Fortney J, Gibson LF. Ph+/VE-cadherin+
identifies a stem cell like population of acute lymphoblastic leukemia
sustained by bone marrow niche cells. Blood. 2007 Nov 1;110(9):3334-44.
Epub 2007 Jul 16. |
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| Chemokines
& Receptors |
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Fischer J, West J, Agochukwu N, Suire C,
Hale-Donze H. Induction of host chemotactic response by Encephalitozoon
spp Infect Immun. 2007 Apr;75(4):1619-25. Epub 2006 Dec 18. |
PUBMED |
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Schenk S, Mal N, Finan A, Zhang M, Kiedrowski
M, Popovic Z, McCarthy PM, Penn MS. Monocyte chemotactic protein-3 is a
myocardial mesenchymal stem cell homing factor. Stem Cells. 2007
Jan;25(1):245-51. Epub 2006 Oct 19. |
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Sinha I, Cho BS, Roelofs KJ, Stanley JC,
Henke PK, Upchurch GR Jr Female gender attenuates cytokine and chemokine
expression and leukocyte recruitment in experimental rodent abdominal
aortic aneurysms. Ann N Y Acad Sci. 2006 Nov;1085:367-79 |
PUBMED |
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Son DS, Roby KF. Interleukin-1alpha-induced
chemokines in mouse granulosa cells: impact on keratinocyte
chemoattractant chemokine, a CXC subfamily. Mol Endocrinol. 2006
Nov;20(11):2999-3013. Epub 2006 Jul 6. |
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Weiss ML, Anderson C, Medicetty S, Seshareddy KB, Weiss RJ, Vanderwerff I, Troyer D, McIntosh KR. Immune Properties of Human Umbilical Cord Wharton's Jelly-Derived Cells. Stem Cells. 2008 Aug 14. [Epub ahead of print]
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Cagigi A, Mowafi F, Phuong Dang LV, Tenner-Racz K, Atlas A, Grutzmeier S, Racz P, Chiodi F, Nilsson A. Altered expression of the receptor-ligand pair CXCR5/CXCL13 in B cells during chronic HIV-1 infection. Blood. 2008 Dec 1;112(12):4401-10. Epub 2008 Sep 9.
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Yasuoka H, Yamaguchi Y, Feghali-Bostwick CA The Pro-fibrotic Factor IGFBP-5 Induces Lung Fibroblast and Mononuclear Cell Migration. Am J Respir Cell Mol Biol. 2009 Jan 8. [Epub ahead of print]
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| Common
Cytokines |
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Korshunov VA, Nikonenko TA, Tkachuk VA,
Brooks A, Berk BC Interleukin-18 and macrophage migration inhibitory
factor are associated with increased carotid intima-media thickening
Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):295-300. Epub 2005 Nov 17 |
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Lee JK, Mathew SO, Vaidya SV, Kumaresan PR,
Mathew PA. CS1 (CRACC, CD319) induces proliferation and autocrine
cytokine expression on human B lymphocytes. J Immunol. 2007 Oct
1;179(7):4672-8. |
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Ou R, Zhang M, Huang L, Flavell RA, Koni PA, Moskophidis
D. Regulation of immune response and inflammatory reactions against
viral infection by VCAM-1. J Virol. 2008 Mar;82(6):2952-65. Epub 2008
Jan 23 |
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Sinha I, Cho BS, Roelofs KJ, Stanley JC,
Henke PK, Upchurch GR Jr Female gender attenuates cytokine and chemokine
expression and leukocyte recruitment in experimental rodent abdominal
aortic aneurysms. Ann N Y Acad Sci. 2006 Nov;1085:367-79 |
PUBMED |
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| Coffelt SB, Tomchuck SL, Zwezdaryk KJ, Danka ES, Scandurro AB. Leucine leucine-37 uses formyl peptide receptor-like 1 to activate signal Mol Cancer Res. 2009 Jun;7(6):907-15. Epub 2009 Jun 2. | PUBMED |
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| Li C, Houser BL, Nicotra ML, Strominger JL. HLA-G homodimer-induced cytokine secretion through HLA-G receptors on human Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5767-72. Epub 2009 Mar 20. | PUBMED |
| | |
| Gupta S, Maitra R, Young D, Gupta A, Sen S. Silencing the myotrophin gene by RNA interference leads to the regression of Am J Physiol Heart Circ Physiol. 2009 Aug;297(2):H627-36. Epub 2009 Jun 5. | PUBMED |
| | |
| Jerde TJ, Bushman W. IL-1 induces IGF-dependent
epithelial proliferation in prostate development and reactive hyperplasia.
Sci Signal. 2009 Sep 1;2(86):ra49. | PUBMED |
| | |
| Jerde TJ, Bushman W. IL-1 induces IGF-dependent
epithelial proliferation in prostate development and reactive hyperplasia.
Sci Signal. 2009 Sep 1;2(86):ra49. | |
| Custom |
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Djamali A. Oxidative stress as a common
pathway to chronic tubulointerstitial injury in kidney allografts. Am J
Physiol Renal Physiol. 2007 Aug;293(2):F445-55. Epub 2007 Apr 25. |
PUBMED |
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Huang HS, Matevossian A, Whittle C, Kim SY,
Schumacher A, Baker SP, Akbarian S Prefrontal dysfunction in
schizophrenia involves mixed-lineage leukemia 1-regulated histone
methylation at GABAergic gene promoters. J Neurosci. 2007 Oct
17;27(42):11254-62. |
PUBMED |
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Kushnir AS, Davido DJ, Schaffer PA. Role of nuclear
factor Y in stress-induced activation of the herpes simplex virus type 1
ICP0 promoter. J Virol. 2010 Jan;84(1):188-200. |
PUBMED |
| Dendritic
& Antigen Presenting Cells |
|
Luo Y, Schwartz C, Shin S, Zeng X, Chen N,
Wang Y, Yu X, Rao MS. A focused microarray to assess dopaminergic and
glial cell differentiation from fetal tissue or embryonic stem cells
Stem Cells. 2006 Apr;24(4):865-75. Epub 2005 Dec 15. |
PUBMED |
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| Li X, Yang A, Huang H, Zhang X, Town J, Davis B, Cockcroft DW, Gordon JR. Induction of Th2 Cell Allergen Tolerance by IL-10-differentiated Regulatory Am J Respir Cell Mol Biol. 2009 Apr 16. | PUBMED |
| DNA
Damage Signaling |
|
Chesnokova V, Zonis S, Rubinek T, Yu R, Ben-Shlomo
A, Kovacs K, Wawrowsky K, Melmed S. Senescence mediates pituitary
hypoplasia and restrains pituitary tumor growth. Cancer Res. 2007 Nov
1;67(21):10564-72. |
PUBMED |
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Chesnokova V, Wong C, Zonis S, Gruszka A, Wawrowsky K, Ren SG, Benshlomo A, Yu R. Diminished pancreatic {beta} cell mass in securin-null mice is caused by {beta} cell apoptosis and senescence. Endocrinology. 2009 Feb 12. [Epub ahead of print]
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PUBMED |
| Extracellular
Matrix & Adhesion Molecules |
|
Hannan NJ, Salamonsen LA. CX3CL1 and CCL14 Regulate
Extracellular Matrix and Adhesion Molecules in the Trophoblast:
Potential Roles in Human Embryo Implantation. Biol Reprod. 2008
Jul;79(1):58-65. Epub 2008 Mar 26. |
PUBMED |
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Khan ZA, Melero-Martin JM, Wu X, Paruchuri S, Boscolo E,
Mulliken JB, Bischoff J. Endothelial progenitor cells from infantile
hemangioma and umbilical cord blood display unique cellular responses to
endostatin. Blood. 2006 Aug 1;108(3):915-21. |
PUBMED |
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Romain D, Sylvie BP, Johanna L, Alain M, Aurelie D,
Fran?is-Xavier M, William H, Irfan R, Frank A. Laboratoire de
Biochimie, Universit?de REIMS Champagne-Ardenne, CNRS UMR-6237, 51095
REIMS Cedex, France Biochim Biophys Acta. 2008 Jun 13. [Epub ahead of
print] |
PUBMED |
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Taniwaki K, Fukamachi H, Komori K, Ohtake Y, Nonaka T,
Sakamoto T, Shiomi T, Okada Y, Itoh T, Itohara S, Seiki M, Yana I.
Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type
1-MMP-dependent tumor growth in mice. Cancer Res. 2007 May
1;67(9):4311-9 |
PUBMED |
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Sung SY, Hsieh CL, Law A, Zhau HE, Pathak S, Multani AS, Lim S, Coleman IM, Wu LC, Figg WD, Dahut WL, Nelson P, Lee JK, Amin MB, Lyles R, Johnstone PA, Marshall FF, Chung LW. Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis. Cancer Res. 2008 Dec 1;68(23):9996-10003
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PUBMED |
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Bin Hafeez B, Adhami VM, Asim M, Siddiqui IA, Bhat KM, Zhong W, Saleem M, Din M, Setaluri V, Mukhtar H. Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator. Clin Cancer Res. 2009 Jan 15;15(2):452-9.
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PUBMED |
| Hypoxia
Signaling |
|
Kubo M, Li TS, Suzuki R, Shirasawa B, Morikage N, Ohshima
M, Qin SL, Hamano K Hypoxic preconditioning increases survival and
angiogenic potency of peripheral blood mononuclear cells via oxidative
stress resistance Am J Physiol Heart Circ Physiol. 2008
Feb;294(2):H590-5. Epub 2007 Dec 21 |
PUBMED |
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| Hematopoesis |
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Laricchia-Robbio L, Premanand K, Rinaldi CR, Nucifora G. EVI1 Impairs Myelopoiesis by Deregulation of PU.1 Function. Cancer Res. 2009 Feb 10. [Epub ahead of print]
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PUBMED |
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| Inflammatory
Cytokines & Receptors |
|
Aravalli RN, Hu S, Rowen TN, Palmquist JM,
Lokensgard JR. Cutting edge: TLR2-mediated proinflammatory cytokine and
chemokine production by microglial cells in response to herpes simplex
virus J Immunol. 2005 Oct 1;175(7):4189-93. |
PUBMED |
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Ganta CK, Helwig BG, Blecha F, Ganta RR,
Cober R, Parimi S, Musch TI, Fels RJ, Kenney MJ.
"Hypothermia-enhanced Splenic Cytokine Gene Expression is
Independent of the Sympathetic Nervous System. Am J Physiol Regul Integr
Comp Physiol. 2006 Feb 9; [Epub ahead of print] |
PUBMED |
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Lee JH, Kim M, Im YS, Choi W, Byeon SH, Lee HK NFAT5
induction and its role in hyperosmolar stressed human limbal epithelial
cells. Invest Ophthalmol Vis Sci. 2008 May;49(5):1827-35 |
PUBMED |
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Rupprecht TA, Angele B, Klein M, Heesemann J,
Pfister HW, Botto M, Koedel U. Complement C1q and C3 are critical for
the innate immune response to Streptococcus pneumoniae in the central
nervous system. J Immunol. 2007 Feb 1;178(3):1861-9. |
PUBMED |
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Vera PL, Wang X, Meyer-Siegler KL. Upregulation of
macrophage migration inhibitory factor (MIF) and CD74, receptor for MIF,
in rat bladder during persistent cyclophosphamide-induced inflammation
Exp Biol Med (Maywood). 2008 May;233(5):620-6. Epub 2008 Mar 28. |
PUBMED |
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Nacu N, Luzina IG, Highsmith K, Lockatell V, Pochetuhen
K, Cooper ZA, Gillmeister MP, Todd NW, Atamas SP Macrophages produce TGF-beta-induced
(beta-ig-h3) following ingestion of apoptotic cells and regulate MMP14
levels and collagen turnover in fibroblasts J Immunol. 2008 Apr
1;180(7):5036-44 |
PUBMED |
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Bald? A, Gomes AV, Ping P, Edwards PA. Loss of ABCG1
Results in Chronic Pulmonary Inflammation. J Immunol. 2008 Mar
1;180(5):3560-8 |
PUBMED |
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Tran TA, McCoy MK, Sporn MB, Tansey MG. The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection. J Neuroinflammation. 2008 May 12;5:14.
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PUBMED |
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| Buvanendran A, Mitchell K, Kroin JS, Iadarola MJ. Cytokine gene expression after total hip arthroplasty: surgical site versus Anesth Analg. 2009 Sep;109(3):959-64. | PUBMED |
| | |
| Inflammatory Response and Autoimmunity |
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Vyas K, Chaudhuri S, Leaman DW, Komar AA, Musiyenko A, Barik S, Mazumder B. Genome-wide polysome profiling reveals an inflammation-responsive posttranscriptional operon in gamma interferon-activated monocytes. Mol Cell Biol. 2009 Jan;29(2):458-70. Epub 2008 Nov 10
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PUBMED |
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Li Z, Liu B, Maminishkis A, Mahesh SP, Yeh S, Lew J, Lim WK, Sen HN, Clarke G, Buggage R, Miller SS, Nussenblatt RB. Gene expression profiling in autoimmune noninfectious uveitis disease. J Immunol. 2008 Oct 1;181(7):5147-57.
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PUBMED |
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Abolhassani M, Aloulou N, Chaumette MT, Aparicio T, Martin-Garcia N, Mansour H, Le Gouvello S, Delchier JC, Sobhani I. Leptin receptor-related immune response in colorectal tumors: the role of colonocytes and interleukin-8. Cancer Res. 2008 Nov 15;68(22):9423-32
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PUBMED |
| Insulin
Signaling |
|
Fulzele K, DiGirolamo DJ, Liu Z, Xu J,
Messina JL, Clemens TL. Disruption of the insulin-like growth factor
type 1 receptor in osteoblasts enhances insulin signaling and action. J
Biol Chem. 2007 Aug 31;282(35):25649-58. Epub 2007 Jun 6. |
PUBMED |
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Vyas K, Chaudhuri S, Leaman DW, Komar AA, Musiyenko A, Barik S, Mazumder B. Genome-wide polysome profiling reveals an inflammation-responsive posttranscriptional operon in gamma interferon-activated monocytes. Mol Cell Biol. 2009 Jan;29(2):458-70. Epub 2008 Nov 10
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PUBMED |
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| Lennon R, Pons D, Sabin MA, Wei C, Shield JP, Coward RJ, Tavare JM, Mathieson PW, Saleem MA, Welsh GI. Saturated fatty acids induce insulin resistance in human podocytes: implications Nephrol Dial Transplant. 2009 Nov;24(11):3288-96. Epub 2009 Jun 25. | PUBMED |
| JAK
/ STAT Signaling |
|
Liby K, Voong N, Williams CR, Risingsong R,
Royce DB, Honda T, Gribble GW, Sporn MB, Letterio JJ. The synthetic
triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and
induces apoptosis in myeloma and lung cancer cells. Clin Cancer Res.
2006 Jul 15;12(14 Pt 1):4288-93. |
PUBMED |
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Vargas-Inchaustegui DA, Xin L, Soong L Leishmania
braziliensis Infection Induces Dendritic Cell Activation, ISG15
Transcription, and the Generation of Protective Immune Responses. J
Immunol. 2008 Jun 1;180(11):7537-45. |
PUBMED |
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| Torroella-Kouri M, Silvera R, Rodriguez D, Caso R, Shatry A, Opiela S, Ilkovitch D, Schwendener RA, Iragavarapu-Charyulu V, Cardentey Y, Strbo N, Lopez DM. Identification of a subpopulation of macrophages in mammary tumor-bearing mice Cancer Res. 2009 Jun 1;69(11):4800-9. Epub 2009 May 19. | PUBMED |
| Neurogenesis
& Neural Stem Cells |
|
Greco SJ, Rameshwar P Enhancing effect of
IL-1alpha on neurogenesis from adult human mesenchymal stem cells:
implication for inflammatory mediators in regenerative medicine. J
Immunol. 2007 Sep 1;179(5):3342-50 |
PUBMED |
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| NFκB Signaling |
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de Oliveira-Marques V, Cyrne L, Marinho HS,
Antunes F A Quantitative Study of NF-{kappa}B Activation by H2O2:
Relevance in Inflammation and Synergy with TNF-{alpha}. J Immunol. 2007
Mar 15;178(6):3893-902. |
PUBMED |
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Emdad L, Sarkar D, Su ZZ, Randolph A,
Boukerche H, Valerie K, Fisher PB Activation of the nuclear factor
kappaB pathway by astrocyte elevated gene-1: implications for tumor
progression and metastasis Cancer Res. 2006 Feb 1;66(3):1509-16. |
PUBMED |
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Liu B, Li Z, Mahesh SP, Pantanelli S, Hwang FS, Siu WO,
Nussenblatt RB. Glucocorticoid-induced Tumor Necrosis Factor Receptor
Negatively Regulates Activation of Human Primary Natural Killer (NK)
Cells by Blocking Proliferative Signals and Increasing NK Cell
Apoptosis. J Biol Chem. 2008 Mar 28;283(13):8202-10. Epub 2008 Jan
29 |
PUBMED |
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Catalano A, Lazzarini R, Di Nuzzo S, Orciari S, Procopio A. The Plexin-A1 Receptor Activates Vascular Endothelial Growth Factor-Receptor 2 and Nuclear Factor-{kappa}B to Mediate Survival and Anchorage-Independent Growth of Malignant Mesothelioma Cells. Cancer Res. 2009 Jan 27. [Epub ahead of print]
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PUBMED |
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| Farhana L, Dawson MI, Xu L, Fontana JA. SHP and Sin3A expression are essential for adamantyl-substituted retinoid-related Mol Cancer Ther. 2009 Jun;8(6):1625-35. Epub 2009 Jun 9. | PUBMED |
| Notch
Signaling |
|
Wang L, O'Leary H, Fortney J, Gibson LF. Ph+/VE-cadherin+
identifies a stem cell like population of acute lymphoblastic leukemia
sustained by bone marrow niche cells. Blood. 2007 Nov 1;110(9):3334-44.
Epub 2007 Jul 16. |
PUBMED |
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| Singh M, Mukherjee P, Narayanasamy K, Arora R, Sen SD, Gupta S, Natarajan K, Malhotra P. Proteome analysis of Plasmodium falciparum extracellular secretory antigens at Mol Cell Proteomics. 2009 Sep;8(9):2102-18. Epub 2009 Jun 3. | PUBMED |
| Osteogenesis |
|
Surmann-Schmitt C, Dietz U, Kireva T, Adam N, Park J,
Tagariello A, Onnerfjord P, Heineg?d D, Schl?zer-Schrehardt U,
Deutzmann R, von der Mark K, Stock M. Ucma, a Novel Secreted
Cartilage-specific Protein with Implications in Osteogenesis J Biol
Chem. 2008 Mar 14;283(11):7082-93. Epub 2007 Dec 21 |
PUBMED |
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Galdones E, Hales BF. Retinoic acid receptor gamma-induced misregulation of chondrogenesis in the murine limb bud in vitro. Toxicol Sci. 2008 Nov;106(1):223-32. Epub 2008 Aug 14
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PUBMED |
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| p53
Signaling Pathway |
| Ishii H, Du H, Zhang Z, Henderson A, Sen R, Pazin MJ. Mi2beta shows chromatin enzyme specificity by erasing a DNase I-hypersensitive J Biol Chem. 2009 Mar 20;284(12):7533-41. Epub 2009 Jan 21. | PUBMED |
| Prostate Cancer |
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Bianchini A, Loiarro M, Bielli P, Bus?R, Paronetto MP, Loreni F, Geremia R, Sette C Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells. Carcinogenesis. 2008 Dec;29(12):2279-88. Epub 2008 Sep 22
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PUBMED |
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| Signal
Transductioin in Cancer |
| Zeng H, Wu M, Botnen JH. Methylselenol, a selenium metabolite, induces cell cycle arrest in G1 phase and J Nutr. 2009 Sep;139(9):1613-8. Epub 2009 Jul 22. | PUBMED |
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| Signal
Transduction PathwayFinder |
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Kapoor R, Sheng JJ. Transfection of human
prostate cancer CA-HPV-10 cells with cytosolic sulfotransferase SULT1E1
affects estrogen signaling and gene transcription. Drug Metab Dispos.
2007 Nov 5; [Epub ahead of print] |
PUBMED |
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Mirotsou M, Zhang Z, Deb A, Zhang L, Gnecchi
M, Noiseux N, Mu H, Pachori A, Dzau V. Secreted frizzled related protein
2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor
mediating myocardial survival and repair. Proc Natl Acad Sci U S A. 2007
Jan 30;104(5):1643-8. Epub 2007 Jan 24. |
PUBMED |
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| Shamhart PE, Luther DJ, Hodson BR, Koshy JC, Ohanyan V, Meszaros JG. Impact of type 1 diabetes on cardiac fibroblast activation: enhanced cell cycle Am J Physiol Endocrinol Metab. 2009 Aug 25. | PUBMED |
| | |
| Liu XS, Chopp M, Zhang RL, Hozeska-Solgot A, Gregg SC, Buller B, Lu M, Zhang ZG. Angiopoietin 2 mediates the differentiation and migration of neural progenitor J Biol Chem. 2009 Aug 21;284(34):22680-9. Epub 2009 Jun 24. | PUBMED |
| Stem
Cell |
|
Wang L, O'Leary H, Fortney J, Gibson LF. Ph+/VE-cadherin+
identifies a stem cell like population of acute lymphoblastic leukemia
sustained by bone marrow niche cells. Blood. 2007 Nov 1;110(9):3334-44.
Epub 2007 Jul 16. |
PUBMED |
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| TGFβ / BMP Signaling |
|
Kato M, Zhang J, Wang M, Lanting L, Yuan H,
Rossi JJ, Natarajan R. MicroRNA-192 in diabetic kidney glomeruli and its
function in TGF-beta-induced collagen expression via inhibition of E-box
repressors. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3432-7. Epub
2007 Feb 20. |
PUBMED |
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Yamashita M, Otsuka F, Mukai T, Otani H, Inagaki K,
Miyoshi T, Goto J, Yamamura M, Makino H Simvastatin antagonizes tumor
necrosis factor-alpha inhibition of bone morphogenetic
proteins-2-induced osteoblast differentiation by regulating Smad
signaling and Ras/Rho-mitogen-activated protein kinase pathway. J
Endocrinol. 2008 Mar;196(3):601-13 |
PUBMED |
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Takahashi M, Otsuka F, Miyoshi T, Otani H, Goto J, Yamashita M, Ogura T, Makino H, Doihara H. Bone morphogenetic protein 6 (BMP6) and BMP7 inhibit estrogen-induced proliferation of breast cancer cells by suppressing p38 mitogen-activated protein kinase activation. J Endocrinol. 2008 Dec;199(3):445-55. Epub 2008 Sep 9.
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PUBMED |
| Th1 / Th2 |
|
Lee JK, McCoy MK, Harms AS, Ruhn KA, Gold SJ, Tansey MG. Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response. J Neurosci. 2008 Aug 20;28(34):8517-28.
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PUBMED |
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| Toll-Like
Receptor Signaling Pathway |
| Sharma A, Maheshwari RK. Oligonucleotide array analysis of Toll-like receptors and associated signalling J Gen Virol. 2009 Aug;90(Pt 8):1836-47. Epub 2009 Apr 15. | PUBMED |
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| Toxicology
& Drug Resistance |
|
Zhang L, Hannay JA, Liu J, Das P, Zhan M,
Nguyen T, Hicklin DJ, Yu D, Pollock RE, Lev D. Vascular endothelial
growth factor overexpression by soft tissue sarcoma cells: implications
for tumor growth, metastasis, and chemoresistance. Cancer Res. 2006 Sep
1;66(17):8770-8. |
PUBMED |
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L鰊n-Stensrud J, Landin MA, Benneche T, Petersen FC, Scheie AA Furanones, potential agents for preventing Staphylococcus epidermidis biofilm infections? J Antimicrob Chemother. 2009 Feb;63(2):309-16. Epub 2008 Dec 20
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PUBMED |
| Tumor
Metastasis |
|
Li H, Fan X, Kovi RC, Jo Y, Moquin B, Konz R,
Stoicov C, Kurt-Jones E, Grossman SR, Lyle S, Rogers AB, Montrose M,
Houghton J. Spontaneous expression of embryonic factors and p53 point
mutations in aged mesenchymal stem cells: a model of age-related
tumorigenesis in mice. Cancer Res. 2007 Nov 15;67(22):10889-98. |
PUBMED |
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| Satpathy M, Shao M, Emerson R, Donner DB, Matei D. Tissue transglutaminase regulates matrix metalloproteinase-2 in ovarian cancer by J Biol Chem. 2009 Jun 5;284(23):15390-9. Epub 2009 Mar 26. | PUBMED |
| WNT
Signaling |
|
Baksh D, Yao R, Tuan RS. Comparison of
proliferative and multilineage differentiation potential of human
mesenchymal stem cells derived from umbilical cord and bone marrow. Stem
Cells. 2007 Jun;25(6):1384-92. Epub 2007 Mar 1. |
PUBMED |
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Giuliani N, Morandi F, Tagliaferri S,
Lazzaretti M, Donofrio G, Bonomini S, Sala R, Mangoni M, Rizzoli V.
Production of Wnt inhibitors by myeloma cells: potential effects on
canonical Wnt pathway in the bone microenvironment. Cancer Res. 2007 Aug
15;67(16):7665-74 |
PUBMED |
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Liu Z, Habener JF. Glucagon-like Peptide-1 Activation of
TCF7L2-dependent Wnt Signaling Enhances Pancreatic Beta Cell
Proliferation. J Biol Chem. 2008 Mar 28;283(13):8723-35. Epub 2008 Jan
23 |
PUBMED |
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Ortega P, Mor? A, de Juan C, Fr?s C, Hern?dez S,
L?ez-Asenjo JA, S?chez-Pernaute A, Torres A, Iniesta P, Benito M.
Differential Wnt pathway gene expression and E-cadherin truncation in
sporadic colorectal cancers with and without microsatellite instability.
Clin Cancer Res. 2008 Feb 15;14(4):995-1001 |
PUBMED |
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Wang L, O'Leary H, Fortney J, Gibson LF. Ph+/VE-cadherin+
identifies a stem cell like population of acute lymphoblastic leukemia
sustained by bone marrow niche cells. Blood. 2007 Nov 1;110(9):3334-44.
Epub 2007 Jul 16 |
PUBMED |
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Groen RW, Oud ME, Schilder-Tol EJ, Overdijk MB, ten Berge D, Nusse R, Spaargaren M, Pals ST. Illegitimate WNT pathway activation by beta-catenin mutation or autocrine stimulation in T-cell malignancies. Cancer Res. 2008 Sep 1;68(17):6969-77.
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PUBMED |
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Shah GV, Muralidharan A, Gokulgandhi M, Soan K, Thomas S. Cadherin switching and activation of beta-catenin signaling underlie proinvasive actions of calcitonin-calcitonin receptor axis in prostate cancer. J Biol Chem. 2009 Jan 9;284(2):1018-30. Epub 2008 Nov 9.
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PUBMED |
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BACK TO TOP
CASE Kits
| AKT |
|
Cantiani L, Manara MC, Zucchini C, De Sanctis
P, Zuntini M, Valvassori L, Serra M, Olivero M, Di Renzo MF, Colombo MP,
Picci P, Scotlandi K. Caveolin-1 reduces osteosarcoma metastases by
inhibiting c-Src activity and met signaling. Cancer Res. 2007 Aug
15;67(16):7675-85. |
PUBMED |
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Choudhari SR, Khan MA, Harris G, Picker D,
Jacob GS, Block T, Shailubhai K. Deactivation of Akt and STAT3 signaling
promotes apoptosis, inhibits proliferation, and enhances the sensitivity
of hepatocellular carcinoma cells to an anticancer agent, Atiprimod. Mol
Cancer Ther. 2007 Jan;6(1):112-21. |
PUBMED |
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Koshkin V, Dai FF, Robson-Doucette CA, Chan CB, Wheeler
MB Limited Mitochondrial Permeabilization Is an Early Manifestation of
Palmitate-induced Lipotoxicity in Pancreatic {beta}-Cells J Biol Chem.
2008 Mar 21;283(12):7936-48. Epub 2007 Dec 26 |
PUBMED |
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Singla DK, Singla RD, McDonald DE. Factors Released
from Embryonic Stem Cells inhibit Apoptosis in H9c2 cells through
P1-3kinase/Akt but not ERK pathway. Am J Physiol Heart Circ Physiol.
2008 Jun 13. [Epub ahead of print] |
PUBMED |
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Xia S, Forman LW, Faller DV. Protein kinase C
delta is required for survival of cells expressing activated p21RAS. J
Biol Chem. 2007 May 4;282(18):13199-210. Epub 2007 Mar 8. |
PUBMED |
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Kurtagic E, Jedrychowski MP, Nugent MA. Neutrophil Elastase Cleaves VEGF to Generate a VEGF Fragment with Altered Activity. Am J Physiol Lung Cell Mol Physiol. 2009 Jan 9. [Epub ahead of print]
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PUBMED |
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| ERBB2 |
|
Park JM, Terabe M, Steel JC, Forni G, Sakai Y, Morris
JC, Berzofsky JA. Therapy of advanced established murine breast cancer
with a recombinant adenoviral ErbB-2/neu vaccine Cancer Res. 2008 Mar
15;68(6):1979-87 |
PUBMED |
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| ERK |
|
Kidd M, Modlin IM, Eick GN, Camp RL, Mane SM
Role of CCN2/CTGF in the proliferation of Mastomys enterochromaffin-like
cells and gastric carcinoid development. Am J Physiol Gastrointest Liver
Physiol. 2007 Jan;292(1):G191-200. Epub 2006 Aug 31. |
PUBMED |
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Kidd M, Modlin IM, Gustafsson BI, Drozdov I, Hauso O,
Pfragner R. The luminal regulation of normal and neoplastic human EC
cell serotonin release is mediated by bile salts, amines, tastants and
olfactants. Am J Physiol Gastrointest Liver Physiol. 2008 Jun 12. [Epub
ahead of print] |
PUBMED |
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Lirk P, Haller I, Colvin HP, Lang L, Tomaselli B,
Klimaschewski L, Gerner P In vitro, inhibition of mitogen-activated
protein kinase pathways protects against bupivacaine- and ropivacaine-induced
neurotoxicity Anesth Analg. 2008 May;106(5):1456-64, table of
contents |
PUBMED |
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Perl M, Chung CS, Perl U, Lomas-Neira J, de
Paepe M, Cioffi WG, Ayala A Fas-induced pulmonary apoptosis and
inflammation during indirect acute lung injury. Am J Respir Crit Care
Med. 2007 Sep 15;176(6):591-601. Epub 2007 Jun 28 |
PUBMED |
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Singla DK, Singla RD, McDonald DE. Factors Released
from Embryonic Stem Cells inhibit Apoptosis in H9c2 cells through
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Yan Z, Zou H, Tian F, Grandis JR, Mixson AJ, Lu PY, Li
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Profita M, Bonanno A, Siena L, Bruno A, Ferraro M, Montalbano AM, Albano GD, Riccobono L, Casarosa P, Pieper MP, Gjomarkaj M. Smoke, Choline-Acetyl-Transferase, Muscarinic Receptors and fibroblast proliferation in COPD. J Pharmacol Exp Ther. 2009 Feb 3. [Epub ahead of print]
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Zou H, Thomas SM, Yan ZW, Grandis JR, Vogt A, Li LY Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells. FASEB J. 2009 Feb;23(2):425-32. Epub 2008 Oct 2.
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| Uddin MN, Horvat D, Childs EW, Puschett JB. Marinobufagenin causes endothelial cell monolayer hyperpermeability by altering Am J Physiol Regul Integr Comp Physiol. 2009 Jun;296(6):R1726-34. Epub 2009 Apr | PUBMED |
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| Kemp EH, Gavalas NG, Krohn KJ, Brown EM,
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Kanda N, Watanabe S. Prolactin enhances
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Holley SL, Fryer AA, Haycock JW, Grubb SE,
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Lirk P, Haller I, Colvin HP, Lang L, Tomaselli B,
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Uddin MN, Horvat D, Glaser SS, Mitchell BM, Puschett JB.
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Suga H, Eto H, Shigeura T, Inoue K, Aoi N, Kato H, Nishimura S, Manabe I, Gonda K, Yoshimura K. IFATS Series: FGF-2-induced HGF Secretion By Adipose-Derived Stromal Cells Inhibits Post-Injury Fibrogenesis Through A JNK-Dependent Mechanism. Stem Cells. 2008 Sep 4. [Epub ahead of print]
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Kanda N, Watanabe S. Prolactin enhances
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Naderi A, Teschendorff AE, Beigel J, Cariati
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| Soliman S, Aronson WJ, Barnard RJ. Analyzing Serum-Stimulated Prostate Cancer Cell Lines After Low-Fat, High-Fiber Evid Based Complement Alternat Med. 2009 Apr 17. | PUBMED |
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Kanda N, Watanabe S. Prolactin enhances
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Uddin MN, Horvat D, Glaser SS, Mitchell BM, Puschett JB.
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Cantiani L, Manara MC, Zucchini C, De Sanctis
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Gong P, Angelini DJ, Yang S, Xia G, Cross AS, Mann D,
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Uddin MN, Horvat D, Glaser SS, Mitchell BM, Puschett JB.
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Choudhari SR, Khan MA, Harris G, Picker D,
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Fan W, Yanase T, Nishi Y, Chiba S, Okabe T, Nomura M, Yoshimatsu H, Kato S, Takayanagi R, Nawata H. FUNCTIONAL POTENTIATION OF LEPTIN-STAT3 SIGNALING BY THE ANDROGEN RECEPTOR. Endocrinology. 2008 Aug 14. [Epub ahead of print]
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| Beales IL, Ogunwobi OO. Glycine-extended gastrin inhibits apoptosis in Barrett's oesophageal and J Mol Endocrinol. 2009 Apr;42(4):305-18. Epub 2009 Jan 19. | PUBMED |
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CASE Inhibitors
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Kroening PR, Barnes TW, Pease L, Limper A, Kita H,
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Addison WN, Azari F, S?ensen ES, Kaartinen MT, McKee
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Kroening PR, Barnes TW, Pease L, Limper A, Kita H,
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Hamidi SA, Prabhakar S, Said SI. Enhancement of pulmonary
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Melnick M, Mocarski ES, Abichaker G, Huang J, Jaskoll T.
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Piechocki MP, Yoo GH, Dibbley SK, Lonardo F. Breast
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Pinkerton MN, Wescott DC, Gaffey BJ, Beggs KT, Milne TJ,
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Raeder S, Utheim TP, Utheim OA, Nicolaissen B, Roald B,
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Tilton JC, Manion MM, Luskin MR, Johnson AJ, Patamawenu
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Wescott DC, Pinkerton MN, Gaffey BJ, Beggs KT, Milne TJ,
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Zhang Y, Woodruff M, Zhang Y, Miao J, Hanley G, Stuart C,
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Desai SP, Kojima K, Vacanti CA, Kodama S. Lidocaine inhibits NIH-3T3 cell multiplication by increasing the expression of cyclin-dependent kinase inhibitor 1A (p21). Anesth Analg. 2008 Nov;107(5):1592-7
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Sinha P, Okoro C, Foell D, Freeze HH, Ostrand-Rosenberg S, Srikrishna G. Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells. J Immunol. 2008 Oct 1;181(7):4666-75.
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Leatherbury, L, Yu, Q, Chatterjee, B, Walker, DL, Yu, Z., Tian, X., and Lo, CW A novel mouse model of X-linked cardiac hypertrophy. Am J Physiol Heart Circ Physiol 2008 April 18; 294: H2701-H2711
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Sinha S, Subramanian S, Proctor TM, Kaler LJ, Grafe M, Dahan R, Huan J, Vandenbark AA, Burrows GG, Offner H. A promising therapeutic approach for multiple sclerosis: recombinant T-cell receptor ligands modulate experimental autoimmune encephalomyelitis by reducing interleukin-17 production and inhibiting migration of encephalitogenic cells into the CNS.J Neurosci. 27(46):12531-9.
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Bernstein, M., Chakraborty, M., Wansley, E., Guo, Z., D., Franzusof, A., Mostbock, S., Sabzevari, H., Schlom, J., and Hodge, J.W. Recombinant Saccharomyces cerevisiae (yeast-CEA) as a potent activator of murine dendritic cells. Vaccine. 26:509-521.
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Yu J, Kindy MS, Gattoni-Celli S. Semi-Allogeneic Vaccine for T-Cell Lymphoma. J Translational Medicine, 5:39
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Secchiero, P., Corallini, F., di Iasio, MG., Gonelli, A., Barbarotto, E., and Zauli, G. TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release. Blood, 2005 May;105: 3413 - 3419.
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Luo, Y., Schwartz, C., Shin, S., Zeng, X., Chen, N., Wang, Y., Yu, X., and Rao, MS. A Focused Microarray to Assess Dopaminergic and Glial Cell Differentiation from Fetal Tissue or Embryonic Stem Cells. Stem Cells, 2006 Apr; 24: 865 - 875.
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Jaskoll, T., Abichaker, G., Sedghizadeh, PP., Bringas Jr, P., and Melnick, M. Cytomegalovirus induces abnormal chondrogenesis and osteogenesis during embryonic mandibular development. BMC Dev Biol, 2007 Nov; 8: 33.
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Propst JT, Fann SA, Franchini JL, Hansen KJ, Yost MJ, Lessner SM, Terracio L. Focused in vivo genetic analysis of implanted engineered myofascial constructs. J Invest Surg. 2008 Jan; 22(1):35-45.
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di Iasio MG, Secchiero P, Tiribelli M, Zauli G. Reduced expression of cell cycle-associated genes in B lymphocytes purified from the peripheral blood of early-stage B chronic lymphocytic leukaemia patients. Br J Haematol. 2009 Feb 3. [Epub ahead of print]
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Secchiero P, Melloni E, di Iasio MG, Tiribelli M, Rimondi E, Corallini F, Gattei V, Zauli G. Nutlin-3 upregulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feed-back anti-apoptotic mechanism. Blood. 2009 Feb 3. [Epub ahead of print]
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Secchiero P, Corallini F, Rimondi E, Chiaruttini C, di Iasio MG, Rustighi A, Del Sal G, Zauli G. Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells. Blood. 2008 Feb 1;111(3):1287-94. Epub 2007 Nov 13.
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Secchiero P, Zerbinati C, di Iasio MG, Melloni E, Tiribelli M, Grill V, Zauli G. Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells. Curr Drug Metab.2007 May;8(4):395-403.
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Secchiero P, di Iasio MG, Gonelli A, Barbarotto E, Melloni E, Tiribelli M, Chiaruttini C, Zauli G. Differential gene expression induction by TRAIL in B chronic lymphocytic leukemia (B-CLL) cells showing high versus low levels of Zap-70. J Cell Physiol. 2007 Oct;213(1):229-36.
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Secchiero P, Barbarotto E, Tiribelli M, Zerbinati C, di Iasio MG, Gonelli A, Cavazzini F, Campioni D, Fanin R, Cuneo A, Zauli G. Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL). Blood. 2006 May 15;107(10):4122-9.
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Secchiero P, Corallini F, Barbarotto E, Melloni E, di Iasio MG, Tiribelli M, Zauli G. Role of the RANKL/RANK system in the induction of interleukin-8 (IL-8) in B chronic lymphocytic leukemia (B-CLL) cells. J Cell Physiol. 2006 Apr;207(1):158-64.
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Secchiero P, Corallini F, di Iasio MG, Gonelli A, Barbarotto E, Zauli G. TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release. Blood. 2005 May 1;105(9):3413-9.
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Pucci S et al. Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression. Cell Cycle 2009, Feb 1;8(3):473-81.
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| Qadura M, Waters B, Burnett E, Chegeni R, Bradshaw S, Hough C, Othman M, Lillicrap D. Recombinant and plasma-derived factor VIII products induce distinct splenic Blood. 2009 Jul 23;114(4):871-80. Epub 2009 May 1. | PUBMED |
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| Bearzi C, Leri A, Lo Monaco F, Rota M, Gonzalez A, Hosoda T, Pepe M, Qanud K, Ojaimi C, Bardelli S, D'Amario D, D'Alessandro DA, Michler RE, Dimmeler S, Zeiher AM, Urbanek K, Hintze TH, Kajstura J, Anversa P. Identification of a coronary vascular progenitor cell in the human heart. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15885-90. Epub 2009 Aug 27. | PUBMED |
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EpiTect ChIP qPCR
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Subbaramaiah K, Hudis C, Chang SH, Hla T, Dannenberg AJ.
EP2 and EP4 Receptors Regulate Aromatase Expression in Human Adipocytes
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Sampath D, Calin GA, Puduvalli VK, Gopisetty G, Taccioli C, Liu CG, Ewald B, Liu C, Keating MJ, Plunkett W. Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase, Itch for degradation. Blood. 2008 Dec 18. [Epub ahead of print]
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Genua M, Pandini G, Sisci D, Castoria G, Maggiolini M, Vigneri R, Belfiore
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Nagai Y, Yonemitsu S, Erion DM, Iwasaki T, Stark R, Weismann D, Dong J,
Zhang D, Jurczak MJ, L?ffler MG, Cresswell J, Yu XX, Murray SF, Bhanot S,
Monia BP, Bogan JS, Samuel V, Shulman GI. The role of peroxisome
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Gemenetzidis E, Bose A, Riaz AM, Chaplin T, Young BD, Ali M, Sugden D,
Thurlow JK, Cheong SC, Teo SH, Wan H, Waseem A, Parkinson EK, Fortune F, Teh
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Tanimoto T, Hattori N, Senoo T, Furonaka M, Ishikawa N, Fujitaka K, Haruta
Y, Yokoyama A, Igarashi K, Kohno N. Genetic ablation of the Bach1 gene
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Montoya-Durango DE, Liu Y, Teneng I, Kalbfleisch T, Lacy ME, Steffen MC,
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Calonje M, Sanchez R, Chen L, Sung ZR. EMBRYONIC FLOWER1 participates in
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Lyakhov IG, Krishnamachari A, Schneider TD. Discovery of novel tumor
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Panchanathan R, Shen H, Bupp MG, Gould KA, Choubey D. Female and male sex
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Klunker S, Chong MM, Mantel PY, Palomares O, Bassin C, Ziegler M, Rückert
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ELISArray Kits
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Guo X, Hiroko, Kitmura T, Taketo M, Oshima M. Stromal
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| Zhang L, Stanford M, Liu J, Barrett C, Jiang L, Barclay AN, McFadden G. Inhibition of macrophage activation by the myxoma virus M141 protein (vCD200). J Virol. 2009 Sep;83(18):9602-7. Epub 2009 Jul 1. | PUBMED |
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| Reynolds AD, Stone DK, Mosley RL, Gendelman HE. Nitrated {alpha}-synuclein-induced alterations in microglial immunity are J Immunol. 2009 Apr 1;182(7):4137-49. | PUBMED |
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Cignal™ Reporter Assay System
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Greer, R. M. et al.. SMAC Mimetic (JP1201) Sensitizes Non-Small Cell Lung Cancers to Multiple Chemotherapy Agents in an IAP-Dependent but TNF-α-Independent Manner. Cancer Res., 2011. |
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Campeau, P.M., Rafei, M., Boivin, M.-N., Sun, Y., Grabowski, G.A., and Galipeau, J. Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome. Blood, 2009 |
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Elyakim, E. et al.. hsa-miR-191 Is a Candidate Oncogene Target for Hepatocellular Carcinoma Therapy. Cancer Res., 2010. |
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Zughaier, S.M.. Neisseria meningitidis capsular polysaccharides induce inflammatory responses via TLR2 and TLR4-MD-2. JLB, 2011. |
PUBMED |
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Panas, M.W., Xie, Z., Panas, H.N., Hoener, M.C., Vallender, E.J., and Miller, G.M. Trace Amine Associated Receptor 1 Signaling in Activated Lymphocytes. J. Neuroimmune Pharmacol., 2011. |
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Lichten LA, Ryu MS, Guo L, Embury J, Cousins RJ. MTF-1-mediated repression of the zinc transporter Zip10 is alleviated by zinc restriction. PLoS One, 2011. |
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Seah C, Levy MA, Jiang Y, Mokhtarzada S, Higgs DR,
Gibbons RJ, Berube NG. Neuronal death resulting from targeted disruption
of the Snf2 protein ATRX is mediated by p53. J. Neurosci., Nov 2008; 28: 12570 - 12580. |
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Sun X, Ritzenthaler JD, Zheng Y, Roman J, Han S.
Rosiglitazone inhibits alpha4 nicotinic acetylcholine receptor
expression in human lung carcinoma cells through peroxisome proliferator-activated
receptor gamma-independent signals. Mol Cancer Ther. 2009
Jan;8(1):110-8. |
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Healy NC, O'Connor R Sequestration of PDLIM2 in the cytoplasm of monocytic/macrophage cells is associated with adhesion and increased nuclear activity of NF-{kappa}B. J Leukoc Biol. 2008 Dec 3. [Epub ahead of print]
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McKay BR, O'Reilly CE, Phillips SM, Tarnopolsky MA, Parise G. Co-expression of IGF-1 family members with myogenic regulatory factors following acute damaging muscle-lengthening contractions in humans. J Physiol. 2008 Nov 15;586(Pt 22):5549-60. Epub 2008 Sep 25.
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| Hsu LJ, Schultz L, Hong Q, Van Moer K, Heath J, Li MY, Lai FJ, Lin SR, Lee MH, Lo CP, Lin YS, Chen ST, Chang NS. Transforming growth factor beta1 signaling via interaction with cell surface J Biol Chem. 2009 Jun 5;284(23):16049-59. Epub 2009 Apr 14. | PUBMED |
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| Kirchhoff T, Chen ZQ, Gold B, Pal P, Gaudet
MM, Kosarin K, Levine DA, Gregersen P, Spencer S, Harlan M, Robson M, Klein
RJ, Hudis CA, Norton L, Dean M, Offit K. The 6q22.33 locus and breast cancer
susceptibility. Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2468-75.
Epub 2009 Aug 18. | PUBMED |
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| Kawakami K, Hirata H, Yamamura S, Kikuno N,
Saini S, Majid S, Tanaka Y, Kawamoto K, Enokida H, Nakagawa M, Dahiya R.
Functional significance of Wnt inhibitory factor-1 gene in kidney cancer.
Cancer Res. 2009 Nov 15;69(22):8603-10. Epub 2009 Nov 3. | PUBMED |
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| Catalgol B, Ziaja I, Breusing N, Jung T,
Höhn A, Alpertunga B, Schroeder P, Chondrogianni N, Gonos ES, Petropoulos
I, Friguet B, Klotz LO, Krutmann J, Grune T. The proteasome is an integral
part of solar ultraviolet a radiation-induced gene expression. J Biol Chem.
2009 Oct 30;284(44):30076-86. Epub 2009 Aug 18. | PUBMED |
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| Pavlov TS, Levchenko V, Karpushev AV,
Vandewalle A, Staruschenko A. Peroxisome proliferator-activated receptor
gamma antagonists decrease Na+ transport via the epithelial Na+ channel. Mol
Pharmacol. 2009 Dec;76(6):1333-40. Epub 2009 Sep 14. | PUBMED |
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| Sharma SD, Meeran SM, Katiyar N, Tisdale
GB, Yusuf N, Xu H, Elmets CA, Katiyar SK. IL-12 deficiency suppresses
12-O-tetradecanoylphorbol-13-acetate-induced skin tumor development in
7,12-dimethylbenz(a)anthracene-initiated mouse skin through inhibition of
inflammation. Carcinogenesis. 2009 Nov;30(11):1970-7. Epub 2009 Sep 16. | PUBMED |
| | |
| Sharma S, Lichtenstein A. Aberrant splicing
of the E-cadherin transcript is a novel mechanism of gene silencing in
chronic lymphocytic leukemia cells. Blood. 2009 Nov 5;114(19):4179-85. Epub
2009 Sep 10. | PUBMED |
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| Kalogeropoulos M, Varanasi SS, Olstad OK,
Sanderson P, Gautvik VT, Reppe S, Francis RM, Gautvik KM, Birch MA, Datta
HK. Zic1 transcription factor in bone: neural developmental protein
regulates mechanotransduction in osteocytes. FASEB J. 2010 Apr 6. [Epub
ahead of print] | PUBMED |
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| Barnholt KE, Kota RS, Aung HH, Rutledge JC.
Adenosine blocks IFN-gamma-induced phosphorylation of STAT1 on serine 727 to
reduce macrophage activation. J Immunol. 2009 Nov 15;183(10):6767-77. Epub
2009 Oct 21. | PUBMED |
| | |
| Liu P, Li H, Cepeda J, Xia Y, Kempf JA, Ye
H, Zhang LQ, Ye SQ. Regulation of inflammatory cytokine expression in
pulmonary epithelial cells by pre-B-cell colony-enhancing factor via a
nonenzymatic and AP-1-dependent mechanism. J Biol Chem. 2009 Oct
2;284(40):27344-51. Epub 2009 Aug 4. | PUBMED |
| | |
| Cignal™ Lenti Reporter Assay System |
| Kim YK, Ha HH, Lee JS, Bi X, Ahn YH, Hajar
S, Lee JJ, Chang YT. Control of muscle differentiation by a
mitochondria-targeted fluorophore. J Am Chem Soc. 2010 Jan 20;132(2):576-9. | PUBMED |
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Cignal™ Finder Reporter Arrays
|
Greer, R. M. et al.. SMAC Mimetic (JP1201) Sensitizes Non-Small Cell Lung Cancers to Multiple Chemotherapy Agents in an IAP-Dependent but TNF-α-Independent Manner. Cancer Res., 2011. |
PUBMED |
|
|
|
|
Campeau, P.M., Rafei, M., Boivin, M.-N., Sun, Y., Grabowski, G.A., and Galipeau, J. Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome. Blood, 2009 |
PUBMED |
|
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Elyakim, E. et al.. hsa-miR-191 Is a Candidate Oncogene Target for Hepatocellular Carcinoma Therapy. Cancer Res., 2010. |
PUBMED |
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|
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Zughaier, S.M.. Neisseria meningitidis capsular polysaccharides induce inflammatory responses via TLR2 and TLR4-MD-2. JLB, 2011. |
PUBMED |
|
|
|
|
Panas, M.W., Xie, Z., Panas, H.N., Hoener, M.C., Vallender, E.J., and Miller, G.M. Trace Amine Associated Receptor 1 Signaling in Activated Lymphocytes. J. Neuroimmune Pharmacol., 2011. |
PUBMED |
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|
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Lichten LA, Ryu MS, Guo L, Embury J, Cousins RJ. MTF-1-mediated repression of the zinc transporter Zip10 is alleviated by zinc restriction. PLoS One, 2011. |
PUBMED |
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Naouar, M. et al. The new protein FAM110B regulates the expression of E-cadherin and is involved in cell migration and invasion. Cancer Res., 2011. |
PUBMED |
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RT² First Strand Kit
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Bruno RD, Gover TD, Burger AM, Brodie AM, Njar VC. 17alpha-Hydroxylase/17,20 lyase inhibitor VN/124-1 inhibits growth of androgen-independent prostate cancer cells via induction of the endoplasmic reticulum stress response. Mol Cancer Ther. 2008 Sep;7(9):2828-36.
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Kerber M, Reiss Y, Wickersheim A, Jugold M, Kiessling F, Heil M, Tchaikovski V, Waltenberger J, Shibuya M, Plate KH, Machein MR. Flt-1 signaling in macrophages promotes glioma growth in vivo. Cancer Res. 2008 Sep 15;68(18):7342-51.
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| Hideshima T, Ikeda H, Chauhan D, Okawa Y, Raje N, Podar K, Mitsiades C, Munshi NC, Richardson PG, Carrasco RD, Anderson KC. Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma Blood. 2009 Jul 30;114(5):1046-52. Epub 2009 May 12. | PUBMED |
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| Hideshima T, Chauhan D, Kiziltepe T, Ikeda H, Okawa Y, Podar K, Raje N, Protopopov A, Munshi NC, Richardson PG, Carrasco RD, Anderson KC. Biologic sequelae of I{kappa}B kinase (IKK) inhibition in multiple myeloma: Blood. 2009 May 21;113(21):5228-36. Epub 2009 Mar 6. | PUBMED |
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| Xiang J, McLinden JH, Rydze RA, Chang Q,
Kaufman TM, Klinzman D, Stapleton JT. Viruses within the Flaviviridae
decrease CD4 expression and inhibit HIV replication in human CD4+ cells. J
Immunol. 2009 Dec 15;183(12):7860-9 | PUBMED |
| | |
| Chan SK, Riley PR, Price KL, McElduff F,
Winyard PJ, Welham SJ, Woolf AS, Long DA. Corticosteroid-induced kidney
dysmorphogenesis is associated with deregulated expression of known
cystogenic molecules, as well as Indian hedgehog. Am J Physiol Renal Physiol.
2010 Feb;298(2):F346-56. Epub 2009 Dec 9. | PUBMED |
XpressRef Human Universal Total RNA
|
Palermo A, Doyonnas R, Bhutani N, Pomerantz J, Alkan O, Blau HM. Nuclear reprogramming in heterokaryons is rapid, extensive, and bidirectional. FASEB J. 2009 Jan 13. [Epub ahead of print]
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| Devosse T, Guillabert A, D'Haene N, Berton A, De Nadai P, Noel S, Brait M, Franssen JD, Sozzani S, Salmon I, Parmentier M. Formyl peptide receptor-like 2 is expressed and functional in plasmacytoid J Immunol. 2009 Apr 15;182(8):4974-84. | PUBMED |
RT² qPCR-Grade RNA isolation kit
| Dyer KD, Percopo CM, Fischer ER, Gabryszewski SJ, Rosenberg HF. Pneumoviruses infect eosinophils and elicit MyD88-dependent release of Blood. 2009 Sep 24;114(13):2649-56. Epub 2009 Aug 3. | PUBMED |
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| Qiu Z, Dyer KD, Xie Z, Radinger M, Rosenberg HF. GATA transcription factors regulate the expression of the human J Biol Chem. 2009 May 8;284(19):13099-109. Epub 2009 Mar 10. | PUBMED |
SureFECT™ Transfection Reagent
| Rashid S, Pilecka I, Torun A, Olchowik M, Bielinska B, Miaczynska M. Endosomal adaptor proteins APPL1 and APPL2 are novel activators of J Biol Chem. 2009 Jul 3;284(27):18115-28. Epub 2009 May 11. | PUBMED |
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EpiTect Methyl qPCR Arrays &
Assays
| Jaspers I, Horvath KM, Zhang W, Brighton
LE, Carson JL, Noah TL.Reduced Expression of IRF7 in Nasal Epithelial
Cells from Smokers after Infection with Influenza. Am J Respir Cell Mol
Biol. 2010 Sep;43(3):368-75. Epub 2009 Oct 30. | PUBMED |
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Chamberlain SJ, Chen PF, Ng KY, Bourgois-Rocha F,
Lemtiri-Chlieh F, Levine ES, Lalande M. Induced pluripotent stem cell
models of the genomic imprinting disorders Angelman and Prader-Willi
syndromes. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17668-73. Epub
2010 Sep 27. |
PUBMED |
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Jung H. Kim, Saravana M. Dhanasekaran, John R. Prensner,
Xuhong Cao, Daniel Robinson, Shanker Kalyana-Sundaram, Christina Huang,
Sunita Shankar, Xiaojun Jing, Matthew Iyer, Ming Hu, Lee Sam, Catherine
Grasso, Christopher A. Maher, Nallasivam Palanisamy, Rohit Mehra, Hal D.
Kominsky, Javed Siddiqui, Jindan Yu, Zhaohui S. Qin, and Arul M.
Chinnaiyan Deep sequencing reveals distinct patterns of DNA methylation
in prostate cancer Genome Res., Jul 2011; 21: 1028 - 1041. |
PUBMED |
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Kibriya MG, Raza M, Jasmine F, Roy S, Paul-Brutus R,
Rahaman R, Dodsworth C, Rakibuz-Zaman M, Kamal M, Ahsan H. A genome-wide
DNA methylation study in colorectal carcinoma BMC Medical Genomics, Jun
2011; 4(10:50 |
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Ceccarelli V, Racanicchi S, Martelli MP, Nocentini G,
Fettucciari K, Riccardi C, Marconi P, Di Nardo P, Grignani F, Binaglia
L, Vecchini A. Eicosapentaenoic Acid Demethylates a Single CpG That
Mediates Expression of Tumor Suppressor CCAAT/Enhancer-binding Protein
{delta} in U937 Leukemia Cells. J Biol Chem. 2011 Aug
5;286(31):27092-102 |
PUBMED |
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Complete Array List